Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Ajax Therapeutics Begins Phase 1 Trial of AJ1-11095 for Myelofibrosis
Details : AJ1‑11095 is a first-in-class Type II JAK2 inhibitor, being investigated for the treatment of patients with myelofibrosis.
Product Name : AJ1-11095
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
October 30, 2024
Ajax Therapeutics Raises $95 Million Series C for Type II Jak2 Inhibitor AJ1-11095
Details : The proceeds from financing will support the clinical development of Ajax’s first-in-class Type II JAK2 inhibitor, AJ1‑11095, for treating myelofibrosis and related conditions.
Product Name : AJ1-11095
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
May 13, 2024
Ajax Announces FDA Clearance for AJ1-11095, a Type II JAK2 Inhibitor for Myelofibrosis
Details : AJ1-11095 is a first-in-class type II JAK2 inhibitor, small molecule drug candidate, which is currently being evaluated for the treatment of myelofibrosis.
Product Name : AJ1-11095
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
May 13, 2024
Lead Product(s) : AJ1-10502
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : In both MPN models studied, AJ1-10502 demonstrated dose dependent improvements in efficacy over ruxolitinib on key blood cell parameters, including reticulocytes and hematocrit, associated with MPNs, as well as superior reductions in spleen weights on pa...
Product Name : AJ1-10502
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
November 12, 2022
Lead Product(s) : AJ1-10502
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : AJ1-10502
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Ajax Therapeutics, Inc. is pursuing uniquely selective approaches to develop novel first-in-class therapeutic AJ1-10502, for myeloproliferative neoplasms (MPNs), including Myelofibrosis.
Product Name : AJ1-10502
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
March 11, 2022
Lead Product(s) : AJ1-10502
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Discovery Platform
Sponsor : EcoR1 Capital
Deal Size : $40.0 million
Deal Type : Financing
Details : Proceeds from the financing will support the advancement of Ajax’ lead drug development programs targeting hematologic malignancies. The financing will also support the company’s drug discovery pipeline.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
February 06, 2021
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Discovery Platform
Sponsor : EcoR1 Capital
Deal Size : $40.0 million
Deal Type : Financing