
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : ALLN-346
Therapeutic Area : Rheumatology
Study Phase : Phase I
Sponsor : BDD Pharma
Deal Size : Inapplicable
Deal Type : Inapplicable
Scintigraphy Study in Healthy Volunteers to Characterize the Performance of ALLN-346 Tablets
Details : ALLN-346 is a Enzyme drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Hyperuricemia.
Product Name : Undisclosed
Product Type : Enzyme
Upfront Cash : Inapplicable
December 23, 2021
Lead Product(s) : ALLN-346
Therapeutic Area : Rheumatology
Highest Development Status : Phase I
Sponsor : BDD Pharma
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Engineered Urate Oxidase
Therapeutic Area : Rheumatology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Company is developing ALLN-346 for the treatment of hyperuricemia and gout in the setting of advanced CKD, with a Phase 1 multiple ascending dose study recently completed and a Phase 2a program underway.
Product Name : Undisclosed
Product Type : Enzyme
Upfront Cash : Inapplicable
November 03, 2021
Lead Product(s) : Engineered Urate Oxidase
Therapeutic Area : Rheumatology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Engineered Urate Oxidase
Therapeutic Area : Rheumatology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Allena Pharmaceuticals Commences Dosing of Gout Patients in Second Phase 2a Trial of ALLN-346
Details : Allena recently completed a Phase 1b multiple ascending dose study of ALLN-346. The study included 18 healthy volunteers, who received either ALLN-346 or placebo (2:1 randomization) for seven days.
Product Name : Undisclosed
Product Type : Enzyme
Upfront Cash : Inapplicable
September 29, 2021
Lead Product(s) : Engineered Urate Oxidase
Therapeutic Area : Rheumatology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : ALLN-346
Therapeutic Area : Rheumatology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
An Inpatient Study of ALLN-346 (Engineered Urate Oxidase) in Hyperuricemic Subjects (Study 201)
Details : ALLN-346 is a Enzyme drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Hyperuricemia.
Product Name : Undisclosed
Product Type : Enzyme
Upfront Cash : Inapplicable
August 03, 2021
Lead Product(s) : ALLN-346
Therapeutic Area : Rheumatology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : ALLN-346
Therapeutic Area : Rheumatology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ALLN-346 is a Enzyme drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Hyperuricemia.
Product Name : Undisclosed
Product Type : Enzyme
Upfront Cash : Inapplicable
August 03, 2021
Lead Product(s) : ALLN-346
Therapeutic Area : Rheumatology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Reloxaliase
Therapeutic Area : Gastroenterology
Study Phase : Phase III
Sponsor : H.C. Wainwright & Co
Deal Size : $28.0 million
Deal Type : Public Offering
Details : Allena’s lead product candidate, reloxaliase (formerly ALLN-177), is a first-in-class, non-absorbed, orally-administered enzyme for the treatment of hyperoxaluria.
Product Name : Undisclosed
Product Type : Enzyme
Upfront Cash : Undisclosed
July 14, 2021
Lead Product(s) : Reloxaliase
Therapeutic Area : Gastroenterology
Highest Development Status : Phase III
Sponsor : H.C. Wainwright & Co
Deal Size : $28.0 million
Deal Type : Public Offering

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Lead Product(s) : ALLN-346
Therapeutic Area : Rheumatology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Study 102: Multiple Ascending Dose Study of ALLN-346 (Engineered Urate Oxidase)
Details : ALLN-346 is a Enzyme drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Hyperuricemia.
Product Name : Undisclosed
Product Type : Enzyme
Upfront Cash : Inapplicable
April 02, 2021
Lead Product(s) : ALLN-346
Therapeutic Area : Rheumatology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Reloxaliase
Therapeutic Area : Nephrology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Allena Pharmaceuticals Announces Streamlined Design for URIROX-2
Details : Allena now plans to reducing target enrollment to 200 subjects. Conducting earlier interim analysis, expected in Q3 2021.
Product Name : Undisclosed
Product Type : Enzyme
Upfront Cash : Inapplicable
February 12, 2020
Lead Product(s) : Reloxaliase
Therapeutic Area : Nephrology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : ALLN-346
Therapeutic Area : Rheumatology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
ALLN-346 Single Ascending Dose (SAD) Study in Healthy Volunteers
Details : ALLN-346 is a Enzyme drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Hyperuricemia.
Product Name : Undisclosed
Product Type : Enzyme
Upfront Cash : Inapplicable
January 22, 2020
Lead Product(s) : ALLN-346
Therapeutic Area : Rheumatology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Reloxaliase
Therapeutic Area : Nephrology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Establishing the Safety and Efficacy of Reloxaliase in Patients With Enteric Hyperoxaluria
Details : Reloxaliase is a Enzyme drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Hyperoxaluria.
Product Name : Undisclosed
Product Type : Enzyme
Upfront Cash : Inapplicable
February 20, 2019
Lead Product(s) : Reloxaliase
Therapeutic Area : Nephrology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
