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    [{"orgOrder":0,"company":"Allegro Ophthalmics","sponsor":"Bausch Health","pharmaFlowCategory":"D","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Peptide","year":"2020","type":"Acquisition","leadProduct":"Risuteganib","moa":"angiogenesis inhibitors","graph1":"Ophthalmology","graph2":"Phase II","graph3":"Allegro Ophthalmics","amount2":0.050000000000000003,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Ophthalmology","amount2New":0.050000000000000003,"dosageForm":"Intravitreal Injection","sponsorNew":"Allegro Ophthalmics \/ Bausch Health","highestDevelopmentStatusID":"8","companyTruncated":"Allegro Ophthalmics \/ Bausch Health"},{"orgOrder":0,"company":"Allegro Ophthalmics","sponsor":"Bausch Health","pharmaFlowCategory":"D","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Peptide","year":"2020","type":"Acquisition","leadProduct":"Risuteganib","moa":"angiogenesis inhibitors","graph1":"Ophthalmology","graph2":"Phase II","graph3":"Allegro Ophthalmics","amount2":0.050000000000000003,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Ophthalmology","amount2New":0.050000000000000003,"dosageForm":"Intravitreal Injection","sponsorNew":"Allegro Ophthalmics \/ Bausch Health","highestDevelopmentStatusID":"8","companyTruncated":"Allegro Ophthalmics \/ Bausch Health"},{"orgOrder":0,"company":"Allegro Ophthalmics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Peptide","year":"2023","type":"Inapplicable","leadProduct":"Risuteganib","moa":"angiogenesis inhibitors","graph1":"Ophthalmology","graph2":"Phase II","graph3":"Allegro Ophthalmics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Intravitreal Injection","sponsorNew":"Allegro Ophthalmics \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Allegro Ophthalmics \/ Inapplicable"},{"orgOrder":0,"company":"Allegro Ophthalmics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Peptide","year":"2023","type":"Inapplicable","leadProduct":"Risuteganib","moa":"angiogenesis inhibitors","graph1":"Ophthalmology","graph2":"Phase II","graph3":"Allegro Ophthalmics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Intravitreal Injection","sponsorNew":"Allegro Ophthalmics \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Allegro Ophthalmics \/ Inapplicable"},{"orgOrder":0,"company":"Allegro Ophthalmics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Peptide","year":"2021","type":"Inapplicable","leadProduct":"Risuteganib","moa":"angiogenesis inhibitors","graph1":"Ophthalmology","graph2":"Phase II","graph3":"Allegro Ophthalmics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Intravitreal Injection","sponsorNew":"Allegro Ophthalmics \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Allegro Ophthalmics \/ Inapplicable"}]

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                            01

                            Allegro Ophthalmics

                            U.S.A arrow
                            BIOHK2025
                            Not Confirmed

                            Allegro Ophthalmics

                            U.S.A arrow
                            BIOHK2025
                            Not Confirmed
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                            Lead Product(s) : Risuteganib

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Allegro Ophthalmics Receives FDA Agreement Under Special Protocol Assessment (SPA) for Phase 2b/3 Clinical Tri...

                            Details : Luminate® (risuteganib) is a novel anti-integrin peptide that targets the multiple integrin heterodimers involved in the pathophysiology of dry AMD, it is being investigated for the treatment of intermediate, non-exudative age-related macular degenerati...

                            Product Name : Luminate

                            Product Type : Peptide

                            Upfront Cash : Inapplicable

                            December 04, 2023

                            Lead Product(s) : Risuteganib

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Allegro Ophthalmics

                            U.S.A arrow
                            BIOHK2025
                            Not Confirmed

                            Allegro Ophthalmics

                            U.S.A arrow
                            BIOHK2025
                            Not Confirmed
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                            Lead Product(s) : Risuteganib

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Allegro Ophthalmics Announces Presentation of Key Data Surrounding Dry AMD Pipeline Candidates, Treatment Cons...

                            Details : Pre-clinical data suggest that Luminate (risuteganib), Allegro’s lead investigational compound in retina, may simultaneously act on the angiogenic, inflammatory and mitochondrial metabolic pathways implicated in diseases, such as dry AMD.

                            Product Name : Luminate

                            Product Type : Peptide

                            Upfront Cash : Inapplicable

                            October 02, 2023

                            Lead Product(s) : Risuteganib

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Allegro Ophthalmics

                            U.S.A arrow
                            BIOHK2025
                            Not Confirmed

                            Allegro Ophthalmics

                            U.S.A arrow
                            BIOHK2025
                            Not Confirmed
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                            Lead Product(s) : Risuteganib

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            U.S. Phase 2 Study Published in OSLI Retina Highlights the Safety and Efficacy of Risuteganib in Dry Age-Relat...

                            Details : These clinical data suggest that risuteganib can reverse vision loss and restore functional vision in patients with intermediate dry AMD with treatment at a 12-week interval.

                            Product Name : Luminate

                            Product Type : Peptide

                            Upfront Cash : Inapplicable

                            March 08, 2021

                            Lead Product(s) : Risuteganib

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Allegro Ophthalmics

                            U.S.A arrow
                            BIOHK2025
                            Not Confirmed

                            Allegro Ophthalmics

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                            BIOHK2025
                            Not Confirmed
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                            Lead Product(s) : Risuteganib

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase II

                            Sponsor : Bausch Health

                            Deal Size : $50.0 million

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Bausch Health To Acquire Option To Purchase All Ophthalmology Assets Of Allegro Ophthalmics

                            Details : Bausch Health, has entered into an agreement to acquire an option to purchase all ophthalmology assets of Allegro, including global rights for risuteganib (Luminate). Allegro include ALG-1007, a topical integrin regulator under investigation for treatmen...

                            Product Name : Luminate

                            Product Type : Peptide

                            Upfront Cash : Undisclosed

                            September 21, 2020

                            Lead Product(s) : Risuteganib

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase II

                            Sponsor : Bausch Health

                            Deal Size : $50.0 million

                            Deal Type : Acquisition

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                            05

                            Allegro Ophthalmics

                            U.S.A arrow
                            BIOHK2025
                            Not Confirmed

                            Allegro Ophthalmics

                            U.S.A arrow
                            BIOHK2025
                            Not Confirmed
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                            Lead Product(s) : Risuteganib

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase II

                            Sponsor : Bausch Health

                            Deal Size : $50.0 million

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Bausch Health To Acquire Option To Purchase All Ophthalmology Assets Of Allegro Ophthalmics

                            Details : The agreement provides Bausch with global rights for risuteganib, Allegro's lead investigational compound in retina, including Other ophthalmology assets such as Allegro's ALG-1007, a topical integrin regulator under investigation for the treatment of dr...

                            Product Name : Luminate

                            Product Type : Peptide

                            Upfront Cash : $10.0 million

                            September 21, 2020

                            Lead Product(s) : Risuteganib

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase II

                            Sponsor : Bausch Health

                            Deal Size : $50.0 million

                            Deal Type : Acquisition

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                            06

                            Allegro Ophthalmics

                            U.S.A arrow
                            BIOHK2025
                            Not Confirmed

                            Allegro Ophthalmics

                            U.S.A arrow
                            BIOHK2025
                            Not Confirmed
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                            Lead Product(s) : Risuteganib

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Clinical Trial Designed To Evaluate The Safety And Exploratory Efficacy Of 1.0 Mg Luminate® (Alg-1001) As...

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Peptide

                            Upfront Cash : Inapplicable

                            August 13, 2018

                            Lead Product(s) : Risuteganib

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Allegro Ophthalmics

                            U.S.A arrow
                            BIOHK2025
                            Not Confirmed

                            Allegro Ophthalmics

                            U.S.A arrow
                            BIOHK2025
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Risuteganib

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase II

                            Sponsor : Duke University | Trial Runners, LLC

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Clinical Trial Designed to Evaluate the Safety and Efficacy Study of Luminate® in Inducing PVD (Posterior...

                            Details : Undisclosed

                            Product Name : Luminate

                            Product Type : Peptide

                            Upfront Cash : Inapplicable

                            May 06, 2015

                            Lead Product(s) : Risuteganib

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase II

                            Sponsor : Duke University | Trial Runners, LLC

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Allegro Ophthalmics

                            U.S.A arrow
                            BIOHK2025
                            Not Confirmed

                            Allegro Ophthalmics

                            U.S.A arrow
                            BIOHK2025
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Risuteganib

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase II

                            Sponsor : Trial Runners, LLC | Duke University

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Phase 2 Randomized Clinical Trial of Luminate® as Compared to Avastin® in the Treatment of Diabetic Macu...

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Peptide

                            Upfront Cash : Inapplicable

                            January 28, 2015

                            Lead Product(s) : Risuteganib

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase II

                            Sponsor : Trial Runners, LLC | Duke University

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Allegro Ophthalmics

                            U.S.A arrow
                            BIOHK2025
                            Not Confirmed

                            Allegro Ophthalmics

                            U.S.A arrow
                            BIOHK2025
                            Not Confirmed
                            • fda
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                            Lead Product(s) : Risuteganib

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Safety And Efficacy Study Of Alg-1001 In Human Subjects With Symptomatic Focal Vitreomacular Adhesion

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Peptide

                            Upfront Cash : Inapplicable

                            June 03, 2014

                            Lead Product(s) : Risuteganib

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Allegro Ophthalmics

                            U.S.A arrow
                            BIOHK2025
                            Not Confirmed

                            Allegro Ophthalmics

                            U.S.A arrow
                            BIOHK2025
                            Not Confirmed
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                            Lead Product(s) : Risuteganib

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Safety And Efficacy Study Of ALG-1001 In Human Subjects With Wet Age-Related Macular Degeneration

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Peptide

                            Upfront Cash : Inapplicable

                            December 17, 2012

                            Lead Product(s) : Risuteganib

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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