
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : KL1333
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase II
Sponsor : Pharming
Deal Size : $66.1 million
Deal Type : Acquisition
Pharming Pays $66M to for Abliva, Mitochondrial Disease Med
Details : The proposed acquisition will strengthen Pharming’s late-stage pipeline disease asset. Abliva’s lead product, KL1333, is being evaluated for mitochondrial diseases.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
December 15, 2024
Lead Product(s) : KL1333
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase II
Sponsor : Pharming
Deal Size : $66.1 million
Deal Type : Acquisition

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Lead Product(s) : KL1333
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Abliva Report Positive Interim Analysis of FALCON Study of KL1333 in Mitochondrial Disease
Details : Abliva lead product candidate KL1333 is being evaluated in the mid-stage clinical trial studies with patients for the treatment of Primary Mitochondrial Disease.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
July 18, 2024
Lead Product(s) : KL1333
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : OWL-1410
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Study Phase : IND Enabling
Sponsor : Owl Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Under the collaboration, Owl Therapeutics will advance Abliva's clinical development of NeuroSTAT (OWL-1410) with orphan drug designation, which is under development for the prevention and treatment of moderate to severe traumatic brain injury (TBI).
Product Name : NeuroSTAT
Product Type : Peptide, Unconjugated
Upfront Cash : Undisclosed
November 17, 2023
Lead Product(s) : OWL-1410
Therapeutic Area : Trauma (Emergency, Injury, Surgery)
Highest Development Status : IND Enabling
Sponsor : Owl Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration

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Lead Product(s) : KL1333
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Efficacy of KL1333 in Adult Patients With Primary Mitochondrial Disease
Details : KL1333 is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Mitochondrial Diseases.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
December 14, 2022
Lead Product(s) : KL1333
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : KL1333
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Drug-drug Interaction Study of KL1333 in Healthy Subjects
Details : KL1333 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Mitochondrial Diseases.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
November 25, 2020
Lead Product(s) : KL1333
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : KL1333
Therapeutic Area : Genetic Disease
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Abliva receives positive FDA feedback on its KL1333 development plant
Details : KL1333 is a potent modulator of the cellular levels of NAD, a central co-enzyme in the cell’s energy metabolism. The clinical KL1333 development plan will target patients with genetically confirmed MIDD-MELAS or KSS-CPEO spectrum disorders with multi-o...
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
July 10, 2020
Lead Product(s) : KL1333
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : KL1333
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : KL1333 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Mitochondrial Diseases.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
March 25, 2019
Lead Product(s) : KL1333
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
