[{"orgOrder":0,"company":"Amplo Biotechnology","sponsor":"NIH-NIAMS","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Undisclosed","year":"2023","type":"Funding","leadProduct":"AMP-201","moa":"Undisclosed","graph1":"Genetic Disease","graph2":"Preclinical","graph3":"Amplo Biotechnology","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Amplo Biotechnology \/ NIH-NIAMS","highestDevelopmentStatusID":"4","companyTruncated":"Amplo Biotechnology \/ NIH-NIAMS"},{"orgOrder":0,"company":"Amplo Biotechnology","sponsor":"Andelyn Biosciences","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Protein","year":"2025","type":"Partnership","leadProduct":"AMP-101","moa":"DOK7","graph1":"Genetic Disease","graph2":"Preclinical","graph3":"Amplo Biotechnology","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Amplo Biotechnology \/ Andelyn Biosciences","highestDevelopmentStatusID":"4","companyTruncated":"Amplo Biotechnology \/ Andelyn Biosciences"}]

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                          Top Deals by Deal Size (USD bn)

                          01

                          ESCRS
                          Not Confirmed
                          ESCRS
                          Not Confirmed

                          Details : The partnership centers on manufacturing clinical-grade AAV vectors using Andelyn's suspension AAV Curator® platform to support Amplo’s NMJ-focused gene therapy candidates, including AMP-101.

                          Product Name : AMP-101

                          Product Type : Protein

                          Upfront Cash : Undisclosed

                          August 21, 2025

                          Lead Product(s) : AMP-101

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Preclinical

                          Sponsor : Andelyn Biosciences

                          Deal Size : Undisclosed

                          Deal Type : Partnership

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                          02

                          ESCRS
                          Not Confirmed
                          ESCRS
                          Not Confirmed

                          Details : The grant will provide substantial funding for the advancement of AMP-201, an AAV-ColQ gene therapy designed to address the severe congenital myasthenic syndrome (CMS) caused by Collagen Q (ColQ) Deficiency.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          May 30, 2023

                          Lead Product(s) : AMP-201

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Preclinical

                          Sponsor : NIH-NIAMS

                          Deal Size : Undisclosed

                          Deal Type : Funding

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