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    [{"orgOrder":0,"company":"Acumen Pharmaceuticals","sponsor":"BofA Securities","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Antibody","year":"2023","type":"Public Offering","leadProduct":"Sabirnetug","moa":"Amyloid-beta","graph1":"Neurology","graph2":"Phase II\/ Phase III","graph3":"Acumen Pharmaceuticals","amount2":0.10000000000000001,"highestDevelopmentShortName":"Ph II\/III","therapeuticAreaShortName":"Neurology","amount2New":0.16,"dosageForm":"Intravenous Infusion","sponsorNew":"Acumen Pharmaceuticals \/ BofA Securities","highestDevelopmentStatusID":"9","companyTruncated":"Acumen Pharmaceuticals \/ BofA Securities"},{"orgOrder":0,"company":"Acumen Pharmaceuticals","sponsor":"BofA Securities","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Antibody","year":"2023","type":"Public Offering","leadProduct":"Sabirnetug","moa":"Amyloid-beta","graph1":"Neurology","graph2":"Phase II\/ Phase 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    Find Clinical Drug Pipeline Developments & Deals by Acumen Pharmaceuticals

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                            01

                            Acumen Pharmaceuticals

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                            Acumen Pharmaceuticals

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Neurology

                            Study Phase : Preclinical

                            Recipient : JCR Pharmaceuticals

                            Deal Size : $515.0 million

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Acumen Taps JCR’s Blood-Brain Barrier Tech for $555M Alzheimer’s Deal

                            Details : Acumen and JCR will co-develop a preclinical oligomer-targeted EBD therapy for Alzheimer’s, enhancing Acumen’s antibodies with JCR’s J‑Brain Cargo BBB delivery platform.

                            Product Name : Undisclosed

                            Product Type : Antibody

                            Upfront Cash : Undisclosed

                            July 15, 2025

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Neurology

                            Highest Development Status : Preclinical

                            Recipient : JCR Pharmaceuticals

                            Deal Size : $515.0 million

                            Deal Type : Collaboration

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                            02

                            Acumen Pharmaceuticals

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                            AGGSpend
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                            Lead Product(s) : Sabirnetug

                            Therapeutic Area : Neurology

                            Study Phase : Phase II/ Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Acumen Completes ALTITUDE-AD Phase 2 Enrollment for Sabirnetug in Alzheimer’s

                            Details : ACU193 (sabirnetug) is a humanized monoclonal antibody (mAb), it selectively targets toxic soluble AβOs which is the primary underlying cause of the neurodegenerative process in alzheimer’s disease.

                            Product Name : ACU193

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            March 26, 2025

                            Lead Product(s) : Sabirnetug

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Acumen Pharmaceuticals

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                            AGGSpend
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                            Acumen Pharmaceuticals

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                            Lead Product(s) : Sabirnetug,Hyaluronidase Enzyme

                            Therapeutic Area : Neurology

                            Study Phase : Phase II/ Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Acumen Reports Phase 1 Data for Subcutaneous Sabirnetug in Healthy Volunteers

                            Details : ACU193 (sabirnetug) is a humanized monoclonal antibody (mAb), it selectively targets toxic soluble AβOs which is the primary underlying cause of the neurodegenerative process in alzheimer’s disease.

                            Product Name : ACU193

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            March 19, 2025

                            Lead Product(s) : Sabirnetug,Hyaluronidase Enzyme

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Acumen Pharmaceuticals

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                            AGGSpend
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                            Acumen Pharmaceuticals

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                            Lead Product(s) : Sabirnetug

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Lonza Group

                            Deal Size : Undisclosed

                            Deal Type : Expanded Collaboration

                            DEALS_DEV arrow-down

                            Acumen Pharmaceuticals Extends Alzheimer’s Collaboration with Lonza

                            Details : The collaboration aims to enable the potential future commercial launch of ACU193 (sabirnetug), the first humanized mAb to clinically demonstrate selective target engagement of amyloid beta oligomers.

                            Product Name : ACU193

                            Product Type : Antibody

                            Upfront Cash : Undisclosed

                            September 27, 2024

                            Lead Product(s) : Sabirnetug

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Lonza Group

                            Deal Size : Undisclosed

                            Deal Type : Expanded Collaboration

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                            05

                            Acumen Pharmaceuticals

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                            AGGSpend
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                            Acumen Pharmaceuticals

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                            Lead Product(s) : Sabirnetug

                            Therapeutic Area : Neurology

                            Study Phase : Phase II/ Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Acumen Doses First Patient In Phase 2 Of Sabirnetug In Early Alzheimer's Disease

                            Details : ACU193 (sabirnetug) is a humanized monoclonal antibody (mAb), it selectively targets toxic soluble AβOs which is the primary underlying cause of the neurodegenerative process in alzheimer’s disease.

                            Product Name : ACU193

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            August 05, 2024

                            Lead Product(s) : Sabirnetug

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Acumen Pharmaceuticals

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                            AGGSpend
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                            Acumen Pharmaceuticals

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                            Lead Product(s) : Sabirnetug

                            Therapeutic Area : Neurology

                            Study Phase : Phase II/ Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Acumen Doses First Patient in ALTITUDE-AD Phase 2 Trial for Early Alzheimer’s

                            Details : ACU193 (sabirnetug) is a humanized monoclonal antibody that targets toxic soluble amyloid beta oligomers. It is being evaluated for the treatment of early alzheimer’s disease.

                            Product Name : ACU193

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            August 05, 2024

                            Lead Product(s) : Sabirnetug

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Acumen Pharmaceuticals

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                            AGGSpend
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                            Acumen Pharmaceuticals

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                            Lead Product(s) : Sabirnetug

                            Therapeutic Area : Neurology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Acumen Pharmaceuticals Doses First Subject in Phase 1 Study of Sabirnetug for Alzheimer’s

                            Details : ACU193 (sabirnetug) is a humanized monoclonal antibody (mAb), it selectively targets toxic soluble AβOs which is the primary underlying cause of the neurodegenerative process in alzheimer’s disease.

                            Product Name : ACU193

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            July 29, 2024

                            Lead Product(s) : Sabirnetug

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Acumen Pharmaceuticals

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                            AGGSpend
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                            Acumen Pharmaceuticals

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                            AGGSpend
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                            Lead Product(s) : Sabirnetug

                            Therapeutic Area : Neurology

                            Study Phase : Phase I

                            Sponsor : K2 HealthVentures

                            Deal Size : Undisclosed

                            Deal Type : Financing

                            DEALS_DEV arrow-down

                            Acumen Pharmaceuticals Secures $50.0 Million Credit Facility with K2 HealthVentures

                            Details : The proceends will be used to support development of a subcutaneous formulation of ACU193, a humanized monoclonal antibody that selectively targets toxic soluble amyloid beta oligomers.

                            Product Name : ACU193

                            Product Type : Antibody

                            Upfront Cash : Undisclosed

                            November 13, 2023

                            Lead Product(s) : Sabirnetug

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase I

                            Sponsor : K2 HealthVentures

                            Deal Size : Undisclosed

                            Deal Type : Financing

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                            09

                            Acumen Pharmaceuticals

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                            AGGSpend
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                            Acumen Pharmaceuticals

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                            Lead Product(s) : Sabirnetug

                            Therapeutic Area : Neurology

                            Study Phase : Phase I

                            Sponsor : BofA Securities

                            Deal Size : $130.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Acumen Announces Pricing of Upsized $130 Million Public Offering

                            Details : Acumen intends to use its net proceeds to fund the Phase 2 portion of a future, potential Phase 2/3 adaptable trial of ACU193, an anti-AβO mAb developed to selectively target and inhibit toxic soluble AβOs, to fund chemistry, manufacturing and other R&...

                            Product Name : ACU193

                            Product Type : Antibody

                            Upfront Cash : Undisclosed

                            July 18, 2023

                            Lead Product(s) : Sabirnetug

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase I

                            Sponsor : BofA Securities

                            Deal Size : $130.0 million

                            Deal Type : Public Offering

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                            10

                            Acumen Pharmaceuticals

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                            AGGSpend
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                            Acumen Pharmaceuticals

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                            Lead Product(s) : Sabirnetug

                            Therapeutic Area : Neurology

                            Study Phase : Phase I

                            Sponsor : BofA Securities

                            Deal Size : $100.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Acumen Pharmaceuticals Announces Proposed Public Offering of Common Stock

                            Details : Acumen intends to use its net proceeds to fund the Phase 2 portion of a future, potential Phase 2/3 adaptable trial of ACU193, an anti-AβO mAb developed to selectively target and inhibit toxic soluble AβOs, to fund chemistry, manufacturing and other R&...

                            Product Name : ACU193

                            Product Type : Antibody

                            Upfront Cash : Undisclosed

                            July 17, 2023

                            Lead Product(s) : Sabirnetug

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase I

                            Sponsor : BofA Securities

                            Deal Size : $100.0 million

                            Deal Type : Public Offering

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