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    [{"orgOrder":0,"company":"Akamis Bio","sponsor":"Bristol Myers Squibb","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2021","type":"Collaboration","leadProduct":"NG-641","moa":"||C-X-C motif chemokine 10 (CXCL10)","graph1":"Oncology","graph2":"IND Enabling","graph3":"Akamis Bio","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Akamis Bio \/ Akamis Bio","highestDevelopmentStatusID":"5","companyTruncated":"Akamis Bio \/ Akamis Bio"},{"orgOrder":0,"company":"Akamis Bio","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"UNITED KINGDOM","productType":"Cell and Gene therapy","year":"2020","type":"Inapplicable","leadProduct":"NG-641","moa":"C-X-C motif chemokine 10 (CXCL10)","graph1":"Oncology","graph2":"Phase I","graph3":"Akamis Bio","amount2":0,"highestDevelopmentShortName":"Ph 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Bio","amount2":0.029999999999999999,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0.029999999999999999,"dosageForm":"Infusion","sponsorNew":"Akamis Bio \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"Akamis Bio \/ Undisclosed"},{"orgOrder":0,"company":"Akamis Bio","sponsor":"Bluebird Bio","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"UNITED KINGDOM","productType":"Undisclosed","year":"2021","type":"Inapplicable","leadProduct":"NG-347","moa":"||Undisclosed","graph1":"Oncology","graph2":"IND Enabling","graph3":"Akamis Bio","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Akamis Bio \/ Bluebird Bio","highestDevelopmentStatusID":"5","companyTruncated":"Akamis Bio \/ Bluebird Bio"},{"orgOrder":0,"company":"Akamis Bio","sponsor":"Bristol Myers Squibb","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"UNITED KINGDOM","productType":"Cell and Gene therapy","year":"2021","type":"Inapplicable","leadProduct":"NG-641","moa":"C-X-C motif chemokine 10 (CXCL10)","graph1":"Oncology","graph2":"Phase I","graph3":"Akamis Bio","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Akamis Bio \/ Bristol Myers Squibb","highestDevelopmentStatusID":"6","companyTruncated":"Akamis Bio \/ Bristol Myers Squibb"}]

    Find Clinical Drug Pipeline Developments & Deals by Akamis Bio

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                            01

                            Akamis Bio

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                            Akamis Bio

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                            Lead Product(s) : NG-350A,Capecitabine

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Akamis Begins Phase 1b FORTRESS Trial for Rectal Cancer Therapy

                            Details : NG-350A is a CD40 agonist gene therapy candidate, which is currenty being evaluated for the treatment of locally advanced rectal cancer.

                            Product Name : Undisclosed

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            April 03, 2025

                            Lead Product(s) : NG-350A,Capecitabine

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Akamis Bio

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                            Akamis Bio

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                            Lead Product(s) : NG-350A

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            NG-350A Plus Chemoradiotherapy for Locally Advanced Rectal Cancer

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            June 14, 2024

                            Lead Product(s) : NG-350A

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Akamis Bio

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                            Lead Product(s) : NG-350A

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : $30.0 million

                            Deal Type : Financing

                            DEALS_DEV arrow-down

                            Akamis Bio Announces $30 Million Financing, Provides Clinical Program Update and Relaunches with Name Change f...

                            Details : The net proceeds will fund development activities for the clinical stage NG-350A and NG-641 programs, as well as general corporate purposes. NG-350A is oncolytic adenoviral vector which expresses a full length agonist anti-CD40 antibody at the site of vi...

                            Product Name : Undisclosed

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            June 01, 2023

                            Lead Product(s) : NG-350A

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : $30.0 million

                            Deal Type : Financing

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                            04

                            Akamis Bio

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                            Lead Product(s) : NG-350A

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Merck & Co

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Study of NG-350A Plus Pembrolizumab in Metastatic or Advanced Epithelial Tumours (FORTIFY)

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            December 21, 2021

                            Lead Product(s) : NG-350A

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Merck & Co

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Akamis Bio

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                            Lead Product(s) : NG-641

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Bristol Myers Squibb

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Study of NG-641 in Combination With Nivolumab in Metastatic or Advanced Epithelial Tumours

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            September 14, 2021

                            Lead Product(s) : NG-641

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Bristol Myers Squibb

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Akamis Bio

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                            Lead Product(s) : NG-641,Nivolumab

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Recipient : Bristol Myers Squibb

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            PsiOxus Therapeutics Updates Agreement with Bristol Myers Squibb to Advance their Clinical Stage Immuno-Oncolo...

                            Details : The first stage of this collaboration combined Bristol Myers Squibb’s Opdivo with PsiOxus’ enadenotucirev in the Phase 1 SPICE study to determine the safety and tolerability of combining these two agents, and to optimise the combination intravenous d...

                            Product Name : Undisclosed

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            July 04, 2021

                            Lead Product(s) : NG-641,Nivolumab

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Recipient : Bristol Myers Squibb

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            07

                            Akamis Bio

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                            Lead Product(s) : Undisclosed,NG-347,NG-641

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Bluebird Bio

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            PsiOxus and Bluebird Bio Present Novel Data Combining PsiOxus T-SIGn Platform with CAR-T Therapy to Clear Prim...

                            Details : The study showed that when injected intravenously into mice with established human tumor xenografts, PsiOxus’ armed T-SIGn vectors reprogrammed the tumor microenvironment to a proinflammatory state.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Inapplicable

                            April 14, 2021

                            Lead Product(s) : Undisclosed,NG-347,NG-641

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Bluebird Bio

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Akamis Bio

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                            Lead Product(s) : NG-641

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Study of NG-641 and Pembrolizumab in Squamous Cell Carcinoma of the Head and Neck

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            April 05, 2021

                            Lead Product(s) : NG-641

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Akamis Bio

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                            Lead Product(s) : NG-641

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            PsiOxus Therapeutics Announces Clinical Trial with Third Cancer Gene Therapy Treatment

                            Details : This is the first time that a tumor-specific virus containing four different therapeutic transgenes has been administered to cancer patients.

                            Product Name : Undisclosed

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            May 03, 2020

                            Lead Product(s) : NG-641

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Akamis Bio

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                            Lead Product(s) : NG-641

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            First in Human Study With NG-641, a Tumour Selective Transgene Expressing Adenoviral Vector

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            August 12, 2019

                            Lead Product(s) : NG-641

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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