
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : AN2-502998
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Drugs for Neglected Diseases initiative
Deal Size : Undisclosed
Deal Type : Collaboration
AN2 and DNDi Collaborate on Clinical Development of Promising New Oral Compound
Details : The collaboration aims to advance clinical development of AN2-502998, AN2’s oral drug candidate in development for the treatment of chronic Chagas disease.
Product Name : AN2-502998
Product Type : Miscellaneous
Upfront Cash : Undisclosed
July 23, 2025
Lead Product(s) : AN2-502998
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Drugs for Neglected Diseases initiative
Deal Size : Undisclosed
Deal Type : Collaboration

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Lead Product(s) : AN2-502998
Therapeutic Area : Undisclosed
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
First-in-Human Trial of Oral AN2-502998
Details : AN2-502998 is a Other Small Molecule drug candidate, which is currently being evaluated in Phase I clinical studies for the treatment of unspecified medical condition.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
June 17, 2025
Lead Product(s) : AN2-502998
Therapeutic Area : Undisclosed
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Epetraborole
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II/ Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
AN2 Provides Strategic Update for EBO-301 Trial in Treatment Refractory MAC Lung Disease
Details : EBO-301 (epetraborole) is a boron-containing oral inhibitor of bacterial leucyl-tRNA synthetase. It is being developed for treatment-refractory mycobacterium avium complex lung disease.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
February 24, 2025
Lead Product(s) : Epetraborole
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II/ Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Undisclosed
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Discovery Platform
Sponsor : Bill & Melinda Gates Foundation
Deal Size : Undisclosed
Deal Type : Funding
AN2 Therapeutics Receives Grant for Boron-Based TB and Malaria Therapies
Details : The funding will aims to support the company to discover novel, boron containing small molecules for the treatment of tuberculosis (TB) and malaria.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
October 17, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Discovery Platform
Sponsor : Bill & Melinda Gates Foundation
Deal Size : Undisclosed
Deal Type : Funding

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Lead Product(s) : Epetraborole
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II/ Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
AN2 Therapeutics Updates EBO-301 Study for Epetraborole in MAC Lung Disease
Details : EBO-301 (epetraborole) is a boron-containing oral inhibitor of bacterial leucyl-tRNA synthetase. It is being developed for treatment-refractory mycobacterium avium complex lung disease.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
August 08, 2024
Lead Product(s) : Epetraborole
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II/ Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Epetraborole
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II/ Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
AN2 Pauses Enrollment in Phase 3 of Epetraborole for Refractory MAC Lung Disease
Details : EBO-301 (epetraborole) is a boron-containing oral inhibitor of bacterial leucyl-tRNA synthetase. It is being developed for treatment-refractory mycobacterium avium complex lung disease.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
February 12, 2024
Lead Product(s) : Epetraborole
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II/ Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : AN15368
Therapeutic Area : Infections and Infectious Diseases
Study Phase : IND Enabling
Recipient : University of Georgia
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : The agreement aims to advance the development of AN2-502998 (formerly known as AN15368), a boron-based small molecule therapeutic under development for the treatment of Chagas disease.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
October 18, 2023
Lead Product(s) : AN15368
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : IND Enabling
Recipient : University of Georgia
Deal Size : Undisclosed
Deal Type : Licensing Agreement

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Lead Product(s) : Undisclosed
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Discovery
Sponsor : Bill & Melinda Gates Foundation
Deal Size : Undisclosed
Deal Type : Funding
Details : The funding will support the discovery of novel inhibitors of aminoacyl-tRNA synthetases using AN2’s proprietary boron chemistry platform for the treatment of tuberculosis and malaria.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
September 26, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Discovery
Sponsor : Bill & Melinda Gates Foundation
Deal Size : Undisclosed
Deal Type : Funding

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Lead Product(s) : Epetraborole
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II/ Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : AN2-501971 (epetraborole) is a boron-containing, orally-available, small molecule inhibitor of bacterial leucyl-tRNA synthetase, or LeuRS, an enzyme, which is investigated for the treatment of refractory mycobacterium avium complex lung disease.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
September 13, 2023
Lead Product(s) : Epetraborole
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II/ Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Epetraborole
Therapeutic Area : Undisclosed
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
A Study to Assess the Effects of Epetraborole on the QT Interval in Healthy Adult Subjects
Details : Epetraborole is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of undefined medical condition.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
August 16, 2023
Lead Product(s) : Epetraborole
Therapeutic Area : Undisclosed
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
