
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : Denatonium Acetate
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
The Hunger Elimination or Reduction Objective (HERO ) Open -Label Extension (OLE) Trial
Details : Denatonium Acetate is a Small Molecule drug candidate drug candidate, which is currently being evaluated in Phase III clinical studies for the treatment of Hyperphagia.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
September 29, 2025
Lead Product(s) : Denatonium Acetate
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : ARD-201
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Aardvark’s ARD-201 Shows Strong Preclinical Weight Loss, GLP-1RA Synergy
Details : ARD-201 is a DPP-4 inhibitor small molecule drug candidate, which is currently being evaluated for the treatment of obesity.
Product Name : ARD-201
Product Type : Miscellaneous
Upfront Cash : Inapplicable
August 12, 2025
Lead Product(s) : ARD-201
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Denatonium Acetate
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
ARD-101 for Treatment of PWS: The Hunger Elimination or Reduction Objective Trial
Details : ARD-101 is a Other Small Molecule drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Hyperphagia.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
February 17, 2025
Lead Product(s) : Denatonium Acetate
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Denatonium Acetate
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Phase III
Sponsor : Morgan Stanley
Deal Size : $94.2 million
Deal Type : Public Offering
Aardvark Therapeutics Announces Pricing of Initial Public Offering
Details : The proceeds from the offering will be used to advance company's lead candidate molecule, ARD-101, as well as its secondary molecule ARD-201, both of which treat hyperphagia.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
February 13, 2025
Lead Product(s) : Denatonium Acetate
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Phase III
Sponsor : Morgan Stanley
Deal Size : $94.2 million
Deal Type : Public Offering

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Lead Product(s) : Denatonium Acetate
Therapeutic Area : Genetic Disease
Study Phase : Phase II
Sponsor : Cantor Fitzgerald
Deal Size : $85.0 million
Deal Type : Series C Financing
Aardvark Therapeutics Announces $85 Million Oversubscribed Series C Financing
Details : Aardvark intends to use proceeds for trials of ARD-101, a TAS2R pan-agonist for treating hyperphagia in patients with Prader-Willi Syndrome, required for regulatory approval of its lead asset.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
May 09, 2024
Lead Product(s) : Denatonium Acetate
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II
Sponsor : Cantor Fitzgerald
Deal Size : $85.0 million
Deal Type : Series C Financing

A Study to Evaluate ARD-501 in Patients With Autism Spectrum Disorder
Details : ARD-501 is a drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Autism Spectrum Disorder.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
November 13, 2023

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Lead Product(s) : Amphetamine Sulfate
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Recipient : GRI Bio
Deal Size : $80.0 million
Deal Type : Agreement
Details : Under the agreement, Aardvark will acquire certain assets and intellectual property of the Company that pertain to ADAIR, a proprietary abuse-deterrent formulation of immediate release dextroamphetamine, for the development of certain follow-on pipeline ...
Product Name : ADAIR
Product Type : Miscellaneous
Upfront Cash : Undisclosed
August 23, 2023
Lead Product(s) : Amphetamine Sulfate
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Recipient : GRI Bio
Deal Size : $80.0 million
Deal Type : Agreement

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Lead Product(s) : Denatonium Acetate
Therapeutic Area : Genetic Disease
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ARD-101, is a first-in-class oral composition that has shown promising activity in reducing hunger cravings in clinical studies and promoting weight loss in pre-clinical studies and which is investigated for the treatment of prader-willi yndrome.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
August 03, 2023
Lead Product(s) : Denatonium Acetate
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Denatonium Acetate
Therapeutic Area : Genetic Disease
Study Phase : Phase II
Sponsor : University of California
Deal Size : Inapplicable
Deal Type : Inapplicable
Aardvark Therapeutics Reports Positive Phase II Clinical Data for ARD-101
Details : ARD-101 (denatonium acetate) is a first-in-class oral substantially gut-restricted with minimal systemic exposure yet conveys systemic effects via activation of GLP-1, GLP-2, and which show positive impact on hunger scores in general obesity and Prader-W...
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
June 12, 2023
Lead Product(s) : Denatonium Acetate
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II
Sponsor : University of California
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Denatonium Acetate
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Phase II
Sponsor : University of California, San Diego
Deal Size : Inapplicable
Deal Type : Inapplicable
Study to Evaluate ARD-101 in Adults Receiving Bariatric Surgery
Details : ARD-101 is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Obesity.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
January 31, 2022
Lead Product(s) : Denatonium Acetate
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Phase II
Sponsor : University of California, San Diego
Deal Size : Inapplicable
Deal Type : Inapplicable
