

Alector Shares AL002 Phase 2 Data in Early Alzheimer’s Disease
Details : AL002 is a humanized monoclonal antibody that targets the triggering receptor expressed on myeloid cells 2 (TREM2). It was being investigated for early Alzheimer’s disease.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
November 26, 2024

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Lead Product(s) : AL002
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : AbbVie Inc
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : AL002 is a Antibody drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Alzheimer Disease.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
February 27, 2023
Lead Product(s) : AL002
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : AbbVie Inc
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : AL002
Therapeutic Area : Neurology
Study Phase : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : AL002 is a patented method using a mutant-peptide sensitized cell as a cell-based therapeutic vaccine that reduces beta-amyloid plaque and seeks to restore the ability of the patient’s immunological system to combat Alzheimer’s disease.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
September 30, 2021
Lead Product(s) : AL002
Therapeutic Area : Neurology
Highest Development Status : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : AL002
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : A five-dose GLP study with AL002-sensitized cells was completed using a transgenic (or genetically modified) mouse model of Alzheimer’s disease to investigate the tolerability of AL002.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
July 23, 2021
Lead Product(s) : AL002
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : AL002
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : AbbVie Inc
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : AL002 is an investigational humanized monoclonal antibody that targets triggering receptor expressed on myeloid cells 2 (TREM2) with the most important genetic links to sporadic Alzheimer’s disease.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
January 25, 2021
Lead Product(s) : AL002
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : AbbVie Inc
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : AL002
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : AbbVie Inc
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : AL002 is a Antibody drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Alzheimer Disease.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
October 19, 2020
Lead Product(s) : AL002
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : AbbVie Inc
Deal Size : Inapplicable
Deal Type : Inapplicable

Lead Product(s) : AL002
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Sanders-Brown Study Leads to Potential for a New Treatment Approach to Alzheimer’s Disease
Details : 5XFAD mice in the intracranial administration study were assigned to one of two injection groups: AL002a, a Trem2-agonizing antibody, or MOPC, an isotype-matched control antibody.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
August 25, 2020
Lead Product(s) : AL002
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

Alector Announces Publication of Preclinical and Phase 1 Data Validating Potential of AL002
Details : AL002 was shown to be well-tolerated in a first-in-human Phase 1 SAD study in healthy volunteers and modulated cerebrospinal fluid biomarkers indicative of brain target engagement.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
June 25, 2020

A Phase I Study for Safety and Tolerability of AL002.
Details : AL002 is a Antibody drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Alzheimer Disease.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
August 17, 2018
