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    [{"orgOrder":0,"company":"7 Hills Pharma","sponsor":"CPRIT","pharmaFlowCategory":"D","therapeuticArea":"Hematology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Funding","leadProduct":"7HP935","moa":"Undisclosed","graph1":"Hematology","graph2":"Preclinical","graph3":"7 Hills Pharma","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Hematology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"7 Hills Pharma \/ CPRIT","highestDevelopmentStatusID":"4","companyTruncated":"7 Hills Pharma \/ CPRIT"},{"orgOrder":0,"company":"7 Hills Pharma","sponsor":"National Institutes of Health","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Vaccine","year":"2022","type":"Funding","leadProduct":"7HP349","moa":"||Amyloid-beta-protein","graph1":"Infections and Infectious Diseases","graph2":"Preclinical","graph3":"7 Hills 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    Find Clinical Drug Pipeline Developments & Deals by 7 Hills Pharma

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                            01

                            7 Hills Pharma

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                            Lead Product(s) : Alintegimod,Ipilimumab,Nivolumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            7 Hills Pharma Safely Doses First Patient in Alintegimod Trial for Solid Tumors

                            Details : 7HP349 (alintegimod), an integrin-targeted agonist, is being investigated in combination with ipililumab and nivolumab in cancer patients who are resistant to PD-1 treatments.

                            Product Name : 7HP349

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            March 09, 2024

                            Lead Product(s) : Alintegimod,Ipilimumab,Nivolumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            7 Hills Pharma

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                            Lead Product(s) : 7HP935

                            Therapeutic Area : Hematology

                            Study Phase : Preclinical

                            Sponsor : CPRIT

                            Deal Size : $4.7 million

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            7 Hills Pharma Receives $4.7MM Grant for Cell/Gene Therapy Technology in the Clinic

                            Details : 7 Hills will advance 7HP935, the Company’s lead first-in-class small molecule to augment CGT, through a Phase I clinical trial.

                            Product Name : 7HP935

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            March 06, 2024

                            Lead Product(s) : 7HP935

                            Therapeutic Area : Hematology

                            Highest Development Status : Preclinical

                            Sponsor : CPRIT

                            Deal Size : $4.7 million

                            Deal Type : Funding

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                            03

                            7 Hills Pharma

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                            Lead Product(s) : Alintegimod

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : CPRIT

                            Deal Size : $13.5 million

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            7 Hills Pharma Surpasses $25MM Milestone in Nondilutive Funding

                            Details : The fundings will be used to advance 7HP349 (alintegimod), its first-in-class oral selective integrin activator into a Phase 1b/2a clinical trial in patients who are resistant to PD-1-based therapies.

                            Product Name : 7HP349

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            May 22, 2023

                            Lead Product(s) : Alintegimod

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : CPRIT

                            Deal Size : $13.5 million

                            Deal Type : Funding

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                            04

                            7 Hills Pharma

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                            Lead Product(s) : Alintegimod

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            7 Hills Pharma Expands Pioneering Patent Portfolio With New Claims Covering Innovative Combination Therapies

                            Details : 7HP349 is 7HP’s lead, clinical-stage integrin agonist. It is a first-in-class, orally delivered small molecule that safely and selectively activates the integrins LFA-1 and VLA-4 to augment the antigen-specific immune response.

                            Product Name : 7HP349

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            September 06, 2022

                            Lead Product(s) : Alintegimod

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

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                            Lead Product(s) : Alintegimod,Undisclosed

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            7 Hills Pharma’s Clinical-stage Novel Immunostimulant 7HP349 Granted FDA Fast Track Designation for Anti-PD-...

                            Details : 7HP349, an allosteric activator of integrins VLA-4 and LFA-1, used in combination with immunotherapy improve effectiveness of potentially any immunotherapeutic, including, but not limited to immune checkpoint inhibitors and infectious disease vaccines.

                            Product Name : 7HP349

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            August 03, 2022

                            Lead Product(s) : Alintegimod,Undisclosed

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

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                            Lead Product(s) : Alintegimod

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Texas Heart Institute

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            New Study Demonstrates Integrin Activation Can Bring the Heat to Cold Melanoma Tumors

                            Details : 7HP349 is 7HP’s lead, clinical-stage integrin agonist. It is a first-in-class, orally delivered small molecule that safely and selectively activates the integrins LFA-1 and VLA-4 to augment the antigen-specific immune response.

                            Product Name : 7HP349

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            May 18, 2022

                            Lead Product(s) : Alintegimod

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Texas Heart Institute

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            7 Hills Pharma

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                            Lead Product(s) : DNA Vaccine,Alintegimod

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Preclinical

                            Sponsor : National Institutes of Health

                            Deal Size : $3.0 million

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            7 Hills Pharma Receives $3MM SBIR Grant from NIAID to Accelerate Novel Vaccine Combination Against Chagas Dise...

                            Details : DNA-based vaccine to protect against Tc infection, which was tested in preclinical models in combination with 7HP’s lead, oral immunostimulant. Results of this initial study, demonstrated that the combination therapy was effective in both prophylactic ...

                            Product Name : Undisclosed

                            Product Type : Vaccine

                            Upfront Cash : Undisclosed

                            January 08, 2022

                            Lead Product(s) : DNA Vaccine,Alintegimod

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Preclinical

                            Sponsor : National Institutes of Health

                            Deal Size : $3.0 million

                            Deal Type : Funding

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                            08

                            7 Hills Pharma

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                            Lead Product(s) : Alintegimod

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            7 Hills Pharma Announces First Healthy Volunteers Dosed in Landmark Phase 1 Trial of Immunostimulant to Improv...

                            Details : 7HP349 is designed to activate integrins, enhancing cell adhesion for stronger immune responses to vaccinations, such as those for COVID-19 and influenza, and immuno-oncology drugs, such as checkpoint inhibitors.

                            Product Name : 7HP349

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            September 11, 2020

                            Lead Product(s) : Alintegimod

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            7 Hills Pharma

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                            Lead Product(s) : Alintegimod

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            7 Hills Pharma Announces Positive Data With Oral Immunostimulant to Improve Effectiveness of COVID-19 Vaccines

                            Details : Preclinical studies reveal 7HP349 significantly increases IgG binding antibodies with a vaccine targeting SARS-CoV-2. The data also suggest 7HP349 can be used as an immunostimulant for any COVID-19 vaccine and has the potential to accelerate immune syste...

                            Product Name : 7HP349

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            July 07, 2020

                            Lead Product(s) : Alintegimod

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            7 Hills Pharma

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                            Lead Product(s) : Alintegimod

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            7 Hills Pharma Announces Coronavirus Vaccine ProgramTargeting At-Risk Elderly

                            Details : 7 Hills Pharma is launching an evaluation of its lead compound 7HP349, a next-generation small molecule integrin activator, as an oral adjuvant with a novel recombinant coonavirus vaccine.

                            Product Name : 7HP349

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            April 15, 2020

                            Lead Product(s) : Alintegimod

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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