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    CAS 23680-84-4
    Also known as: 23680-84-4, 2-chloro-6,7-dimethoxyquinazolin-4-amine, 2-chloro-4-amino-6,7-dimethoxyquinazoline, 2-chloro-6,7-dimethoxy-4-quinazolinamine, 4-quinazolinamine, 2-chloro-6,7-dimethoxy-, 2-chloro-4-amino-6,7-dimethoxy quinazoline
    Molecular Formula
    C10H10ClN3O2
    Molecular Weight
    239.66  g/mol
    InChI Key
    HWIIAAVGRHKSOJ-UHFFFAOYSA-N
    FDA UNII
    FG7Z4T71Y4
    1 2D Structure

    CAS 23680-84-4

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    2-chloro-6,7-dimethoxyquinazolin-4-amine
    2.1.2 InChI
    InChI=1S/C10H10ClN3O2/c1-15-7-3-5-6(4-8(7)16-2)13-10(11)14-9(5)12/h3-4H,1-2H3,(H2,12,13,14)
    2.1.3 InChI Key
    HWIIAAVGRHKSOJ-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    COC1=C(C=C2C(=C1)C(=NC(=N2)Cl)N)OC
    2.2 Other Identifiers
    2.2.1 UNII
    FG7Z4T71Y4
    2.3 Synonyms
    2.3.1 Depositor-Supplied Synonyms

    1. 23680-84-4

    2. 2-chloro-6,7-dimethoxyquinazolin-4-amine

    3. 2-chloro-4-amino-6,7-dimethoxyquinazoline

    4. 2-chloro-6,7-dimethoxy-4-quinazolinamine

    5. 4-quinazolinamine, 2-chloro-6,7-dimethoxy-

    6. 2-chloro-4-amino-6,7-dimethoxy Quinazoline

    7. 2-chloro-4-amino-6,7-dimethoxy-quinazoline

    8. Mfcd00051734

    9. 2680-84-4

    10. Fg7z4t71y4

    11. 2-chloro-6,7-dimethoxy-4-aminoquinazoline

    12. 2-chloro-6,7-dimethoxyquinazolin-4-ylamine

    13. 4-amino-2-chloro-6,7-dimethoxy Quinazoline

    14. Sr-01000197509

    15. Quinazolinamine

    16. Unii-fg7z4t71y4

    17. Prazosin Impurity A

    18. Einecs 245-821-7

    19. Doxazosin Impurity F

    20. Terazosin Impurity A

    21. Ec 245-821-7

    22. Dsstox_cid_31483

    23. Dsstox_rid_97368

    24. Dsstox_gsid_57694

    25. Bidd:gt0452

    26. Schembl611438

    27. 10-propoxy-decanoicacid

    28. Chembl3561187

    29. Dtxsid3057694

    30. (e/z)-trelnarizine Dihydrochloride

    31. Albb-005949

    32. Bcp28790

    33. Zinc2028665

    34. Tox21_113801

    35. Stk503641

    36. Akos000264944

    37. Ac-5334

    38. Ps-3289

    39. 4amino-2-chloro6,7-dimethoxyquinazoline

    40. Ncgc00253677-01

    41. 4-amino-2chloro-6,7-dimethoxyquinazoline

    42. Sy008892

    43. 4-amino-2-chloro-6,7-dimethoxyquinazolin

    44. 2-chloro-6,7-dimethoxy Quinazolin-4-amine

    45. 2-chloro-6,7-dimethoxyquinazoline-4-amine

    46. 4-amino-2-chloro-6,7-dimethoxy-quinzoline

    47. 4-amino-2-chloro-6,7-dimethoxyquinozoline

    48. 4-amino-2chloro-6,7-dimethoxy Quinazoline

    49. Cas-23680-84-4

    50. Db-046221

    51. 2-chloro-4-amino-6,7-dimethoxyquin-azoline

    52. 2-chloro-6,7-dimethoxy-4-quinazolinamine #

    53. 4-amino-2-chloro-6,7-bismethoxyquinazoline

    54. 4-amino-2-chloro-6,7-dimethoxy-quinazoline

    55. Am20030412

    56. Bb 0257419

    57. Cs-0127991

    58. Ft-0620860

    59. Doxazosin Related Compound C [usp-rs]

    60. En300-66004

    61. 80c844

    62. 4-amino-2-chloro-6,7-dimethoxyquinazoline, 95%

    63. Ae-848/31926053

    64. Doxazosin Mesilate Impurity F [ep Impurity]

    65. Doxazosin Related Compound C [usp Impurity]

    66. Sr-01000197509-1

    67. Sr-01000197509-2

    68. W-107385

    69. Prazosin Hydrochloride Impurity A [ep Impurity]

    70. Q27277971

    71. Quinazoline, 4-amino-2-chloro-6,7-dimethoxy-

    72. Alfuzosin Hydrochloride Impurity B [ep Impurity]

    73. Z1741965684

    74. Doxazosin Impurity F, European Pharmacopoeia (ep) Reference Standard

    75. Terazosin Hydrochloride Dihydrate Impurity A [ep Impurity]

    76. Terazosin Impurity A, European Pharmacopoeia (ep) Reference Standard

    77. 4-amino-2-chloro-6,7-dimethoxyquinazoline, Puriss., >=99.0% (hplc)

    78. Doxazosin Related Compound C, United States Pharmacopeia (usp) Reference Standard

    2.4 Create Date
    2005-03-27
    3 Chemical and Physical Properties
    Molecular Weight 239.66 g/mol
    Molecular Formula C10H10ClN3O2
    XLogP32.2
    Hydrogen Bond Donor Count1
    Hydrogen Bond Acceptor Count5
    Rotatable Bond Count2
    Exact Mass239.0461543 g/mol
    Monoisotopic Mass239.0461543 g/mol
    Topological Polar Surface Area70.3 Ų
    Heavy Atom Count16
    Formal Charge0
    Complexity244
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
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                                        Doxazosin Mesylate
                                        LUNA Chemicals Co.,Ltd. markets and manufactures world-class quality Active Pharmaceutical Ingredients an...
                                        LUNA Chemicals Co.,Ltd. markets and manufactures world-class quality Active Pharmaceutical Ingredients and intermediate chemicals for generic pharmaceutical companies. Our Development Team focus strategically on the core therapeutic areas: cardiovascular, anti-depressant, allergic, healthcare and plant extraction. We provide technical support and efficient regulatory documentation for manufacturers, intellectual property(IP) was always carefully considered as well. We also provide excellent outsourcing services to customers and laboratory support.
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                                        Medilux Laboratories

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                                          1,4-Benzodioxan-2-carboxylic acid

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                                          3663-80-7
                                          Doxazosin Mesylate
                                          Medilux Laboratories has been providing quality back-end support to the pharmaceutical industry at large ...
                                          Medilux Laboratories has been providing quality back-end support to the pharmaceutical industry at large since our inception in 1988. Our resources are dedicated to promoting better health through products that offer superior value. Located at Pithampur, Madhya Pradesh, Medilux Laboratories has been committed to strategic research, delivering a complex range of chemistries that are globally benchmarked. Our products and services are rapidly making strides in the global pharmaceutical space, giving us the impetus to constantly strive for excellence in addition to providing quality customer service. Supported by a workforce of over 150 dedicate
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                                          Medilux Laboratories

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                                            1-[(2,3-Dihydro-1,4-benzodioxin-2-yl)carbonyl]-piperazi...

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                                            70918-00-2
                                            Doxazosin Mesylate
                                            Medilux Laboratories has been providing quality back-end support to the pharmaceutical industry at large ...
                                            Medilux Laboratories has been providing quality back-end support to the pharmaceutical industry at large since our inception in 1988. Our resources are dedicated to promoting better health through products that offer superior value. Located at Pithampur, Madhya Pradesh, Medilux Laboratories has been committed to strategic research, delivering a complex range of chemistries that are globally benchmarked. Our products and services are rapidly making strides in the global pharmaceutical space, giving us the impetus to constantly strive for excellence in addition to providing quality customer service. Supported by a workforce of over 150 dedicate
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                                            Medilux Laboratories

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                                              Ethyl-1,4-benzodioxane-2- carboxylate

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                                              4739-94-0
                                              Doxazosin Mesylate
                                              Medilux Laboratories has been providing quality back-end support to the pharmaceutical industry at large ...
                                              Medilux Laboratories has been providing quality back-end support to the pharmaceutical industry at large since our inception in 1988. Our resources are dedicated to promoting better health through products that offer superior value. Located at Pithampur, Madhya Pradesh, Medilux Laboratories has been committed to strategic research, delivering a complex range of chemistries that are globally benchmarked. Our products and services are rapidly making strides in the global pharmaceutical space, giving us the impetus to constantly strive for excellence in addition to providing quality customer service. Supported by a workforce of over 150 dedicate
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                                              Medilux Laboratories

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                                                1-[(2,3-Dihydro-1,4-benzodioxin-2-yl)carbonyl]-piperazi...

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                                                70918-00-2
                                                Doxazosin Mesylate
                                                Medilux Laboratories has been providing quality back-end support to the pharmaceutical industry at large ...
                                                Medilux Laboratories has been providing quality back-end support to the pharmaceutical industry at large since our inception in 1988. Our resources are dedicated to promoting better health through products that offer superior value. Located at Pithampur, Madhya Pradesh, Medilux Laboratories has been committed to strategic research, delivering a complex range of chemistries that are globally benchmarked. Our products and services are rapidly making strides in the global pharmaceutical space, giving us the impetus to constantly strive for excellence in addition to providing quality customer service. Supported by a workforce of over 150 dedicate
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                                                RR LIFESCIENCES

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                                                  3-(Methylamino)-propionitrile 98%

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                                                  693-05-0
                                                  Alfuzosin HCl
                                                  RR LIFESCIENCES manufactures products purely by organic synthesis to offer its customers a choice of prod...
                                                  RR LIFESCIENCES manufactures products purely by organic synthesis to offer its customers a choice of products in their areas. Our facilities are equipped with a range of reactor sizes, glass lined reactors and S.S. Reactors, some reactors are capable of operating at high extreme temperature. Other equipments includes Centrifuges, Vacuum Tray Drier, Multi Mills, Tray Drier, in clean finishing suites. All Our facilities are GMP complaint, designed to maintain the highest standards of safety. Our R&D scale-up capabilities from lab scale to commercialization. Our team of experts interacts with our customers from the initial stages of the project to ensure successful completion of the project. We follow stringent quality assurance norms and it has the domain expertise and state of art of facilities to develop analytical methods for evaluating quality of raw materials, intermediates and final products. Our R&D scale-up capabilities from lab scale to commercialization. Our team of experts interacts with our customers from the initial stages of the project to ensure successful completion of the project. We follow stringent quality assurance norms and it has the domain expertise and state of art of facilities to develop analytical methods for evaluating quality of raw materials, intermediates and final products.
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                                                  Shamrock Medicaments

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                                                    1,1-carbonyldiimidazole

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                                                    530-62-1
                                                    Alfuzosin HCl
                                                    Shamrock Medicaments Ltd, formerly known as Doctor Lifeline Remedies India Ltd, has an intriguing evoluti...
                                                    Shamrock Medicaments Ltd, formerly known as Doctor Lifeline Remedies India Ltd, has an intriguing evolution. Established within the robust Shamrock Group in 2001 with a hefty $35 million investment, its inception aimed to cater to the global pharmaceutical market by leveraging India's capabilities. Over time, the company diversified its offerings, expanding into custom manufacturing of pharmaceutical raw materials, intermediates, and chemicals pertinent to the pharmaceutical industry. This strategic expansion likely enabled Shamrock Medicaments Ltd to cement its position as a significant player in the pharmaceutical landscape.
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                                                    Shree Ganesh Remedies

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                                                      2-Furoic Acid

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                                                      88-14-2
                                                      Prazosin Hydrochloride
                                                      Shree Ganesh Remedies is established Since 1995 with an aim to manufacture, supply and export best qualit...
                                                      Shree Ganesh Remedies is established Since 1995 with an aim to manufacture, supply and export best quality of Pharmaceutical-intermediates, Bulk drugs and Speciality Chemicals to cater the needs of pharmaceutical companies and drug companies for research and product development purpose
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                                                      Shree Ganesh Remedies

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                                                        2-Furoyl Chloride

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                                                        527-69-5
                                                        Terazosin
                                                        Shree Ganesh Remedies is established Since 1995 with an aim to manufacture, supply and export best qualit...
                                                        Shree Ganesh Remedies is established Since 1995 with an aim to manufacture, supply and export best quality of Pharmaceutical-intermediates, Bulk drugs and Speciality Chemicals to cater the needs of pharmaceutical companies and drug companies for research and product development purpose
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                                                        Shree Ganesh Remedies

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                                                          2-Furoyl Chloride

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                                                          527-69-5
                                                          Prazosin Hydrochloride
                                                          Shree Ganesh Remedies is established Since 1995 with an aim to manufacture, supply and export best qualit...
                                                          Shree Ganesh Remedies is established Since 1995 with an aim to manufacture, supply and export best quality of Pharmaceutical-intermediates, Bulk drugs and Speciality Chemicals to cater the needs of pharmaceutical companies and drug companies for research and product development purpose
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                                                          Shree Ganesh Remedies

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                                                            Tetrahydro-2-furoic acid

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                                                            16874-33-2
                                                            Terazosin
                                                            Shree Ganesh Remedies is established Since 1995 with an aim to manufacture, supply and export best qualit...
                                                            Shree Ganesh Remedies is established Since 1995 with an aim to manufacture, supply and export best quality of Pharmaceutical-intermediates, Bulk drugs and Speciality Chemicals to cater the needs of pharmaceutical companies and drug companies for research and product development purpose
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                                                            Shree Ganesh Remedies

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                                                              2-Furoic Acid

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                                                              88-14-2
                                                              Terazosin
                                                              Shree Ganesh Remedies is established Since 1995 with an aim to manufacture, supply and export best qualit...
                                                              Shree Ganesh Remedies is established Since 1995 with an aim to manufacture, supply and export best quality of Pharmaceutical-intermediates, Bulk drugs and Speciality Chemicals to cater the needs of pharmaceutical companies and drug companies for research and product development purpose
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                                                              Shree Ganesh Remedies

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                                                                Tetrahydro-2-furoic acid

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                                                                16874-33-2
                                                                Alfuzosin HCl
                                                                Shree Ganesh Remedies is established Since 1995 with an aim to manufacture, supply and export best qualit...
                                                                Shree Ganesh Remedies is established Since 1995 with an aim to manufacture, supply and export best quality of Pharmaceutical-intermediates, Bulk drugs and Speciality Chemicals to cater the needs of pharmaceutical companies and drug companies for research and product development purpose
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                                                                Srini Pharmaceuticals

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                                                                • FDA
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                                                                Doxazosin Mesylate

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                                                                70918-00-2
                                                                Doxazosin Mesylate
                                                                Srini Pharmaceuticals Pvt. Ltd., was established in 1995. USFDA, TGA and KFDA approved fully integrated g...
                                                                Srini Pharmaceuticals Pvt. Ltd., was established in 1995. USFDA, TGA and KFDA approved fully integrated global pharmaceutical company, located just about 60 KM's away from the Pharma Capital of India, Hyderabad. Our manufacturing facility has five fully equipped production blocks with most efficient functional utilities with multiple clean rooms having the ability to produce 10 API's at a time, supported by central quality control laborites with all sophisticated instruments by maintaining complete QMS.
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                                                                fermion-oy-2024-05-13

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                                                                Inke S.A: APIs manufacturing plant.

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