[{"orgOrder":0,"company":"Lotus Pharmaceutical","sponsor":"Klinge Pharma","pharmaFlowCategory":"D","therapeuticArea":"Ophthalmology","country":"GERMANY","productType":"Protein","year":"2025","type":"Licensing Agreement","leadProduct":"Aflibercept","moa":"Vascular endothelial growth factor A | Placenta growth factor","graph1":"Ophthalmology","graph2":"Approved FDF","graph3":"Lotus Pharmaceutical","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Intravitreal Injection","sponsorNew":"Lotus Pharmaceutical \/ Lotus Pharmaceutical","highestDevelopmentStatusID":"15","companyTruncated":"Lotus Pharmaceutical \/ Lotus Pharmaceutical"},{"orgOrder":0,"company":"Lotus Pharmaceutical","sponsor":"LENZ Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Other Small Molecule","year":"2025","type":"Licensing Agreement","leadProduct":"Aceclidine Hydrochloride","moa":"||Undisclosed","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Lotus Pharmaceutical","amount2":0.13,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0.13,"dosageForm":"Ophthalmic Solution","sponsorNew":"Lotus Pharmaceutical \/ Lotus Pharmaceutical","highestDevelopmentStatusID":"10","companyTruncated":"Lotus Pharmaceutical \/ Lotus Pharmaceutical"},{"orgOrder":0,"company":"Lotus Pharmaceutical","sponsor":"Corium","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Other Small Molecule","year":"2023","type":"Licensing Agreement","leadProduct":"Donepezil","moa":"Acetylcholinesterase","graph1":"Neurology","graph2":"Approved FDF","graph3":"Lotus Pharmaceutical","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Transdermal Patch","sponsorNew":"Lotus Pharmaceutical \/ Lotus Pharmaceutical","highestDevelopmentStatusID":"15","companyTruncated":"Lotus Pharmaceutical \/ Lotus Pharmaceutical"}]

Find Clinical Drug Pipeline Developments & Deals by Actavis Inc

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Peptide Process CMC
                          Not Confirmed
                          Peptide Process CMC
                          Not Confirmed

                          Details : Under the licensing agreement, Lotus will holds the rights of LNZ100 (Aceclidine HCl) in Korea, which is being evaluated for the treatment of Presbyopia.

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          May 09, 2025

                          Lead Product(s) : Aceclidine Hydrochloride,Brimonidine Tartrate

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase III

                          Recipient : LENZ Therapeutics

                          Deal Size : $125.0 million

                          Deal Type : Licensing Agreement

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                          02

                          Peptide Process CMC
                          Not Confirmed
                          Peptide Process CMC
                          Not Confirmed

                          Details : Through the collaboration, Lotus will lead the commercialization of Ahzantive (Aflibercept) in the designated regions, a biosimilar candidate to Eylea.

                          Product Name : Ahzantive

                          Product Type : Protein

                          Upfront Cash : Undisclosed

                          February 05, 2025

                          Lead Product(s) : Aflibercept

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Approved FDF

                          Recipient : Klinge Pharma

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          03

                          Peptide Process CMC
                          Not Confirmed
                          Peptide Process CMC
                          Not Confirmed

                          Details : Under the terms of the agreement, Lotus will have exclusive rights to commercialize Adlarity (donepezil transdermal system), an innovative Alzheimer’s dementia treatment, in the applicable territory and will be responsible for the regulatory approval p...

                          Product Name : Adlarity

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          October 08, 2023

                          Lead Product(s) : Donepezil

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved FDF

                          Recipient : Corium

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          04

                          Peptide Process CMC
                          Not Confirmed
                          Peptide Process CMC
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Controlled Substance

                          Upfront Cash : Inapplicable

                          May 21, 2019

                          Lead Product(s) : Cebranopadol

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Phase I

                          Recipient : Tris Pharma Inc

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          Peptide Process CMC
                          Not Confirmed
                          Peptide Process CMC
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          May 17, 2019

                          Lead Product(s) : Oxymetazoline Hydrochloride

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase III

                          Sponsor : Teva Pharmaceutical Industries

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          Peptide Process CMC
                          Not Confirmed
                          Peptide Process CMC
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Controlled Substance

                          Upfront Cash : Inapplicable

                          March 20, 2019

                          Lead Product(s) : Cebranopadol

                          Therapeutic Area : Undisclosed

                          Highest Development Status : Phase I

                          Recipient : Tris Pharma Inc

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          Peptide Process CMC
                          Not Confirmed

                          08

                          Peptide Process CMC
                          Not Confirmed
                          Peptide Process CMC
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          April 17, 2018

                          Lead Product(s) : Nepafenac

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          Peptide Process CMC
                          Not Confirmed
                          Peptide Process CMC
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          October 04, 2017

                          Lead Product(s) : Ivermectin

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase III

                          Sponsor : Teva Pharmaceutical Industries

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          Peptide Process CMC
                          Not Confirmed