
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : Otenaproxesul
Therapeutic Area : Musculoskeletal
Study Phase : Phase II
Sponsor : Taro Pharmaceutical Industries
Deal Size : Undisclosed
Deal Type : Acquisition
Sun Pharma Subsidiary Taro Acquires Antibe Therapeutics
Details : Through the acquisition, Taro will leverage Antibe pipeline, including ATB-346 (otenaproxesul), a novel NSAID. It is being evaluated for the treatment of Osteoarthritis.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
January 16, 2025
Lead Product(s) : Otenaproxesul
Therapeutic Area : Musculoskeletal
Highest Development Status : Phase II
Sponsor : Taro Pharmaceutical Industries
Deal Size : Undisclosed
Deal Type : Acquisition

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Lead Product(s) : Otenaproxesul
Therapeutic Area : Neurology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Antibe Announces FDA Clinical Hold on Otenaproxesul and Legal Action by Nuance
Details : ATB-346 (otenaproxesul) is a novel hydrogen sulfide-releasing, nonsteroidal anti-inflammatory drug, which is being evaluated for the treatment of acute pain.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
April 01, 2024
Lead Product(s) : Otenaproxesul
Therapeutic Area : Neurology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Otenaproxesul
Therapeutic Area : Neurology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Antibe Reports PK Results of First Clinical Study of Otenaproxesul’s New Formulation
Details : ATB-346 (otenaproxesul) is a novel NSAID that releases hydrogen sulfide. Antibe is leveraging the drug's remarkable potency, gastrointestinal ("GI") protection and overall safety profile for use in acute pain indications.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
November 09, 2023
Lead Product(s) : Otenaproxesul
Therapeutic Area : Neurology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Otenaproxesul
Therapeutic Area : Neurology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Antibe Completes First Clinical Study of Otenaproxesul’s New Formulation
Details : ATB-346 (otenaproxesul) ia a COX-2 inhibitor which is in clinical development as a safer alternative to opioids and today’s NSAIDs that releases hydrogen sulfide, for acute pain.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
November 01, 2023
Lead Product(s) : Otenaproxesul
Therapeutic Area : Neurology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Otenaproxesul
Therapeutic Area : Neurology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Antibe Initiates First Clinical Study of Otenaproxesul’s New Formulation
Details : ATB-346 (otenaproxesul) is a novel NSAID that releases hydrogen sulfide. Antibe is leveraging the drug's remarkable potency, gastrointestinal ("GI") protection and overall safety profile for use in acute pain indications.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
October 18, 2023
Lead Product(s) : Otenaproxesul
Therapeutic Area : Neurology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Otenaproxesul
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Antibe Receives Approval to Initiate PK/PD Study of Otenaproxesul
Details : ATB-346 (otenaproxesul) is a novel NSAID that releases hydrogen sulfide. Antibe is leveraging the drug's remarkable potency, gastrointestinal ("GI") protection and overall safety profile for use in acute pain indications.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
September 28, 2023
Lead Product(s) : Otenaproxesul
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Otenaproxesul
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Antibe Provides Development Update for Otenaproxesul
Details : The new formulation’s benefits include rapid dissolution mechanics, accelerating otenaproxesul’s (ATB-346) onset of action, a key benchmark for acute pain medications; and enhanced bioavailability, enabling a significant dose reduction compared to it...
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
October 12, 2022
Lead Product(s) : Otenaproxesul
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Otenaproxesul
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Antibe Academic Collaborator to Present Clinical Data at PAINWeek 2022
Details : ATB-346 (otenaproxesul) is novel nonsteroidal anti-inflammatory drug (“NSAID”) that releases hydrogen sulfide. Antibe is leveraging the drug’s remarkable potency, gastrointestinal (“GI”) protection and overall safety profile for use in acute pa...
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
September 06, 2022
Lead Product(s) : Otenaproxesul
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Otenaproxesul
Therapeutic Area : Musculoskeletal
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Antibe Therapeutics Provides Clinical Update for Otenaproxesul
Details : The AME study had enrolled a total of 42 subjects on either a 75 mg or 100 mg daily dose of otenaproxesul, of whom 35 had completed the 28-day drug administration period, with seven subjects having been administered the drug for 21 days.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
August 03, 2021
Lead Product(s) : Otenaproxesul
Therapeutic Area : Musculoskeletal
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Otenaproxesul
Therapeutic Area : Musculoskeletal
Study Phase : Phase II
Sponsor : Veristat
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Antibe’s lead drug, otenaproxesul, is entering Phase III for the treatment of osteoarthritis pain. Additional assets under development include a safer alternative to opioids for peri-operative pain, and a GI-protective alternative to low-dose aspirin.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
March 29, 2021
Lead Product(s) : Otenaproxesul
Therapeutic Area : Musculoskeletal
Highest Development Status : Phase II
Sponsor : Veristat
Deal Size : Inapplicable
Deal Type : Inapplicable
