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    [{"orgOrder":0,"company":"Allena Pharmaceuticals","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Nephrology","country":"U.S.A","productType":"Enzyme","year":"2020","type":"Inapplicable","leadProduct":"Reloxaliase","moa":"Oxalate","graph1":"Nephrology","graph2":"Phase III","graph3":"Allena Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Allena Pharmaceuticals \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Allena Pharmaceuticals \/ Undisclosed"},{"orgOrder":0,"company":"Allena Pharmaceuticals","sponsor":"H.C. 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                            01

                            Allena Pharmaceuticals

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                            Lead Product(s) : ALLN-346

                            Therapeutic Area : Rheumatology

                            Study Phase : Phase I

                            Sponsor : BDD Pharma

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Scintigraphy Study in Healthy Volunteers to Characterize the Performance of ALLN-346 Tablets

                            Details : ALLN-346 is a Enzyme drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Hyperuricemia.

                            Product Name : Undisclosed

                            Product Type : Enzyme

                            Upfront Cash : Inapplicable

                            December 23, 2021

                            Lead Product(s) : ALLN-346

                            Therapeutic Area : Rheumatology

                            Highest Development Status : Phase I

                            Sponsor : BDD Pharma

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Allena Pharmaceuticals

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                            Allena Pharmaceuticals

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                            Lead Product(s) : Engineered Urate Oxidase

                            Therapeutic Area : Rheumatology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Allena Pharmaceuticals Receives Fast Track Designation from FDA for the Development of ALLN-346 for Chronic Tr...

                            Details : Company is developing ALLN-346 for the treatment of hyperuricemia and gout in the setting of advanced CKD, with a Phase 1 multiple ascending dose study recently completed and a Phase 2a program underway.

                            Product Name : Undisclosed

                            Product Type : Enzyme

                            Upfront Cash : Inapplicable

                            November 03, 2021

                            Lead Product(s) : Engineered Urate Oxidase

                            Therapeutic Area : Rheumatology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Allena Pharmaceuticals

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                            Lead Product(s) : Engineered Urate Oxidase

                            Therapeutic Area : Rheumatology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Allena Pharmaceuticals Commences Dosing of Gout Patients in Second Phase 2a Trial of ALLN-346

                            Details : Allena recently completed a Phase 1b multiple ascending dose study of ALLN-346. The study included 18 healthy volunteers, who received either ALLN-346 or placebo (2:1 randomization) for seven days.

                            Product Name : Undisclosed

                            Product Type : Enzyme

                            Upfront Cash : Inapplicable

                            September 29, 2021

                            Lead Product(s) : Engineered Urate Oxidase

                            Therapeutic Area : Rheumatology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Allena Pharmaceuticals

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                            Lead Product(s) : ALLN-346

                            Therapeutic Area : Rheumatology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            An Inpatient Study of ALLN-346 (Engineered Urate Oxidase) in Hyperuricemic Subjects (Study 201)

                            Details : ALLN-346 is a Enzyme drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Hyperuricemia.

                            Product Name : Undisclosed

                            Product Type : Enzyme

                            Upfront Cash : Inapplicable

                            August 03, 2021

                            Lead Product(s) : ALLN-346

                            Therapeutic Area : Rheumatology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Allena Pharmaceuticals

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                            Allena Pharmaceuticals

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                            Lead Product(s) : ALLN-346

                            Therapeutic Area : Rheumatology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Phase IIa Study of ALLN-346 (Engineered Urate Oxidase) in Subjects With Hyperuricemia, Gout and Chronic Kidney...

                            Details : ALLN-346 is a Enzyme drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Hyperuricemia.

                            Product Name : Undisclosed

                            Product Type : Enzyme

                            Upfront Cash : Inapplicable

                            August 03, 2021

                            Lead Product(s) : ALLN-346

                            Therapeutic Area : Rheumatology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Allena Pharmaceuticals

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                            Lead Product(s) : Reloxaliase

                            Therapeutic Area : Gastroenterology

                            Study Phase : Phase III

                            Sponsor : H.C. Wainwright & Co

                            Deal Size : $28.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Allena Pharmaceuticals Announces $28 Million Registered Direct Offering Priced At-the-Market under Nasdaq Rule...

                            Details : Allena’s lead product candidate, reloxaliase (formerly ALLN-177), is a first-in-class, non-absorbed, orally-administered enzyme for the treatment of hyperoxaluria.

                            Product Name : Undisclosed

                            Product Type : Enzyme

                            Upfront Cash : Undisclosed

                            July 14, 2021

                            Lead Product(s) : Reloxaliase

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Phase III

                            Sponsor : H.C. Wainwright & Co

                            Deal Size : $28.0 million

                            Deal Type : Public Offering

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                            07

                            Allena Pharmaceuticals

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                            Lead Product(s) : ALLN-346

                            Therapeutic Area : Rheumatology

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Study 102: Multiple Ascending Dose Study of ALLN-346 (Engineered Urate Oxidase)

                            Details : ALLN-346 is a Enzyme drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Hyperuricemia.

                            Product Name : Undisclosed

                            Product Type : Enzyme

                            Upfront Cash : Inapplicable

                            April 02, 2021

                            Lead Product(s) : ALLN-346

                            Therapeutic Area : Rheumatology

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Allena Pharmaceuticals

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                            Lead Product(s) : Reloxaliase

                            Therapeutic Area : Nephrology

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Allena Pharmaceuticals Announces Streamlined Design for URIROX-2

                            Details : Allena now plans to reducing target enrollment to 200 subjects. Conducting earlier interim analysis, expected in Q3 2021.

                            Product Name : Undisclosed

                            Product Type : Enzyme

                            Upfront Cash : Inapplicable

                            February 12, 2020

                            Lead Product(s) : Reloxaliase

                            Therapeutic Area : Nephrology

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Allena Pharmaceuticals

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                            Lead Product(s) : ALLN-346

                            Therapeutic Area : Rheumatology

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            ALLN-346 Single Ascending Dose (SAD) Study in Healthy Volunteers

                            Details : ALLN-346 is a Enzyme drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Hyperuricemia.

                            Product Name : Undisclosed

                            Product Type : Enzyme

                            Upfront Cash : Inapplicable

                            January 22, 2020

                            Lead Product(s) : ALLN-346

                            Therapeutic Area : Rheumatology

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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