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    [{"orgOrder":0,"company":"Aisa Pharma","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"AISA Pharma Announces Positive Data Safety Monitoring Board Review of First Phase 2 Data of Profervia\u00ae to treat Raynaud\u2019s Disease in Scleroderma Patients","therapeuticArea":"Immunology","highestDevelopmentStatus":"Phase II","country":"U.S.A","productType":"Small molecule","productStatus":"Approved","date":"July 2022","url1":"","url2":"","graph1":"Immunology","graph2":"Phase II"},{"orgOrder":0,"company":"Aisa Pharma","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"AISA Pharma Announces NIH-NINDS Award To Investigate Profervia\u00ae as A Non-Opioid Analgesic for Acute and Chronic Pain","therapeuticArea":"Neurology","highestDevelopmentStatus":"Phase II","country":"U.S.A","productType":"Small molecule","productStatus":"Approved","date":"April 2023","url1":"","url2":"","graph1":"Neurology","graph2":"Phase II"},{"orgOrder":0,"company":"Aisa Pharma","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"AISA Pharma Announces Start of Phase 2b Profervia Study for Raynaud's Phenomenon in Systemic Sclerosis (SSc)","therapeuticArea":"Immunology","highestDevelopmentStatus":"Phase II","country":"U.S.A","productType":"Small molecule","productStatus":"Approved","date":"June 2023","url1":"","url2":"","graph1":"Immunology","graph2":"Phase II"}]

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              AISA Pharma Announces Start of Phase 2b Profervia Study for Raynaud's Phenomenon in Systemic Sclerosis (SSc)

              Details:

              Profervia is a novel form of cilnidipine, a fourth-generation calcium channel blocker (CCB), which is investigated for the treatment of Raynaud's Phenomenon in Systemic Sclerosis (SSc).

              Lead Product(s): Cilnidipine,Tadalafil

              Therapeutic Area: Immunology Product Name: Profervia

              Highest Development Status: Phase II Product Type: Small molecule

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable June 21, 2023

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              AISA Pharma Announces NIH-NINDS Award To Investigate Profervia® as A Non-Opioid Analgesic for Acute and Chronic Pain

              Details:

              Profervia® is a novel form of cilnidipine, a fourth-generation calcium channel blocker(CCB). Cilnidipine is approved in select Asian countries for hypertension with decades of safety data.

              Lead Product(s): Cilnidipine

              Therapeutic Area: Neurology Product Name: Profervia

              Highest Development Status: Phase II Product Type: Small molecule

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable April 03, 2023

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              AISA Pharma Announces Positive Data Safety Monitoring Board Review of First Phase 2 Data of Profervia® to treat Raynaud’s Disease in Scleroderma Patients

              Details:

              Profervia® is a reformulated form of Cilnidipine, a novel calcium channel blocker (CCB) only approved in several Asian countries for treating hypertension, but never approved anywhere in the World for the treatment of Scleroderma and Raynaud’s.

              Lead Product(s): Cilnidipine

              Therapeutic Area: Immunology Product Name: Profervia

              Highest Development Status: Phase II Product Type: Small molecule

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable July 26, 2022

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              Inke S.A: APIs manufacturing plant.
              ChemWerth works in generic API development & supply, non-infringement patent strategy development and regulatory support.
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