
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

Details : ABS-1230 is a Small Molecule drug candidate drug candidate, which is currently being evaluated in Phase I clinical studies for the treatment of Epilepsy.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
September 05, 2025

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Lead Product(s) : ABS-1230
Therapeutic Area : Neurology
Study Phase : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
FDA Clears IND, Fast Track For Actio’s ABS-1230 In KCNT1 Epilepsy
Details : ABS-1230 is an expected first-in-class, orally administered small molecule KCNT1 inhibitor, for the treatment of KCNT1-related epilepsy.
Product Name : ABS-1230
Product Type : Miscellaneous
Upfront Cash : Inapplicable
July 30, 2025
Lead Product(s) : ABS-1230
Therapeutic Area : Neurology
Highest Development Status : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : ABS-1230
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : Regeneron Ventures
Deal Size : $66.0 million
Deal Type : Series B Financing
Actio Biosciences Raises $66M Series B for Small Molecules in Rare Diseases
Details : The financing aims to advance the Actio’s pipeline, which is led by ABS-1230, a KCNT1 inhibitor for the treatment of KCNT1-related epilepsy and other genetic epilepsies.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
June 18, 2025
Lead Product(s) : ABS-1230
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : Regeneron Ventures
Deal Size : $66.0 million
Deal Type : Series B Financing

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Lead Product(s) : ABS-0871
Therapeutic Area : Genetic Disease
Study Phase : Phase I
Sponsor : Saniona
Deal Size : Inapplicable
Deal Type : Inapplicable
Actio Biosciences Doses First Participant in ABS-0871 Phase 1 Trial
Details : ABS-0871 is a TRPV4 antagonist. small molecule drug candidate, which is currently being evaluated for the treatment of charcot marie tooth disease 2C.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
March 03, 2025
Lead Product(s) : ABS-0871
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I
Sponsor : Saniona
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Undisclosed
Therapeutic Area : Genetic Disease
Study Phase : Preclinical
Sponsor : Canaan Partners
Deal Size : $55.0 million
Deal Type : Series A Financing
Details : The proceeds will advance precision medicine approach for rare and common diseases and its lead small molecule program targeting TRPV4 mutations advancing toward clinic for treatment of Charcot-Marie-Tooth disease type 2C and other serious bone diseases.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
September 12, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Genetic Disease
Highest Development Status : Preclinical
Sponsor : Canaan Partners
Deal Size : $55.0 million
Deal Type : Series A Financing
