Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Zelpultide Alpha
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Airway Therapeutics Starts Phase 3 Zelpultide Alfa Trial for Neonates
Details : AT-100 (zelpultide alfa) is a recombinant version of human surfactant protein D (rhSP-D), being developed foe the treatment of bronchopulmonary dysplasia.
Product Name : AT-100
Product Type : Protein
Upfront Cash : Inapplicable
October 15, 2024
Lead Product(s) : Zelpultide Alpha
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Zelpultide Alpha
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : AT-100 (zelpultide alfa) is a recombinant version of the endogenous human SP-D, a protein essential to the lung’s immune defense in reducing inflammation and infection while modulating immune response. It is being investigated in preterm infants for br...
Product Name : AT-100
Product Type : Protein
Upfront Cash : Inapplicable
November 04, 2023
Lead Product(s) : Zelpultide Alpha
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Zelpultide Alpha
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : AT-100 (zelpultide alfa) is a recombinant version of the endogenous human SP-D, a protein essential to the lung’s immune defense in reducing inflammation and infection while modulating immune responses for the patients of Bronchopulmonary Dysplasia.
Product Name : AT-100
Product Type : Protein
Upfront Cash : Inapplicable
May 06, 2023
Lead Product(s) : Zelpultide Alpha
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Zelpultide Alpha
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : In preclinical studies, AT-100 has shown to reduce inflammation and infection triggered by mechanical ventilation and oxygen support, and ultimately reduce the onset of lung damage.
Product Name : AT-100
Product Type : Protein
Upfront Cash : Inapplicable
March 31, 2022
Lead Product(s) : Zelpultide Alpha
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Zelpultide Alpha
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Zelpultide alfa (AT-100) is a novel recombinant version of the endogenous human protein hSP-D, a protein that reduces inflammation and infection in the body while modulating the immune response to break the cycle of injury and inflammation.
Product Name : AT-100
Product Type : Protein
Upfront Cash : Inapplicable
March 10, 2022
Lead Product(s) : Zelpultide Alpha
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Zelpultide Alpha
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Preclinical studies have shown that the human recombinant protein ,AT-100, can safely minimise inflammation and infection while modulating the immune response in a variety of respiratory diseases both inside and outside the lung.
Product Name : AT-100
Product Type : Protein
Upfront Cash : Inapplicable
December 04, 2021
Lead Product(s) : Zelpultide Alpha
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Zelpultide Alpha
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : AT-100 is a novel human recombinant protein that has been shown in preclinical studies to reduce inflammation and infection triggered in very preterm babies by mechanical ventilation and oxygen support and ultimately reduce the onset of lung damage.
Product Name : AT-100
Product Type : Protein
Upfront Cash : Inapplicable
March 26, 2021
Lead Product(s) : Zelpultide Alpha
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Zelpultide Alpha
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Airway Therapeutics Announces Filing with NIH to Evaluate AT-100 as a Therapy for Novel Coronavirus
Details : Airway is aiming to enter the clinic later this year with AT-100 as an investigational preventive treatment for the serious respiratory disease.
Product Name : AT-100
Product Type : Protein
Upfront Cash : Inapplicable
November 03, 2020
Lead Product(s) : Zelpultide Alpha
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Zelpultide Alpha
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Preclinical
Sponsor : Undisclosed
Deal Size : $15.5 million
Deal Type : Series C Financing
Details : This funding will enable clinical development of AT-100 (rhSP-D), while also supporting preclinical research in influenza, respiratory syncytial virus (RSV) and cystic fibrosis.
Product Name : AT-100
Product Type : Protein
Upfront Cash : Undisclosed
August 01, 2020
Lead Product(s) : Zelpultide Alpha
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Preclinical
Sponsor : Undisclosed
Deal Size : $15.5 million
Deal Type : Series C Financing