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    [{"orgOrder":0,"company":"Anthos Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Cardiology\/Vascular Diseases","country":"U.S.A","productType":"Antibody","year":"2024","type":"Inapplicable","leadProduct":"Abelacimab","moa":"Factor XI\/XIa","graph1":"Cardiology\/Vascular Diseases","graph2":"Phase III","graph3":"Anthos Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Intravenous Injection","sponsorNew":"Anthos Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Anthos Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Anthos Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Cardiology\/Vascular Diseases","country":"U.S.A","productType":"Antibody","year":"2023","type":"Inapplicable","leadProduct":"Abelacimab","moa":"Factor XI\/XIa","graph1":"Cardiology\/Vascular 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Injection","sponsorNew":"Anthos Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Anthos Therapeutics \/ Inapplicable"}]

    Find Clinical Drug Pipeline Developments & Deals by Anthos Therapeutics

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                            01

                            Anthos Therapeutics

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                            Anthos Therapeutics

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                            Lead Product(s) : Abelacimab

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : Novartis Pharmaceuticals Corporation

                            Deal Size : $3,075.0 million

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Novartis to Acquire Anthos Therapeutics for USD 925 Million Upfront

                            Details : Through the acquisition, Novartis will strengthen its cardiovascular portfolio with Anthos' MAA868 (abelacimab), a potential monoclonal antibody for the treatment of atrial fibrillation.

                            Product Name : MAA868

                            Product Type : Antibody

                            Upfront Cash : $925.0 million

                            February 11, 2025

                            Lead Product(s) : Abelacimab

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : Novartis Pharmaceuticals Corporation

                            Deal Size : $3,075.0 million

                            Deal Type : Acquisition

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                            02

                            Anthos Therapeutics

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                            American Thoracic Society
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                            Anthos Therapeutics

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                            American Thoracic Society
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                            Lead Product(s) : Abelacimab

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Anthos Highlights Abelacimab’s Bleeding Reduction Over Rivaroxaban in AZALEA-TIMI 71

                            Details : MAA868 (abelacimab) is a highly selective, mAb designed to induce hemostasis-sparing anticoagulation through Factor XI inhibition, in patients with Atrial Fibrillation with high risk of stroke.

                            Product Name : MAA868

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            November 16, 2024

                            Lead Product(s) : Abelacimab

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Anthos Therapeutics

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                            American Thoracic Society
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                            Anthos Therapeutics

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                            American Thoracic Society
                            Not Confirmed
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                            Lead Product(s) : Abelacimab

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Anthos Announces 84% Transition to Abelacimab in AZALEA-TIMI 71 Study for AFib at a Stroke

                            Details : MAA868 (abelacimab) is a highly selective, monoclonal antibody designed to induce effective hemostasis-sparing anticoagulation through Factor XI inhibition, in patients with Atrial Fibrillation.

                            Product Name : MAA868

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            June 06, 2024

                            Lead Product(s) : Abelacimab

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Anthos Therapeutics

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                            American Thoracic Society
                            Not Confirmed

                            Anthos Therapeutics

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                            American Thoracic Society
                            Not Confirmed
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                            Lead Product(s) : Abelacimab

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Anthos Therapeutics Shares New Data on Abelacimab's Low Bleeding Risk

                            Details : MAA868 (abelacimab) is a highly selective, fully human monoclonal antibody designed to induce effective hemostasis-sparing anticoagulation through Factor XI inhibition.

                            Product Name : MAA868

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            February 09, 2024

                            Lead Product(s) : Abelacimab

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Anthos Therapeutics

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                            American Thoracic Society
                            Not Confirmed

                            Anthos Therapeutics

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                            American Thoracic Society
                            Not Confirmed
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                            Lead Product(s) : Abelacimab

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Anthos Therapeutics' Novel Dual-Acting Factor XI/XIa Inhibitor, Abelacimab 150 mg, Demonstrated a 67% Reductio...

                            Details : MAA868 (abelacimab) is a highly selective, fully human monoclonal antibody designed to induce effective hemostasis-sparing anticoagulation through Factor XI inhibition.

                            Product Name : MAA868

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            November 13, 2023

                            Lead Product(s) : Abelacimab

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Anthos Therapeutics

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                            American Thoracic Society
                            Not Confirmed

                            Anthos Therapeutics

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                            American Thoracic Society
                            Not Confirmed
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                            Lead Product(s) : Abelacimab

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Memphis Seniors with a History of Atrial Fibrillation Joining New Research Study

                            Details : MAA868 (abelacimab) is a highly selective, fully human monoclonal antibody designed to induce effective hemostasis-sparing anticoagulation through Factor XI inhibition.

                            Product Name : MAA868

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            September 20, 2023

                            Lead Product(s) : Abelacimab

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Anthos Therapeutics

                            U.S.A arrow
                            American Thoracic Society
                            Not Confirmed

                            Anthos Therapeutics

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                            American Thoracic Society
                            Not Confirmed
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                            Lead Product(s) : Abelacimab

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Atrial Fibrillation Study with Abelacimab Stopped Early by the Data Monitoring Committee Due to an Overwhelmin...

                            Details : MAA868 (abelacimab) is a highly selective, fully human monoclonal antibody designed to induce effective hemostasis-sparing anticoagulation through Factor XI inhibition, which is investigated for patients with atrial fibrillation at moderate-to-high risk ...

                            Product Name : MAA868

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            September 18, 2023

                            Lead Product(s) : Abelacimab

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Anthos Therapeutics

                            U.S.A arrow
                            American Thoracic Society
                            Not Confirmed

                            Anthos Therapeutics

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                            American Thoracic Society
                            Not Confirmed
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                            Lead Product(s) : Abelacimab

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : Itreas

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Regulatory Authorities in China and Japan Approve Clinical Trials for Anthos Therapeutics' Dual-Acting Factor ...

                            Details : MAA868 (abelacimab) is a highly selective, fully human monoclonal antibody designed to induce effective hemostasis-sparing anticoagulation through Factor XI inhibition.

                            Product Name : MAA868

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            August 06, 2023

                            Lead Product(s) : Abelacimab

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : Itreas

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Anthos Therapeutics

                            U.S.A arrow
                            American Thoracic Society
                            Not Confirmed

                            Anthos Therapeutics

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                            American Thoracic Society
                            Not Confirmed
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                            Lead Product(s) : Abelacimab

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            First Patient Enrolled in Phase 3 Trial Evaluating Abelacimab in High-Risk Patients with Atrial Fibrillation D...

                            Details : MAA868 (Abelacimab) is a highly selective, fully human monoclonal antibody designed to induce effective hemostasis-sparing anticoagulation through Factor XI inhibition. It has received FDA Fast-Track Designations for the prevention systemic embolism with...

                            Product Name : MAA868

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            March 01, 2023

                            Lead Product(s) : Abelacimab

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Anthos Therapeutics

                            U.S.A arrow
                            American Thoracic Society
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                            Anthos Therapeutics

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                            American Thoracic Society
                            Not Confirmed
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                            Lead Product(s) : Abelacimab

                            Therapeutic Area : Hematology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Anthos Therapeutics Launches Second Phase 3 Clinical Trial of Its Dual-acting Factor XI Inhibitor, Abelacimab

                            Details : MAA868 (abelacimab) is dual-acting fully human monoclonal antibody targeting both Factor XI and Factor XIa with high affinity and selectivity, targets active domain of Factor XI, demonstrating dual inhibitory activity against both Factor XI and its activ...

                            Product Name : MAA868

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            August 25, 2022

                            Lead Product(s) : Abelacimab

                            Therapeutic Area : Hematology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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