
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : Bupivacaine
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Lightstone Ventures
Deal Size : $57.5 million
Deal Type : Series D Financing
Allay Announces $57.5M Series D Financing and Venture Debt Line
Details : The proceeds will be used to advance ATX101, a novel investigational configuration of an approved, well-characterized, validated intracellular sodium ion channel blocker, bupivacaine.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
June 05, 2025
Lead Product(s) : Bupivacaine
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Lightstone Ventures
Deal Size : $57.5 million
Deal Type : Series D Financing

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Lead Product(s) : Bupivacaine
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Allay Announces First Patients Dosed in Pivotal Phase 2b of ATX101
Details : ATX101 is a novel validated intracellular sodium ion channel blocker, bupivacaine, and a biopolymer that has been designed to provide weeks of pain relief following total knee arthroplasty.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
February 18, 2025
Lead Product(s) : Bupivacaine
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Deoxycholic Acid
Therapeutic Area : Undisclosed
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Study Assessing Pain Relief After Replacement of the Knee
Details : Deoxycholic acid is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of undefined medical condition.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
January 29, 2025
Lead Product(s) : Deoxycholic Acid
Therapeutic Area : Undisclosed
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Bupivacaine
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Allay Therapeutics: IND Accepted for Pivotal Phase 2B Trial of ATX101
Details : ATX101 is a novel validated intracellular sodium ion channel blocker, bupivacaine, and a biopolymer that has been designed to provide weeks of pain relief following total knee arthroplasty.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
June 12, 2024
Lead Product(s) : Bupivacaine
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Bupivacaine
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Allay Therapeutics’ Phase 2B Study Supports ATX101 for Post-surgical Pain
Details : ATX101 is an investigational configuration of bupivacaine, designed to provide weeks of pain relief following total knee arthroplasty as a sodium ion channel blocker.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
April 11, 2024
Lead Product(s) : Bupivacaine
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Bupivacaine
Therapeutic Area : Orthopedics/Orthopedic Surgery
Study Phase : Phase II
Sponsor : Maruishi Pharmaceutical
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : Under the agreement, Maruishi will have the exclusive rights to develop and commercialize Allay’s lead investigational drug candidate, ATX101, a non-opioid, bupivacaine-based drug product, and other ultra-sustained analgesic implantable drug candidates...
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
December 18, 2023
Lead Product(s) : Bupivacaine
Therapeutic Area : Orthopedics/Orthopedic Surgery
Highest Development Status : Phase II
Sponsor : Maruishi Pharmaceutical
Deal Size : Undisclosed
Deal Type : Licensing Agreement

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Lead Product(s) : Bupivacaine
Therapeutic Area : Neurology
Study Phase : Phase II
Recipient : Evonik
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ATX-101 is a small product placed directly into the TKA surgical site in a simple, ‘place & go’ manner designed to add minimal extra complexity and time to the procedure.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
December 13, 2022
Lead Product(s) : Bupivacaine
Therapeutic Area : Neurology
Highest Development Status : Phase II
Recipient : Evonik
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Deoxycholic Acid
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Study Assessing Pain Relief After Replacement of the Knee
Details : Deoxycholic acid is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Pain, Postoperative.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
March 02, 2022
Lead Product(s) : Deoxycholic Acid
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Bupivacaine
Therapeutic Area : Orthopedics/Orthopedic Surgery
Study Phase : Phase II
Sponsor : Arboretum Ventures
Deal Size : $60.0 million
Deal Type : Series C Financing
Allay Therapeutics Completes Oversubscribed $60M Financing to Advance Ultra-Sustained Pain Platform
Details : Allay intends to proceed into a Phase 2b study of ATX-101 in total knee arthroplasties (TKA, also called total knee replacements) in the United States.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
September 15, 2021
Lead Product(s) : Bupivacaine
Therapeutic Area : Orthopedics/Orthopedic Surgery
Highest Development Status : Phase II
Sponsor : Arboretum Ventures
Deal Size : $60.0 million
Deal Type : Series C Financing

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Lead Product(s) : Bupivacaine
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ATX-101 is a novel configuration of an approved, well-characterized, validated intracellular sodium ion channel blocker, bupivacaine, and a biopolymer that has been designed to provide weeks of pain relief following total knee arthroplasty.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
May 13, 2021
Lead Product(s) : Bupivacaine
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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