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    CAS 4039-32-1
    Also known as: 4039-32-1, Lithium hexamethyldisilazide, Lihmds, Hexamethyldisilazane lithium salt, Lhmds, Lithiumbis(trimethylsilyl)amide
    Molecular Formula
    C6H18LiNSi2
    Molecular Weight
    167.4  g/mol
    InChI Key
    YNESATAKKCNGOF-UHFFFAOYSA-N
    FDA UNII
    RC4N1I108M
    1 2D Structure

    CAS 4039-32-1

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    lithium;bis(trimethylsilyl)azanide
    2.1.2 InChI
    InChI=1S/C6H18NSi2.Li/c1-8(2,3)7-9(4,5)6;/h1-6H3;/q-1;+1
    2.1.3 InChI Key
    YNESATAKKCNGOF-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    [Li+].C[Si](C)(C)[N-][Si](C)(C)C
    2.2 Other Identifiers
    2.2.1 UNII
    RC4N1I108M
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. (lin(sime3)2)

    2. Li Bis(tms)a

    2.3.2 Depositor-Supplied Synonyms

    1. 4039-32-1

    2. Lithium Hexamethyldisilazide

    3. Lihmds

    4. Hexamethyldisilazane Lithium Salt

    5. Lhmds

    6. Lithiumbis(trimethylsilyl)amide

    7. Lithium Hexamethyldisilazane

    8. N-lithiohexamethyldisilazane

    9. Bis(trimethylsilyl)amido Lithium

    10. Lithium Bis(trimethylsilyl)azanide

    11. Lithium;bis(trimethylsilyl)azanide

    12. Lithiohexamethyldisilazane

    13. Bis(trimethylsilyl)amidolithium

    14. Lithium, (bis(trimethylsilyl)amino)-

    15. Lithium Hexamethyldisilazanide

    16. Rc4n1i108m

    17. Silanamine, 1,1,1-trimethyl-n-(trimethylsilyl)-, Lithium Salt

    18. Lithiumbis(trimethylsilyl)amine

    19. Disilazane, 1,1,1,3,3,3-hexamethyl-, Lithium Salt

    20. Lithium Tris(trimethylsilyl)amine

    21. Lithium Bis(trimethylsilyl) Amide

    22. Lithium Bis-(trimethylsilyl)amide

    23. Lithium Bis[trimethylsilyl]amide

    24. Lithium Bistrimethylsilylamide

    25. Lithium Bis-trimethylsilylamide

    26. Mfcd00008261

    27. Silanamine, 1,1,1-trimethyl-n-(trimethylsilyl)-, Lithium Salt (1:1)

    28. Lithium Bis(trimethylsilyl)amide (ca. 26% In Tetrahydrofuran, Ca. 1.3mol/l)

    29. Lithium Bis(trimethylsilyl)amine

    30. Lithiobis(trimethylsilyl)amide; Lithiohexamethyldisilazane; Lithium Bis(trimethylsilyl)amide; Lithium Bis(trimethylsilyl)amide(1-)

    31. Lithium Bis-(trimethylsilyl)-amide

    32. Nsc-252161

    33. Unii-rc4n1i108m

    34. Einecs 223-725-6

    35. Phenylmethyl Carbonate

    36. Nsc 252161

    37. Lin(sime3)2

    38. Lithium Bis(tms) Amide

    39. Lithiumhexamethyidisilazide

    40. Lithiumhexamethyldisilazide

    41. Lin(tms)2

    42. Lithium Hexamethyldisilazid

    43. Lithium Hexamethydisilazide

    44. Lithium Hexamethlydisilazide

    45. Lithiumhexamethyl Disilazide

    46. Lithium Hexamethyidisilazide

    47. Ec 223-725-6

    48. Lithiumbistrimethylsilylamide

    49. Schembl6240

    50. Lithium Hexamethyl-disilazide

    51. Lithium Hexamethyl Disilazide

    52. N-lithio-hexamethyldisilazane

    53. Lithiumbistrimethylsilyl Amide

    54. Lithium Bis-trimethysilylamide

    55. Lithium Hexa Methyl Disilazide

    56. Bis(trimethylsilyl)aminolithium

    57. Lithium Bis Trimethylsilylamide

    58. Lithium Bistrimethylsilyl Amide

    59. Lithium Bis(trimethylsilyl)amid

    60. Lithium Bis(trimethysilyl)amide

    61. Lithium Bis(trimethlsilyl)amide

    62. Lithium Bis(trimethylsily)amide

    63. Bis(trimethylsilyl)amide Lithium

    64. Lithium Bis Trimethylsilyl Amide

    65. Lithium Bis(trimethlysilyl)amide

    66. Dtxsid2044426

    67. Lithium Bis(trimethylsilyl)arnide

    68. Lithium Bis(trimethysilyl) Amide

    69. (bis(trimethylsilyl)amino)lithium

    70. Lithium Bis (trimethylsilyl)amide

    71. Lithium Bis(tri-methylsilyl)amide

    72. Lithium Bis(trimethyl Silyl)amide

    73. Lithium Bis(trimethyl-silyl)amide

    74. Lithium Bis(trimethylsilyl)-amide

    75. Lithium N,n-bistrimethylsilylamide

    76. Ynesatakkcngof-uhfffaoysa-n

    77. (bis(trimethylsilyl)amino) Lithium

    78. Lithium Bis (trimethylsilyl) Amide

    79. Lithium Bis(trimethyl Silyl)-amide

    80. Lithium Bis(trimethyl- Silyl)amide

    81. Lithium Bis-(trimethylsilyl) Amide

    82. Lithium Bis(trimethylsilyl) Azanide

    83. Lithium Hexamethyldisilazide;lihmds

    84. (hexamethyldisilazane)lithium

    85. Amy39452

    86. Bcp21718

    87. Lithium Hexamethyldisilazanate

    88. Lithiobis(trimethylsilyl)amide

    89. Akos015909050

    90. Akos015967096

    91. At25133

    92. Lithium Bis(trimethylsilyl)amide, 97%

    93. Bp-13374

    94. Hexamethyldisilazane Lithium Salt 1m In Thf

    95. Ft-0605921

    96. H0915

    97. Lithiumhexamethyldisilazide1mintetrahydrofuran

    98. S09630

    99. 1,1,1,3,3,3-hexamethyldisilazane Lithium Salt

    100. Lithium Bis(trimethylsilyl)amide, 1m In Toluene

    101. N,n-bis(trimethylsilyl)amine Lithium Salt

    102. A825085

    103. Lithium 1,1,1,3,3,3-hexamethyldisilazan-2-ide

    104. Q219037

    105. J-640310

    106. J-800313

    107. J-802235

    108. Lithium 1, 1, 1, 3,3,3-hexamethyldisilazan-2-ide

    109. Lithium Bis(trimethylsilyl)amide, 1m In Tetrahydrofuran

    110. Hexamethyldisilazane Lithium Salt 1.25m (23-25%) In Thf

    111. (1,1,1-trimethyl-n-(trimethylsilyl)silanaminato)lithium

    112. Lithium Bis(trimethylsilyl)amide, 20%, Ca 1.06m In Thf/eb

    113. Lithium Hexamethyldisilazide, 0.85m In Hexane (19-21 Wt %)

    114. 1,1,1-trimethyl-n-(trimethylsilyl)silanamine Lithium Salt

    115. Lithium Hexamethyldisilazide, 1.25m In Tetrahydrofuran (23-25 Wt %)

    116. Lithium Bis(trimethylsilyl)amide, 0.9-1.1m In Hexane, Packaged In Resealable Chemseal Bottles

    2.4 Create Date
    2005-07-19
    3 Chemical and Physical Properties
    Molecular Weight 167.4 g/mol
    Molecular Formula C6H18LiNSi2
    Hydrogen Bond Donor Count0
    Hydrogen Bond Acceptor Count1
    Rotatable Bond Count2
    Exact Mass g/mol
    Monoisotopic Mass g/mol
    Topological Polar Surface Area1
    Heavy Atom Count10
    Formal Charge0
    Complexity80.9
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
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                                    Atorvastatin
                                    Jiangsu Yutian Pharmaceutical Co., Ltd. is located in Dapu Pharmaceutical Zone of Lianyungang City in Jia...
                                    Jiangsu Yutian Pharmaceutical Co., Ltd. is located in Dapu Pharmaceutical Zone of Lianyungang City in Jiangsu Province. It is a new and high-tech enterprise engaged in research and production of bulk pharmaceutical chemicals, medical high-grade intermediate and other fine chemicals. We make efforts to provide wide customers with superior quality product. Covering an area of 66400 square meters and a construction area of 37600 square meters, our company has 8 synthesis plants, 1 GMP and FDA standard cleaning shop, modern and advanced production equipment, leading grade laboratory and excellent quality control center. In addition, there is outstanding technology development, production and management talents. Due to high quality and superior service, our products have been exported to Japan, South Korea, India and Europe. We sincerely welcome wide customers to visit us and pay guidance on our work! We would like to create brilliant future hand in hand with you!
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                                    Jiangsu Yutian Pharmaceutical Co., ...

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                                      (4R,cis)-1,1-dimethylethyl-6-aminoethyl-2,2- dimethyl-1...

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                                      125995-13-3
                                      Atorvastatin
                                      Jiangsu Yutian Pharmaceutical Co., Ltd. is located in Dapu Pharmaceutical Zone of Lianyungang City in Jia...
                                      Jiangsu Yutian Pharmaceutical Co., Ltd. is located in Dapu Pharmaceutical Zone of Lianyungang City in Jiangsu Province. It is a new and high-tech enterprise engaged in research and production of bulk pharmaceutical chemicals, medical high-grade intermediate and other fine chemicals. We make efforts to provide wide customers with superior quality product. Covering an area of 66400 square meters and a construction area of 37600 square meters, our company has 8 synthesis plants, 1 GMP and FDA standard cleaning shop, modern and advanced production equipment, leading grade laboratory and excellent quality control center. In addition, there is outstanding technology development, production and management talents. Due to high quality and superior service, our products have been exported to Japan, South Korea, India and Europe. We sincerely welcome wide customers to visit us and pay guidance on our work! We would like to create brilliant future hand in hand with you!
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                                      Jiangsu Yutian Pharmaceutical Co., ...

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                                        (4R-cis)-1,1-Dimethylethyl-6-Cyanomethyl-2,2- dimethyl-...

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                                        125971-94-0
                                        Atorvastatin
                                        Jiangsu Yutian Pharmaceutical Co., Ltd. is located in Dapu Pharmaceutical Zone of Lianyungang City in Jia...
                                        Jiangsu Yutian Pharmaceutical Co., Ltd. is located in Dapu Pharmaceutical Zone of Lianyungang City in Jiangsu Province. It is a new and high-tech enterprise engaged in research and production of bulk pharmaceutical chemicals, medical high-grade intermediate and other fine chemicals. We make efforts to provide wide customers with superior quality product. Covering an area of 66400 square meters and a construction area of 37600 square meters, our company has 8 synthesis plants, 1 GMP and FDA standard cleaning shop, modern and advanced production equipment, leading grade laboratory and excellent quality control center. In addition, there is outstanding technology development, production and management talents. Due to high quality and superior service, our products have been exported to Japan, South Korea, India and Europe. We sincerely welcome wide customers to visit us and pay guidance on our work! We would like to create brilliant future hand in hand with you!
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                                        Kimia Biosciences

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                                          (r)-4-propyldihydrofuran-2-(3h)

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                                          63095-51-2
                                          Brivaracetam
                                          Kimia Biosciences, established in 1993, is focused on manufacturing bulk drugs for various therapeutic se...
                                          Kimia Biosciences, established in 1993, is focused on manufacturing bulk drugs for various therapeutic segments. With a strong emphasis on excellence and advanced technologies, Kimia aims to become a globally recognized company in both APIs and FDFs while upholding clean business practices. Kimia's state-of-the-art facilities at Village Bhondsi, Gurugram enable it to produce a wide range of APIs. Kimia also plans to establish its own facilities for lifestyle segments, adhering to international regulatory standards. Kimia aims to provide the best pharmaceutical products and support to consumers and healthcare professionals.
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                                          Luna Chemicals

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                                            (4R-Cis)-1,1-Dimethylethyl-6-[2-Fuorophenyl]-5-(1-Methy...

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                                            125971-94-0
                                            Atorvastatin
                                            LUNA Chemicals Co.,Ltd. markets and manufactures world-class quality Active Pharmaceutical Ingredients an...
                                            LUNA Chemicals Co.,Ltd. markets and manufactures world-class quality Active Pharmaceutical Ingredients and intermediate chemicals for generic pharmaceutical companies. Our Development Team focus strategically on the core therapeutic areas: cardiovascular, anti-depressant, allergic, healthcare and plant extraction. We provide technical support and efficient regulatory documentation for manufacturers, intellectual property(IP) was always carefully considered as well. We also provide excellent outsourcing services to customers and laboratory support.
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                                            Luna Chemicals

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                                              (4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxa...

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                                              125971-94-0
                                              Atorvastatin
                                              LUNA Chemicals Co.,Ltd. markets and manufactures world-class quality Active Pharmaceutical Ingredients an...
                                              LUNA Chemicals Co.,Ltd. markets and manufactures world-class quality Active Pharmaceutical Ingredients and intermediate chemicals for generic pharmaceutical companies. Our Development Team focus strategically on the core therapeutic areas: cardiovascular, anti-depressant, allergic, healthcare and plant extraction. We provide technical support and efficient regulatory documentation for manufacturers, intellectual property(IP) was always carefully considered as well. We also provide excellent outsourcing services to customers and laboratory support.
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                                              Luna Chemicals

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                                                (4R,6R)-t-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxa...

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                                                125995-13-3
                                                Atorvastatin
                                                LUNA Chemicals Co.,Ltd. markets and manufactures world-class quality Active Pharmaceutical Ingredients an...
                                                LUNA Chemicals Co.,Ltd. markets and manufactures world-class quality Active Pharmaceutical Ingredients and intermediate chemicals for generic pharmaceutical companies. Our Development Team focus strategically on the core therapeutic areas: cardiovascular, anti-depressant, allergic, healthcare and plant extraction. We provide technical support and efficient regulatory documentation for manufacturers, intellectual property(IP) was always carefully considered as well. We also provide excellent outsourcing services to customers and laboratory support.
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                                                Morepen Laboratories

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                                                (4R-Cis)-1,1-Dimethylethyl-6-[2-[2-(4-Fluorophenyl)-5-(...

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                                                125971-95-1
                                                Atorvastatin
                                                Morepen Laboratories Ltd.’ is 31 years old company. Went to public in 1993. Manufacturer and Exporter o...
                                                Morepen Laboratories Ltd.’ is 31 years old company. Went to public in 1993. Manufacturer and Exporter of complex and high margins molecules (APIs/Intermediates) for regulated markets of USA, Europe, Russia, Canada and also for non-regulated markets. The first Morepen manufacturing plant was set up on the foothills of the Himalayas in the idyllic surroundings of Parwanoo. The large and spread-out facility is USDFA approved for manufacture of Loratadine, an anti-allergy drug- internationally known as Claritin.
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                                                Saintsun Pharma

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                                                  Ethyl S-4-chloro-3-hydroxybutyrate

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                                                  86728-85-0
                                                  Atorvastatin
                                                  SAINTSUN PHARMA, we are engaging mainly in the manufacturing and distributing APIs, Pharmaceutical Interm...
                                                  SAINTSUN PHARMA, we are engaging mainly in the manufacturing and distributing APIs, Pharmaceutical Intermediates, Chemicals, Formulations, Medical supplies, etc... With a self-owned brand of "SAINTSUN PHARMA", after more than 12 years efforts, our products are successfully expanded to different continents like Asia, South America, Africa more than 35 countries and regions.
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                                                  Sandoo Pharmaceuticals and Chemcial...

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                                                    (2S)-2-Aminobutanamide Hydrochloride

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                                                    7682-20-4
                                                    Brivaracetam
                                                    Sandoo Pharmaceuticals and Chemcials Co.,Ltd was established in 2009, with a young and active team, locat...
                                                    Sandoo Pharmaceuticals and Chemcials Co.,Ltd was established in 2009, with a young and active team, located in Ningbo, China. Specializes in exporting and importing pharmaceutical intermediates and chemical products as well as active pharmaceutical ingredients.
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                                                    Sanpra Synthesis

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                                                      (S)-(+)-4-Benzyl-2-Oxazolidinone

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                                                      90719-32-7
                                                      Brivaracetam
                                                      Sanpra Synthesis strongly believes that with its expertise and innovative pharmaceutical business backgro...
                                                      Sanpra Synthesis strongly believes that with its expertise and innovative pharmaceutical business background, it is aptly positioned for APIs and intermediates manufacturing and outsourcing for the global market. We also undertake custom synthesis and contract manufacturing. Setting up multiple c GMP-manufacturing facility and world-class R&D center located in Vizag APSEZ De-notified area with well connected to road, rail, and air enabling cargo movement to the nearest transport facility in commercial production from January 2020.
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                                                      Shanghai Daishang Chemical

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                                                        (R)-4-Propyldihydrofuran-2(3H)-one

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                                                        63095-51-2
                                                        Brivaracetam
                                                        Shanghai Daishang Chemical Co., Ltd. established in January 2005, sticking to the guiding principle "Tech...
                                                        Shanghai Daishang Chemical Co., Ltd. established in January 2005, sticking to the guiding principle "Technical innovation, Quality Orientation", we practice best of technology innovation, optimized management and robust service system for our customers. Daishang Chem is specialized in the researching, manufacturing, sales and marketing of API & Its Intermediates as well as other Fine Chemicals, taking great advantages of professional and proficient staff, based on three chemical manufacturing sites and one GMP manufacturing workshops in Liaoning, Henan and Zhejiang provinces, and one R&D laboratory in Zhangjiang Hi-tech Park.
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                                                        Shenzhen HwaGen Pharmaceutical

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                                                          (+)-(R)-4-propyl-4,5-dihydrofuran-2(3H)-one

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                                                          63095-51-2
                                                          Brivaracetam
                                                          Shenzhen HwaGen Pharmaceutical Co., Ltd. (HwaGen Pharma) was founded in December of 2015 under the leader...
                                                          Shenzhen HwaGen Pharmaceutical Co., Ltd. (HwaGen Pharma) was founded in December of 2015 under the leadership of a “National 1000 Talents Program” expert. By leveraging its core competency in chiral synthesis, enzymatic catalysis and continuous flow micro reactor, HwaGen Pharmaceutical is dedicated to development and manufacturing of specialty and niche intermediates and APIs covering various therapeutic areas including oncology, antiviral and respiratory, delivering high value-added and affordable products for global pharmaceutical industry. Equipments for Analysis & Test include Tabletop NMR, LC-MS, GC, HPLC etc.
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                                                          Smilax Laboratories Limited

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                                                          2-(2-(4-Fluorophenyl)-2-oxo-1- phenylethyl)-4-methyl-3-...

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                                                          125971-96-2
                                                          Atorvastatin
                                                          Smilax Laboratories Limited is a research-driven, vertically integrated pharmaceutical company manufactur...
                                                          Smilax Laboratories Limited is a research-driven, vertically integrated pharmaceutical company manufacturing Active Pharmaceutical Ingredients, API Intermediates and NDDS/Pellets for the generics market across the world. Set up in 2005, Smilax has emerged a reliable supplier of generic products in the global market today. Set up in 2005, Smilax has emerged a reliable supplier of generic products in the global market today.Set up in 2005, Smilax has emerged a reliable supplier of generic products in the global market today. Smilax manufactures APIs and API Intermediates at its state-of-the-art manufacturing facilities located at Hyderabad, Telangana and Visakhapatnam, Andhra Pradesh, India. Supported by a highly qualified and competent technical team, and endowed with strengths in research and development, Smilax continues to expand its presence in the world of pharmaceuticals.
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                                                          Vijayasri Organics Limited

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                                                          (±)-4-Fluoro-a-(2-methyl-1-oxopropyl)-g-oxo-N, b-diphe...

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                                                          125971-96-2
                                                          Atorvastatin
                                                          We introduce ourselves as manufacturer of Active Pharmaceutical Ingredients (API) and intermediates with ...
                                                          We introduce ourselves as manufacturer of Active Pharmaceutical Ingredients (API) and intermediates with a professional approach that is aimed at finest results. We have etched a respectable place in the industry with proven expertise in manufacturing a wide spectrum of products. Vijayasri today is one of the prominent manufacturers of Active Pharmaceutical Ingredients (API) and intermediates. Our excellent Performance in Contract manufacturing over the years has also earned us the status of a trustable name in the pharmaceutical industry.
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                                                          euroapi-2024-05-06

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                                                          Minakem offers CDMO services for API & HPAPI, generics, regulatory expertise, track record performance & FDA & GMP certifications.

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