[{"orgOrder":0,"company":"Amarex Clinical Research","sponsor":"SyneuRx","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"U.S.A","productType":"Miscellaneous","year":"2017","type":"Inapplicable","leadProduct":"Sodium Benzoate","moa":"Amino acid metabolism","graph1":"Psychiatry\/Psychology","graph2":"Phase II\/ Phase III","graph3":"Amarex Clinical Research","amount2":0,"highestDevelopmentShortName":"Ph II\/III","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Amarex Clinical Research \/ Amarex Clinical Research","highestDevelopmentStatusID":"9","companyTruncated":"Amarex Clinical Research \/ Amarex Clinical Research"},{"orgOrder":0,"company":"Amarex Clinical Research","sponsor":"CytoDyn","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody, Unconjugated","year":"2020","type":"Inapplicable","leadProduct":"Leronlimab","moa":"C-C chemokine receptor type 5","graph1":"Oncology","graph2":"Phase II","graph3":"Amarex Clinical Research","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Amarex Clinical Research \/ Amarex Clinical Research","highestDevelopmentStatusID":"8","companyTruncated":"Amarex Clinical Research \/ Amarex Clinical Research"},{"orgOrder":0,"company":"Amarex Clinical Research","sponsor":"CytoDyn","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Antibody, Unconjugated","year":"2020","type":"Inapplicable","leadProduct":"Leronlimab","moa":"C-C chemokine receptor type 5","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"Amarex Clinical Research","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Injection","sponsorNew":"Amarex Clinical Research \/ Amarex Clinical Research","highestDevelopmentStatusID":"10","companyTruncated":"Amarex Clinical Research \/ Amarex Clinical Research"},{"orgOrder":0,"company":"Amarex Clinical Research","sponsor":"CytoDyn","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Antibody, Unconjugated","year":"2014","type":"Inapplicable","leadProduct":"Leronlimab","moa":"C-C chemokine receptor type 5","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"Amarex Clinical Research","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Injection","sponsorNew":"Amarex Clinical Research \/ Amarex Clinical Research","highestDevelopmentStatusID":"10","companyTruncated":"Amarex Clinical Research \/ Amarex Clinical Research"},{"orgOrder":0,"company":"Amarex Clinical Research","sponsor":"CytoDyn","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"U.S.A","productType":"Antibody, Unconjugated","year":"2016","type":"Inapplicable","leadProduct":"Leronlimab","moa":"C-C chemokine receptor type 5","graph1":"Immunology","graph2":"Phase II","graph3":"Amarex Clinical Research","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Amarex Clinical Research \/ Amarex Clinical Research","highestDevelopmentStatusID":"8","companyTruncated":"Amarex Clinical Research \/ Amarex Clinical Research"},{"orgOrder":0,"company":"Amarex Clinical Research","sponsor":"CytoDyn","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Antibody, Unconjugated","year":"2023","type":"Inapplicable","leadProduct":"Leronlimab","moa":"C-C chemokine receptor type 5","graph1":"Genetic Disease","graph2":"Phase II","graph3":"Amarex Clinical Research","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Amarex Clinical Research \/ Amarex Clinical Research","highestDevelopmentStatusID":"8","companyTruncated":"Amarex Clinical Research \/ Amarex Clinical Research"},{"orgOrder":0,"company":"Amarex Clinical Research","sponsor":"CytoDyn","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody, Unconjugated","year":"2019","type":"Inapplicable","leadProduct":"Leronlimab","moa":"C-C chemokine receptor type 5","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Amarex Clinical Research","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Amarex Clinical Research \/ Amarex Clinical Research","highestDevelopmentStatusID":"7","companyTruncated":"Amarex Clinical Research \/ Amarex Clinical Research"},{"orgOrder":0,"company":"Amarex Clinical Research","sponsor":"CytoDyn","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Antibody, Unconjugated","year":"2016","type":"Inapplicable","leadProduct":"Leronlimab","moa":"C-C chemokine receptor type 5","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"Amarex Clinical Research","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Amarex Clinical Research \/ Amarex Clinical Research","highestDevelopmentStatusID":"10","companyTruncated":"Amarex Clinical Research \/ Amarex Clinical Research"},{"orgOrder":0,"company":"Amarex Clinical Research","sponsor":"Amarex Clinical Research","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"FRANCE","productType":"Peptide, Unconjugated","year":"2020","type":"Inapplicable","leadProduct":"Interleukin-7","moa":"IL-7R","graph1":"Infections and Infectious Diseases","graph2":"Phase II","graph3":"Amarex Clinical Research","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Amarex Clinical Research \/ Amarex Clinical Research","highestDevelopmentStatusID":"8","companyTruncated":"Amarex Clinical Research \/ Amarex Clinical Research"},{"orgOrder":0,"company":"Amarex Clinical Research","sponsor":"Amytrx Therapeutics","pharmaFlowCategory":"DU","therapeuticArea":"Dermatology","country":"U.S.A","productType":"Peptide, Unconjugated","year":"2022","type":"Inapplicable","leadProduct":"AMTX-100","moa":"NFkB","graph1":"Dermatology","graph2":"Phase I\/ Phase II","graph3":"Amarex Clinical Research","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Cream","sponsorNew":"Amarex Clinical Research \/ Amarex Clinical Research","highestDevelopmentStatusID":"7","companyTruncated":"Amarex Clinical Research \/ Amarex Clinical Research"},{"orgOrder":0,"company":"Amarex Clinical Research","sponsor":"Amytrx Therapeutics","pharmaFlowCategory":"DU","therapeuticArea":"Dermatology","country":"U.S.A","productType":"Peptide, Unconjugated","year":"2023","type":"Inapplicable","leadProduct":"AMTX-100","moa":"NFkB","graph1":"Dermatology","graph2":"Phase I\/ Phase II","graph3":"Amarex Clinical Research","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Cream","sponsorNew":"Amarex Clinical Research \/ Amarex Clinical Research","highestDevelopmentStatusID":"7","companyTruncated":"Amarex Clinical Research \/ Amarex Clinical Research"},{"orgOrder":0,"company":"Amarex Clinical Research","sponsor":"Sirnaomics","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Oligonucleotide","year":"2020","type":"Inapplicable","leadProduct":"STP705","moa":"TGF-beta-1\/COX-2","graph1":"Oncology","graph2":"Phase II","graph3":"Amarex Clinical Research","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Powder","sponsorNew":"Amarex Clinical Research \/ Amarex Clinical Research","highestDevelopmentStatusID":"8","companyTruncated":"Amarex Clinical Research \/ Amarex Clinical Research"},{"orgOrder":0,"company":"Amarex Clinical Research","sponsor":"Sirnaomics","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Oligonucleotide","year":"2020","type":"Inapplicable","leadProduct":"STP705","moa":"TGF-beta-1\/COX-2","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Amarex Clinical Research","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Amarex Clinical Research \/ Amarex Clinical Research","highestDevelopmentStatusID":"7","companyTruncated":"Amarex Clinical Research \/ Amarex Clinical Research"},{"orgOrder":0,"company":"Amarex Clinical Research","sponsor":"Aim ImmunoTech","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Oligonucleotide","year":"2022","type":"Inapplicable","leadProduct":"Rintatolimod","moa":"Toll-like receptor 3","graph1":"Oncology","graph2":"Phase II","graph3":"Amarex Clinical Research","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Amarex Clinical Research \/ Amarex Clinical Research","highestDevelopmentStatusID":"8","companyTruncated":"Amarex Clinical Research \/ Amarex Clinical Research"},{"orgOrder":0,"company":"Amarex Clinical Research","sponsor":"Aim 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Diseases","graph2":"Phase II","graph3":"Amarex Clinical Research","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Amarex Clinical Research \/ Amarex Clinical Research","highestDevelopmentStatusID":"8","companyTruncated":"Amarex Clinical Research \/ Amarex Clinical Research"},{"orgOrder":0,"company":"Amarex Clinical Research","sponsor":"Amarex Clinical Research","pharmaFlowCategory":"DU","therapeuticArea":"Podiatry","country":"","productType":"Cell & Gene Therapy","year":"2025","type":"Inapplicable","leadProduct":"Amnio Matrix","moa":"Undisclosed","graph1":"Podiatry","graph2":"Undisclosed","graph3":"Amarex Clinical Research","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Podiatry","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Amarex Clinical Research \/ Amarex Clinical Research","highestDevelopmentStatusID":"1","companyTruncated":"Amarex Clinical Research \/ Amarex Clinical Research"},{"orgOrder":0,"company":"Amarex Clinical Research","sponsor":"Amytrx Therapeutics","pharmaFlowCategory":"DU","therapeuticArea":"Dermatology","country":"U.S.A","productType":"Undisclosed","year":"2020","type":"Inapplicable","leadProduct":"AMTX-100 CF","moa":"Undisclosed","graph1":"Dermatology","graph2":"Phase I\/ Phase II","graph3":"Amarex Clinical Research","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Cream","sponsorNew":"Amarex Clinical Research \/ Amarex Clinical Research","highestDevelopmentStatusID":"7","companyTruncated":"Amarex Clinical Research \/ Amarex Clinical Research"},{"orgOrder":0,"company":"Amarex Clinical Research","sponsor":"Amarantus BioScience Holdings","pharmaFlowCategory":"DU","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"U.S.A","productType":"Cell & Gene Therapy","year":"2012","type":"Inapplicable","leadProduct":"Autologous Engineered Skin Substitute","moa":"Undisclosed","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"Phase II","graph3":"Amarex Clinical Research","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Sheet","sponsorNew":"Amarex Clinical Research \/ Amarex Clinical Research","highestDevelopmentStatusID":"8","companyTruncated":"Amarex Clinical Research \/ Amarex Clinical Research"},{"orgOrder":0,"company":"Amarex Clinical Research","sponsor":"Amarex Clinical Research","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"","productType":"Undisclosed","year":"2023","type":"Inapplicable","leadProduct":"MT101-5","moa":"Undisclosed","graph1":"Neurology","graph2":"Phase II","graph3":"Amarex Clinical Research","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Amarex Clinical Research \/ Amarex Clinical Research","highestDevelopmentStatusID":"8","companyTruncated":"Amarex Clinical Research \/ Amarex Clinical Research"},{"orgOrder":0,"company":"Amarex Clinical Research","sponsor":"Amarex Clinical Research","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"CHINA","productType":"Miscellaneous","year":"2020","type":"Inapplicable","leadProduct":"Progerinin","moa":"Undisclosed","graph1":"Genetic Disease","graph2":"Phase II","graph3":"Amarex Clinical Research","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Suspension","sponsorNew":"Amarex Clinical Research \/ Amarex Clinical Research","highestDevelopmentStatusID":"8","companyTruncated":"Amarex Clinical Research \/ Amarex Clinical Research"},{"orgOrder":0,"company":"Amarex Clinical Research","sponsor":"Allarity Therapeutics","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"DENMARK","productType":"Undisclosed","year":"2022","type":"Inapplicable","leadProduct":"X-121","moa":"Undisclosed","graph1":"Oncology","graph2":"Phase I","graph3":"Amarex Clinical Research","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Amarex Clinical Research \/ Amarex Clinical Research","highestDevelopmentStatusID":"6","companyTruncated":"Amarex Clinical Research \/ Amarex Clinical Research"}]

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Amnio Matrix is a Cell and Gene therapy drug candidate, which is currently being evaluated in clinical studies for the treatment of Diabetic Foot.

                          Product Name : Undisclosed

                          Product Type : Cell & Gene Therapy

                          Upfront Cash : Inapplicable

                          August 11, 2025

                          Lead Product(s) : Amnio Matrix

                          Therapeutic Area : Podiatry

                          Highest Development Status : Undisclosed

                          Recipient : New Horizon Medical Solutions

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Ampligen® (rintatolimod) is an immuno-modulator with broad spectrum activity and evaluating Phase 2 Study for the Treatment of people with post-COVID conditions.

                          Product Name : Ampligen

                          Product Type : Oligonucleotide

                          Upfront Cash : Inapplicable

                          July 10, 2023

                          Lead Product(s) : Rintatolimod

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Recipient : Aim ImmunoTech

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : AMTX-100 CF3, is a topical formulation anti-inflammatory peptide therapeutic designed to treat patients suffering from mild to moderate atopic dermatitis.

                          Product Name : Undisclosed

                          Product Type : Peptide, Unconjugated

                          Upfront Cash : Inapplicable

                          June 28, 2023

                          Lead Product(s) : AMTX-100

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase I/ Phase II

                          Recipient : Amytrx Therapeutics

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : MT101-5 is a drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Parkinson Disease.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Inapplicable

                          May 06, 2023

                          Lead Product(s) : MT101-5

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase I

                          Recipient : Mthera Pharma

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Leronlimab is a Antibody drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Microsatellite Instability.

                          Product Name : Undisclosed

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Inapplicable

                          February 16, 2023

                          Lead Product(s) : Leronlimab

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase II

                          Recipient : CytoDyn

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Rintatolimod is a Oligonucleotide drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Post-Acute COVID-19 Syndrome.

                          Product Name : Undisclosed

                          Product Type : Oligonucleotide

                          Upfront Cash : Inapplicable

                          October 24, 2022

                          Lead Product(s) : Rintatolimod

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Recipient : Aim ImmunoTech

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : X-121 is a drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Neoplasms.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Inapplicable

                          October 07, 2022

                          Lead Product(s) : X-121

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Recipient : Allarity Therapeutics

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Rintatolimod is a Oligonucleotide drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Pancreatic Neoplasms.

                          Product Name : Undisclosed

                          Product Type : Oligonucleotide

                          Upfront Cash : Inapplicable

                          August 10, 2022

                          Lead Product(s) : Rintatolimod

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Recipient : Aim ImmunoTech

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : AMTX-100 CF3, its leading drug candidate, is known for its ability to transport across membranes, address inflammation and modulate immune mediated diseases instead of simply inhibiting inflammation.

                          Product Name : Undisclosed

                          Product Type : Peptide, Unconjugated

                          Upfront Cash : Inapplicable

                          June 09, 2022

                          Lead Product(s) : AMTX-100

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase I/ Phase II

                          Recipient : Amytrx Therapeutics

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Leronlimab is a Antibody drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of COVID-19.

                          Product Name : Undisclosed

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Inapplicable

                          December 22, 2020

                          Lead Product(s) : Leronlimab

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Recipient : CytoDyn

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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