Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : 3-beta-(4-methoxybenzyloxy)pregn-5-en-20-one
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : National Institute on Drug Abuse
Deal Size : Inapplicable
Deal Type : Inapplicable
Drug-Drug Interaction Between THC and AEF0117
Details : Undisclosed
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
May 02, 2024
Lead Product(s) : 3-beta-(4-methoxybenzyloxy)pregn-5-en-20-one
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : National Institute on Drug Abuse
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : AEF0117
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Indivior
Deal Size : Inapplicable
Deal Type : Inapplicable
Indivior Updates Aelis Farma's Phase 2B Results for Cannabis Use Disorder
Details : AEF0117 is an oral drug candidate, being evaluated for its efficacy and safety in treatment-seeking participants with moderate to severe Cannabis Use Disorder (CUD).
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
April 09, 2024
Lead Product(s) : AEF0117
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Indivior
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : AEF0217
Therapeutic Area : Neurology
Study Phase : Phase I/ Phase II
Sponsor : European Commission
Deal Size : Inapplicable
Deal Type : Inapplicable
Phase 1/2 Trial of AEF0217 in Participants With Down Syndrome
Details : Undisclosed
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
February 28, 2023
Lead Product(s) : AEF0217
Therapeutic Area : Neurology
Highest Development Status : Phase I/ Phase II
Sponsor : European Commission
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : AEF0117
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Study of [4-14C] AEF0117 Following a Single Oral Dose in Healthy Male Subjects
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
September 26, 2022
Lead Product(s) : AEF0117
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : 3-beta-(4-methoxybenzyloxy)pregn-5-en-20-one
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : National Institute on Drug Abuse
Deal Size : Inapplicable
Deal Type : Inapplicable
The Effect of Food on the Oral Bioavailability of AEF0117 in Healthy Volunteers
Details : Undisclosed
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
July 11, 2022
Lead Product(s) : 3-beta-(4-methoxybenzyloxy)pregn-5-en-20-one
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : National Institute on Drug Abuse
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : AEF0117
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Effect of AEF0117 on Treatment-seeking Patients With Cannabis Use Disorder (CUD)
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
April 12, 2022
Lead Product(s) : AEF0117
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : AEF0117
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Recipient : Indivior
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Following the promising results of a Phase 2a study showing that AEF0117 reduced the subjective effects of cannabis and cannabis self-administration in subjects with moderate to severe CUD.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
January 06, 2022
Lead Product(s) : AEF0117
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Recipient : Indivior
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : AEF0217
Therapeutic Area : Undisclosed
Study Phase : Phase I
Sponsor : European Commission
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Undisclosed
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
December 28, 2021
Lead Product(s) : AEF0217
Therapeutic Area : Undisclosed
Highest Development Status : Phase I
Sponsor : European Commission
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : AEF0117
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Indivior
Deal Size : $130.0 million
Deal Type : Collaboration
Details : Indivior has entered into a strategic collaboration with Aelis Farma ("Aelis"), a private biotechnology company based in Bordeaux, France, that includes an exclusive option and license agreement (the "Agreement") for the global rights to AEF0117.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : $30.0 million
August 06, 2021
Lead Product(s) : AEF0117
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Indivior
Deal Size : $130.0 million
Deal Type : Collaboration
Lead Product(s) : AEF0117
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : National Institute on Drug Abuse | Columbia University | New York State Psychiatric Institute | ClinStar
Deal Size : Inapplicable
Deal Type : Inapplicable
Effect of AEF0117 on Subjective Effects of Cannabis in CUD Subjects
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
October 24, 2018
Lead Product(s) : AEF0117
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : National Institute on Drug Abuse | Columbia University | New York State Psychiatric Institute | ClinStar
Deal Size : Inapplicable
Deal Type : Inapplicable