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    [{"orgOrder":0,"company":"Aivita Biomedical","sponsor":"PT AIVITA Biomedika | Kariadi Hospital | Central Army Hospital RSPAD Gatot Soebroto","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Vaccine","year":"2021","type":"Inapplicable","leadProduct":"AV-COVID-19","moa":"SARS-CoV-2 S protein","graph1":"Infections and Infectious Diseases","graph2":"Phase II","graph3":"Aivita Biomedical","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Injection","sponsorNew":"Aivita Biomedical \/ PT AIVITA Biomedika | Kariadi Hospital | Central Army Hospital RSPAD Gatot Soebroto","highestDevelopmentStatusID":"8","companyTruncated":"Aivita Biomedical \/ PT AIVITA Biomedika | Kariadi Hospital | Central Army Hospital RSPAD Gatot Soebroto"},{"orgOrder":0,"company":"Aivita Biomedical","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Infections 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    Find Clinical Drug Pipeline Developments & Deals by Aivita Biomedical

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                            01

                            Aivita Biomedical

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                            Lead Product(s) : AV-GBM-1

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            AV-GBM-1 vs Control as Adjunctive Therapy Following Surgery and RT/TMZ in Newly Diagnosed GBM

                            Details : AV-GBM-1 is a Vaccine drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Glioblastoma.

                            Product Name : Undisclosed

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            October 29, 2021

                            Lead Product(s) : AV-GBM-1

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Aivita Biomedical

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                            Lead Product(s) : AV-COVID-19

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Sponsor : PT AIVITA Biomedika | Kariadi Hospital | Central Army Hospital RSPAD Gatot Soebroto

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Preventive Dendritic Cell Vaccine, AV-COVID-19, in Subjects Not Actively Infected With COVID-19

                            Details : AV-COVID-19 is a Vaccine drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of COVID-19.

                            Product Name : Undisclosed

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            August 16, 2021

                            Lead Product(s) : AV-COVID-19

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Sponsor : PT AIVITA Biomedika | Kariadi Hospital | Central Army Hospital RSPAD Gatot Soebroto

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Aivita Biomedical

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                            Lead Product(s) : AV-GBM-1

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            AIVITA Biomedical's Phase 2 Glioblastoma Trial Shows Improved Progression Free Survival

                            Details : AV-GBM-1 is a novel immunotherapy consisting of autologous dendritic cells loaded with autologous tumor neoantigens derived from self-renewing tumor-initiating cells isolated from tumors after routine surgical debulking.

                            Product Name : Undisclosed

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            June 08, 2021

                            Lead Product(s) : AV-GBM-1

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Aivita Biomedical

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                            AAPS
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                            Aivita Biomedical

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                            Lead Product(s) : AV-COVID-19

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I/ Phase II

                            Sponsor : PT AIVITA Biomedika

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            AIVITA Biomedical Completes Phase 1 Study of Personalized COVID-19 Vaccine Candidate, AV-COVID-19

                            Details : AV-COVID-19 is being manufactured locally by AIVITA. AIVITA is in discussions with regulatory authorities for a Phase 2 study in Indonesia, as well as clinical investigation of AV-COVID-19 in the United States in early 2021.

                            Product Name : Undisclosed

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            February 25, 2021

                            Lead Product(s) : AV-COVID-19

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : PT AIVITA Biomedika

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Aivita Biomedical

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                            AAPS
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                            Aivita Biomedical

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                            Lead Product(s) : AV-COVID-19

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Sponsor : PT AIVITA Biomedika | Indonesia Ministry of Health | NIHRD, Ministry of Health, Indonesia

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Dendritic Cell Vaccine, AV-COVID-19, to Prevent COVID-19 Infection

                            Details : AV-COVID-19 is a Vaccine drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of COVID-19.

                            Product Name : Undisclosed

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            December 30, 2020

                            Lead Product(s) : AV-COVID-19

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Sponsor : PT AIVITA Biomedika | Indonesia Ministry of Health | NIHRD, Ministry of Health, Indonesia

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Aivita Biomedical

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                            AAPS
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                            Aivita Biomedical

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                            Lead Product(s) : AV-GBM-1

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : $25.0 million

                            Deal Type : Series B Financing

                            DEALS_DEV arrow-down

                            AIVITA Biomedical Closes $25 Million Financing Round

                            Details : Proceeds will support clinical development of AIVITA’s personalized immunotherapy programs, including Phase 2 studies in glioblastoma and ovarian cancer, as well as AIVITA’s application for commercial approval of its melanoma immunotherapy.

                            Product Name : Undisclosed

                            Product Type : Vaccine

                            Upfront Cash : Undisclosed

                            December 29, 2020

                            Lead Product(s) : AV-GBM-1

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : $25.0 million

                            Deal Type : Series B Financing

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                            07

                            Aivita Biomedical

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                            AAPS
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                            Aivita Biomedical

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                            Lead Product(s) : AV-GBM-1

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            AIVITA Biomedical's Phase 2 Glioblastoma Trial Shows Improved Progression Free Survival

                            Details : The analysis focused on 57 patients who were scheduled to receive up to eight doses of AV-GBM-1 over approximately six months. At the time of the analysis, surviving patients had completed therapy and had been followed between 7.2 and 24.2 months.

                            Product Name : Undisclosed

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            November 17, 2020

                            Lead Product(s) : AV-GBM-1

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Aivita Biomedical

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                            AAPS
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                            Aivita Biomedical

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                            Lead Product(s) : AV-GBM-1

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            AIVITA Biomedical Completes Treatment of Patients in Phase 2 Clinical Trial of Glioblastoma Immunotherapy

                            Details : The eight-site, single-arm study investigates AV-GBM-1, AIVITA’s novel immunotherapy for the treatment of glioblastoma that targets the autologous tumor-initiating cells responsible for the rapid growth and proliferation of the disease.

                            Product Name : Undisclosed

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            November 02, 2020

                            Lead Product(s) : AV-GBM-1

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Aivita Biomedical

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                            AAPS
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                            Aivita Biomedical

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                            Lead Product(s) : AVOVA-1,GM-CSF

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            AIVITA Biomedical Publishes Review of GM-CSF History and Rationale as Vaccine Adjuvant in Melanoma Management

                            Details : Randomized trials have failed to confirm significant anticancer activity for monotherapy GM-CSF, but it appears to provide immune enhancing effects and survival benefit when it is admixed with dendritic cells loaded ex-vivo with autologous tumor antigens

                            Product Name : Undisclosed

                            Product Type : Cell & Gene Therapy

                            Upfront Cash : Inapplicable

                            August 03, 2020

                            Lead Product(s) : AVOVA-1,GM-CSF

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Aivita Biomedical

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                            AAPS
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                            Aivita Biomedical

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                            Lead Product(s) : AV-COVID-19

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Phase I-II Trial of Dendritic Cell Vaccine to Prevent COVID-19 in Adults

                            Details : AV-COVID-19 is a Vaccine drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of COVID-19.

                            Product Name : Undisclosed

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            May 13, 2020

                            Lead Product(s) : AV-COVID-19

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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