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Find Clinical Drug Pipeline Developments & Deals by AMAG Pharmaceuticals

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                          Top Deals by Deal Size (USD bn)

                          01

                          Pharmaconex
                          Not Confirmed
                          Pharmaconex
                          Not Confirmed

                          Details : Makena (hydroxyprogesterone caproate) is a synthetic progestin. The drug was approved to reduce the risk of preterm birth in women pregnant with one baby who have a history of spontaneous preterm birth. It has been withdrawn and cannot lawfully be distri...

                          Product Name : Makena

                          Product Type : Hormone

                          Upfront Cash : Inapplicable

                          June 04, 2023

                          Lead Product(s) : Hydroxyprogesterone Caproate

                          Therapeutic Area : Obstetrics/Gynecology (Women’s Health)

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          Pharmaconex
                          Not Confirmed
                          Pharmaconex
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          June 01, 2021

                          Lead Product(s) : Aspirin

                          Therapeutic Area : Obstetrics/Gynecology (Women’s Health)

                          Highest Development Status : Phase IV

                          Recipient : Eastern Virginia Medical School

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          Pharmaconex
                          Not Confirmed
                          Pharmaconex
                          Not Confirmed

                          Details : FDA’s Notice of Opportunity for a Hearing regarding the Agency’s proposal to withdraw approval for Makena also referred to as 17-OHPC, to reduce preterm birth in women with a singleton pregnancy who have a history of singleton spontaneous preterm bir...

                          Product Name : Makena

                          Product Type : Hormone

                          Upfront Cash : Inapplicable

                          December 14, 2020

                          Lead Product(s) : Hydroxyprogesterone Caproate

                          Therapeutic Area : Obstetrics/Gynecology (Women’s Health)

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          Pharmaconex
                          Not Confirmed
                          Pharmaconex
                          Not Confirmed

                          Details : Results from both studies, which randomized a total of 113 subjects, showed that steady-state anticoagulation induced by apixaban or rivaroxaban was reversed by a single IV infusion of ciraparantag in a dose-related manner as assessed by whole blood clot...

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          December 07, 2020

                          Lead Product(s) : Ciraparantag

                          Therapeutic Area : Hematology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          Pharmaconex
                          Not Confirmed
                          Pharmaconex
                          Not Confirmed

                          Details : The acquisition adds AMAG's key products Feraheme®, Makena® and Ciraparantag to Covis' pipeline as it carries out its mission of expanding patient access to much needed therapies.

                          Product Name : Feraheme

                          Product Type : Vitamins/Minerals/Inorganic Salts

                          Upfront Cash : $647.0 million

                          November 16, 2020

                          Lead Product(s) : Ferumoxytol

                          Therapeutic Area : Hematology

                          Highest Development Status : Approved FDF

                          Sponsor : Covis Pharma

                          Deal Size : $647.0 million

                          Deal Type : Acquisition

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                          06

                          Pharmaconex
                          Not Confirmed
                          Pharmaconex
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          October 20, 2020

                          Lead Product(s) : Ciraparantag

                          Therapeutic Area : Undisclosed

                          Highest Development Status : Phase II

                          Sponsor : Ciraparantag Holdings

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          Pharmaconex
                          Not Confirmed
                          Pharmaconex
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          July 30, 2020

                          Lead Product(s) : Dehydroepiandrosterone

                          Therapeutic Area : Obstetrics/Gynecology (Women’s Health)

                          Highest Development Status : Phase II

                          Recipient : University of Arkansas

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          Pharmaconex
                          Not Confirmed
                          Pharmaconex
                          Not Confirmed

                          Details : Under the terms of the termination agreement, all of AMAG’s rights and obligations to develop and commercialize Vyleesi under the license agreement will terminate, and full ownership of Vyleesi will transfer back to Palatin.

                          Product Name : Vyleesi

                          Product Type : Peptide

                          Upfront Cash : $12.0 million

                          July 27, 2020

                          Lead Product(s) : Bremelanotide Acetate

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Approved FDF

                          Recipient : Palatin Technologies

                          Deal Size : $16.3 million

                          Deal Type : Divestment

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                          09

                          Pharmaconex
                          Not Confirmed
                          Pharmaconex
                          Not Confirmed

                          Details : Ciraparantag is in development for use in patients treated with direct oral anticoagulants and low molecular weight heparin when reversal of the anticoagulant effect of these products is needed for emergency surgery or due to life-threatening or uncontro...

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : $30.0 million

                          July 23, 2020

                          Lead Product(s) : Ciraparantag

                          Therapeutic Area : Hematology

                          Highest Development Status : Phase II

                          Sponsor : Norgine

                          Deal Size : $290.0 million

                          Deal Type : Licensing Agreement

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                          10

                          Pharmaconex
                          Not Confirmed
                          Pharmaconex
                          Not Confirmed

                          Details : Transaction allows AMAG to advance its strategic focus on Feraheme, Makena and its pipeline, consistent with previously announced plans.

                          Product Name : Intrarosa

                          Product Type : Hormone

                          Upfront Cash : $20.0 million

                          May 21, 2020

                          Lead Product(s) : Prasterone

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved FDF

                          Sponsor : Millicent Pharma

                          Deal Size : $125.0 million

                          Deal Type : Divestment

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