

Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass.
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Lead Product(s) : Sintilimab,Afuresertib,Paclitaxel
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Laekna Therapeutics
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The combination therapy consists of Laekna’s afuresertib (LAE002), a highly selective ATP competitive AKT inhibitor in clinical trials with favorable efficacy and safety profile, and Innovent’s PD-1 inhibitor sintilimab (TYVYT), which has been approv...
Product Name : Tyvyt
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
August 01, 2022
Lead Product(s) : Sintilimab,Afuresertib,Paclitaxel
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Laekna Therapeutics
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Afuresertib
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Afuresertib is a Other Small Molecule drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Neoplasms.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
May 20, 2022
Lead Product(s) : Afuresertib
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Afuresertib,Sintilimab,Undisclosed
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Innovent Biologics
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : LAE002 (Afuresertib) a potent next-generation small molecule pan-AKT kinase inhibitor in combination with sintilimab and chemotherapy, targets patients with specific solid tumors who have been refractory to treatment with PD-1/PD-L1 inhibitors.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
January 09, 2022
Lead Product(s) : Afuresertib,Sintilimab,Undisclosed
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Innovent Biologics
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Afuresertib,Fulvestrant
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Afuresertib is a clinically proven, highly potent small-molecule pan-AKT inhibitor. Afuresertib is being studied in global clinical studies in four different cancers including ovarian cancer, prostate cancer, triple-negative breast cancer, and HR+/HER2- ...
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
August 26, 2021
Lead Product(s) : Afuresertib,Fulvestrant
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Sintilimab,Afuresertib
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Laekna Therapeutics
Deal Size : Undisclosed
Deal Type : Partnership
Details : The companies will work together to conduct clinical studies assessing the combination of sintilimab and afuresertib (LAE002) in patients with multiple types of solid tumors that have been refractory-or failed to respond-to treatment with PD-1/PD-L1 inhi...
Product Name : Tyvyt
Product Type : Antibody, Unconjugated
Upfront Cash : Undisclosed
July 05, 2021
Lead Product(s) : Sintilimab,Afuresertib
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Laekna Therapeutics
Deal Size : Undisclosed
Deal Type : Partnership

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Lead Product(s) : Afuresertib
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Afuresertib is a Other Small Molecule drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Breast Neoplasms.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
April 20, 2021
Lead Product(s) : Afuresertib
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

Lead Product(s) : LAE005,Afuresertib
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Laekna Therapeutics
Deal Size : Undisclosed
Deal Type : Agreement
Details : According to the agreement, CMAB will provide a full spectrum of CMC services based on the recognized global quality standards for Laekna Therapeutics’ anti-PD-L1 antibody (LAE005).
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Undisclosed
September 09, 2020
Lead Product(s) : LAE005,Afuresertib
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Laekna Therapeutics
Deal Size : Undisclosed
Deal Type : Agreement

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Lead Product(s) : Afuresertib
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Afuresertib is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Neoplasms.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
March 05, 2015
Lead Product(s) : Afuresertib
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Afuresertib
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Study of Afuresertib Combined With Paclitaxel in Gastric Cancer
Details : Afuresertib is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Neoplasms.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
September 15, 2014
Lead Product(s) : Afuresertib
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Afuresertib
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Amgen Inc
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Afuresertib is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Neoplasms.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
September 10, 2014
Lead Product(s) : Afuresertib
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Amgen Inc
Deal Size : Inapplicable
Deal Type : Inapplicable
