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CAS 2033-24-1
Also known as: 2033-24-1, Meldrum's acid, Isopropylidene malonate, Meldrums acid, 1,3-dioxane-4,6-dione, 2,2-dimethyl-, 2,2-dimethyl-1,3-dioxan-4,6-dione
Molecular Formula
C6H8O4
Molecular Weight
144.12  g/mol
InChI Key
GXHFUVWIGNLZSC-UHFFFAOYSA-N
FDA UNII
DD139RP1SC

1 2D Structure

CAS 2033-24-1

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2,2-dimethyl-1,3-dioxane-4,6-dione
2.1.2 InChI
InChI=1S/C6H8O4/c1-6(2)9-4(7)3-5(8)10-6/h3H2,1-2H3
2.1.3 InChI Key
GXHFUVWIGNLZSC-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC1(OC(=O)CC(=O)O1)C
2.2 Other Identifiers
2.2.1 UNII
DD139RP1SC
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Cyclic Isopropylidene Malonate

2. Meldrum's Acid

2.3.2 Depositor-Supplied Synonyms

1. 2033-24-1

2. Meldrum's Acid

3. Isopropylidene Malonate

4. Meldrums Acid

5. 1,3-dioxane-4,6-dione, 2,2-dimethyl-

6. 2,2-dimethyl-1,3-dioxan-4,6-dione

7. Malonic Acid Cyclic Isopropylidene Ester

8. Cyclic Isopropylidene Malonate

9. Malonic Acid, Cyclic Isopropylidene Ester

10. Cycl-isopropylidene Malonate

11. 2,2-dimethyl-m-dioxane-4,6-dione

12. Mfcd00006638

13. Nsc 71902

14. 2,2-dimethyl-4,6-dioxo-m-dioxane

15. Ai3-39039

16. M-dioxane-4,6-dione, 2,2-dimethyl-

17. 2,2-dimethyl-4,6-dioxo-1,3-dioxane

18. Dd139rp1sc

19. Nsc-71902

20. Nsc688343

21. Nsc-688343

22. 2,2-dimethyl-[1,3]dioxane-4,6-dione

23. Sub-isopropyl Malonate

24. Meldrumic Acid

25. Meldrum Acid

26. Einecs 217-992-8

27. Unii-dd139rp1sc

28. Brn 0117310

29. Meidrum's Acid

30. Meldrum\'s Acid

31. 2,6-dione

32. 2,2-propanediol Cyclic Malonate

33. Meldrum Inverted Exclamation Mark S Acid

34. Meldrum?s Acid-13c

35. 2,6-dioxo-m-dioxane

36. Iso-propylidene Malonate

37. Ec 217-992-8

38. Schembl5976

39. Meldrum's Acid [mi]

40. 5-19-05-00008 (beilstein Handbook Reference)

41. 1,6-dione, 2,2-dimethyl-

42. M-dioxane-4, 2,2-dimethyl-

43. Dtxsid7051846

44. Act03379

45. Albb-013484

46. Cs-d1154

47. Dimethyl-[1,3]dioxane-4,6-dione

48. Nsc71902

49. Str00259

50. Zinc1697324

51. Cx1199

52. Stk397458

53. 2,2-dimethyl-1,3-dioxane-4,6dione

54. 2,2-dimethyl-1,3-dioxane4,6-dione

55. 2,2dimethyl-1,3-dioxane-4,6-dione

56. Akos000119035

57. Ab00787

58. Ac-2044

59. 2,2 Dimethyl-1,3 Dioxane-4,6 Dione

60. 2.2-dimethyl-1,3-dioxane-4,6-dione

61. 4,6-diketo-2,2-dimethyl-1,3-dioxane

62. 2.2-dimethyl-[1,3]dioxane-4,6-dione

63. Sy001708

64. 2, 2-dimethyl-1,3-dioxane-4, 6-dione

65. 2,2-dimethyl-[1,3]-dioxan-4,6-dione

66. 2,2-dimethyl-[1,3]-dioxane-4,6-dione

67. Am20090153

68. Bb 0262989

69. Ft-0627487

70. Ft-0670985

71. M0799

72. 2,2-dimethyl-1,3-dioxane-4,6-dione, 98%

73. 33d241

74. Q421283

75. W-107630

76. F3096-1700

77. Z1258943352

78. Malonic Acid Cyclic Isopropylidene Ester, Meldrum's Acid, Cycl-isopropylidene Malonate

2.4 Create Date
2005-03-26
3 Chemical and Physical Properties
Molecular Weight 144.12 g/mol
Molecular Formula C6H8O4
XLogP30.6
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count0
Exact Mass144.04225873 g/mol
Monoisotopic Mass144.04225873 g/mol
Topological Polar Surface Area52.6 Ų
Heavy Atom Count10
Formal Charge0
Complexity164
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
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Sitagliptin Phosphate
Ningbo Zhenlei Chemical Co.,ltd. located in ningbo city, zhejiang province. We are specializes in R&D, ma...
Ningbo Zhenlei Chemical Co.,ltd. located in ningbo city, zhejiang province. We are specializes in R&D, manufacturing and marketing. Our main product is R-3-amino-1-butanol, Sitagliptin, Sitagliptin phosphate monohydrate. With strong experience and network in Pharmaceutical and Agrochemical, across the globe, Zhenlei is your ideal partner for development of multi-scale synthesis projects as well as manufacturing activities, by ensuring reliable sourcing of raw materials, at competitive pricing and suitable packaging.
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486460-00-8
Sitagliptin Phosphate
Ningbo Zhenlei Chemical Co.,ltd. located in ningbo city, zhejiang province. We are specializes in R&D, ma...
Ningbo Zhenlei Chemical Co.,ltd. located in ningbo city, zhejiang province. We are specializes in R&D, manufacturing and marketing. Our main product is R-3-amino-1-butanol, Sitagliptin, Sitagliptin phosphate monohydrate. With strong experience and network in Pharmaceutical and Agrochemical, across the globe, Zhenlei is your ideal partner for development of multi-scale synthesis projects as well as manufacturing activities, by ensuring reliable sourcing of raw materials, at competitive pricing and suitable packaging.
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764667-65-4
Sitagliptin Phosphate
Ocimum Labs was founded in 2018 and started its R&D activities with a cutting-edge facility. The Hyderaba...
Ocimum Labs was founded in 2018 and started its R&D activities with a cutting-edge facility. The Hyderabad-based firm focuses on process research and development, with a particular emphasis on choosing an API portfolio with a wide range of applications for the global pharma market. It provides a wide variety of integrated products and services. By offering timely and high-quality support, Ocimum Labs hopes to become a strategic partner to global pharma firms and deliver high-quality, cost effective key starting materials, intermediates and APIs. It intends to build a manufacturing facility with a 230KL capacity in Visakhapatnam, India.
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Sitagliptin Phosphate
OctaneX Labs is a leading intermediates and Active Pharmaceutical Ingredients (API) manufacturing company...
OctaneX Labs is a leading intermediates and Active Pharmaceutical Ingredients (API) manufacturing company specializing in the development of innovative processes for the synthesis of a wide range of products. We also undertake custom pharmaceutical services and contract Research Synthesis. We are commited to create better quality of life by being at the forefront of research, manufacturing and marketing of high quality API'S.As a growing organization, we are aware that we can’t achieve our goals singly. We collaborate and work in unison with a large number of reputed and like-minded partners
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Sitagliptin Phosphate
Prajna is an innovation driven pharmaceutical company. We dedicated to Research, Process development and ...
Prajna is an innovation driven pharmaceutical company. We dedicated to Research, Process development and Manufacturing APIs and Advanced Intermediates for Active Pharmaceutical Ingredients (APIs) for the global pharmaceutical companies. It provides value-added services in Contract Research, Custom Synthesis, and Specialties Scientific technology (Green Process, APIs Process Development, Polymorphism, Crystallisation and Purification) for Pharmaceutical and Life Sciences industry.
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25952-53-8
Sitagliptin Phosphate
We are a top producer of Pharmaceutical Intermediates, Specialty Chemicals, and More, with origins dating...
We are a top producer of Pharmaceutical Intermediates, Specialty Chemicals, and More, with origins dating back to 1998. Globally renowned for its Organic Compounds, Inorganic Compounds, Industrial Acids, Industrial Chemicals, Zinc Acetates, Calcium Chloride Dihydrates, Speciality Chemicals, and other products, Sagar Life Science Private Limited is a customer-centric business with a primary focus on innovations, quality, and customization. Since sustainability is among our core values, we concentrate on improving the efficiency of our processes to manufacture sustainable results.
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4039-32-1
Atorvastatin
Sanpra Synthesis strongly believes that with its expertise and innovative pharmaceutical business backgro...
Sanpra Synthesis strongly believes that with its expertise and innovative pharmaceutical business background, it is aptly positioned for APIs and intermediates manufacturing and outsourcing for the global market. We also undertake custom synthesis and contract manufacturing. Setting up multiple c GMP-manufacturing facility and world-class R&D center located in Vizag APSEZ De-notified area with well connected to road, rail, and air enabling cargo movement to the nearest transport facility in commercial production from January 2020.
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Sitagliptin Phosphate
Haorui, established in 1997, is a manufacturer and supplier of APIs, intermediates, veterinary and food a...
Haorui, established in 1997, is a manufacturer and supplier of APIs, intermediates, veterinary and food additives. Meanwhile, it is assisting global pharmaceutical companies to get the domestic registration of their finished dosage for their international expansion. Our USFDA approved products Flumazenil, Granisetron HCl, Granisetron Base, Docetaxel Anhydrous, Irinotecan HCl, Dasatinib Monohydrate, Oxaliplatin and Temozolomide have been recognized by our customers globally. In addition, our Amisulpride API acquired CEP, UK GMP & USDMF.
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762240-92-6
Sitagliptin Phosphate
Smilax Laboratories Limited is a research-driven, vertically integrated pharmaceutical company manufactur...
Smilax Laboratories Limited is a research-driven, vertically integrated pharmaceutical company manufacturing Active Pharmaceutical Ingredients, API Intermediates and NDDS/Pellets for the generics market across the world. Set up in 2005, Smilax has emerged a reliable supplier of generic products in the global market today. Set up in 2005, Smilax has emerged a reliable supplier of generic products in the global market today.Set up in 2005, Smilax has emerged a reliable supplier of generic products in the global market today. Smilax manufactures APIs and API Intermediates at its state-of-the-art manufacturing facilities located at Hyderabad, Telangana and Visakhapatnam, Andhra Pradesh, India. Supported by a highly qualified and competent technical team, and endowed with strengths in research and development, Smilax continues to expand its presence in the world of pharmaceuticals.
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Atorvastatin
Smilax Laboratories Limited is a research-driven, vertically integrated pharmaceutical company manufactur...
Smilax Laboratories Limited is a research-driven, vertically integrated pharmaceutical company manufacturing Active Pharmaceutical Ingredients, API Intermediates and NDDS/Pellets for the generics market across the world. Set up in 2005, Smilax has emerged a reliable supplier of generic products in the global market today. Set up in 2005, Smilax has emerged a reliable supplier of generic products in the global market today.Set up in 2005, Smilax has emerged a reliable supplier of generic products in the global market today. Smilax manufactures APIs and API Intermediates at its state-of-the-art manufacturing facilities located at Hyderabad, Telangana and Visakhapatnam, Andhra Pradesh, India. Supported by a highly qualified and competent technical team, and endowed with strengths in research and development, Smilax continues to expand its presence in the world of pharmaceuticals.
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Sitagliptin Phosphate
Smilax Laboratories Limited is a research-driven, vertically integrated pharmaceutical company manufactur...
Smilax Laboratories Limited is a research-driven, vertically integrated pharmaceutical company manufacturing Active Pharmaceutical Ingredients, API Intermediates and NDDS/Pellets for the generics market across the world. Set up in 2005, Smilax has emerged a reliable supplier of generic products in the global market today. Set up in 2005, Smilax has emerged a reliable supplier of generic products in the global market today.Set up in 2005, Smilax has emerged a reliable supplier of generic products in the global market today. Smilax manufactures APIs and API Intermediates at its state-of-the-art manufacturing facilities located at Hyderabad, Telangana and Visakhapatnam, Andhra Pradesh, India. Supported by a highly qualified and competent technical team, and endowed with strengths in research and development, Smilax continues to expand its presence in the world of pharmaceuticals.
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1234321-83-5
Sitagliptin Phosphate
SS Pharmaceutical develops and manufactures active pharmaceutical ingredients (APIs), registered pharma i...
SS Pharmaceutical develops and manufactures active pharmaceutical ingredients (APIs), registered pharma intermediates, fine chemicals and pyridine derivatives for the domestic as well as international market. SS Pharma’s research activities extend from the development of active pharmaceuticals to fixed dose formulations for regulated markets. Its manufacturing facilities are state-of-the-art, multipurpose sites that comply with cGMP standards and meet the requirements of the US and EU drug regulatory authorities. SS Pharma is a CGMP, ISO 9001-2008 and ISO 14000:2004 certified company.
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764667-65-4
Sitagliptin Phosphate
SS Pharmaceutical develops and manufactures active pharmaceutical ingredients (APIs), registered pharma i...
SS Pharmaceutical develops and manufactures active pharmaceutical ingredients (APIs), registered pharma intermediates, fine chemicals and pyridine derivatives for the domestic as well as international market. SS Pharma’s research activities extend from the development of active pharmaceuticals to fixed dose formulations for regulated markets. Its manufacturing facilities are state-of-the-art, multipurpose sites that comply with cGMP standards and meet the requirements of the US and EU drug regulatory authorities. SS Pharma is a CGMP, ISO 9001-2008 and ISO 14000:2004 certified company.
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769195-26-8
Sitagliptin Phosphate
SS Pharmaceutical develops and manufactures active pharmaceutical ingredients (APIs), registered pharma i...
SS Pharmaceutical develops and manufactures active pharmaceutical ingredients (APIs), registered pharma intermediates, fine chemicals and pyridine derivatives for the domestic as well as international market. SS Pharma’s research activities extend from the development of active pharmaceuticals to fixed dose formulations for regulated markets. Its manufacturing facilities are state-of-the-art, multipurpose sites that comply with cGMP standards and meet the requirements of the US and EU drug regulatory authorities. SS Pharma is a CGMP, ISO 9001-2008 and ISO 14000:2004 certified company.
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1234321-81-3
Sitagliptin Phosphate
SS Pharmaceutical develops and manufactures active pharmaceutical ingredients (APIs), registered pharma i...
SS Pharmaceutical develops and manufactures active pharmaceutical ingredients (APIs), registered pharma intermediates, fine chemicals and pyridine derivatives for the domestic as well as international market. SS Pharma’s research activities extend from the development of active pharmaceuticals to fixed dose formulations for regulated markets. Its manufacturing facilities are state-of-the-art, multipurpose sites that comply with cGMP standards and meet the requirements of the US and EU drug regulatory authorities. SS Pharma is a CGMP, ISO 9001-2008 and ISO 14000:2004 certified company.
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762240-92-6
Sitagliptin Phosphate
SS Pharmaceutical develops and manufactures active pharmaceutical ingredients (APIs), registered pharma i...
SS Pharmaceutical develops and manufactures active pharmaceutical ingredients (APIs), registered pharma intermediates, fine chemicals and pyridine derivatives for the domestic as well as international market. SS Pharma’s research activities extend from the development of active pharmaceuticals to fixed dose formulations for regulated markets. Its manufacturing facilities are state-of-the-art, multipurpose sites that comply with cGMP standards and meet the requirements of the US and EU drug regulatory authorities. SS Pharma is a CGMP, ISO 9001-2008 and ISO 14000:2004 certified company.
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Sitagliptin Phosphate
Synaptics Labs Private Limited is a young Pharmaceutical Company with a fully integrated and globally spe...
Synaptics Labs Private Limited is a young Pharmaceutical Company with a fully integrated and globally specialized in the development, production and marketing of API’s "Active Pharmaceuticals Ingredients" and its advanced Intermediates, thanks to our focus on satisfying our customers' requirements and supporting the consolidation of a robust infrastructure. The Company promoted by a team of technocrats holding a master’s degree in pharmaceuticals and who have been involved in different Pharmaceutical companies since 24years.
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(±)-4-Fluoro-a-(2-methyl-1-oxopropyl)-g-oxo-N, b-diphe...

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125971-96-2
Atorvastatin
We introduce ourselves as manufacturer of Active Pharmaceutical Ingredients (API) and intermediates with ...
We introduce ourselves as manufacturer of Active Pharmaceutical Ingredients (API) and intermediates with a professional approach that is aimed at finest results. We have etched a respectable place in the industry with proven expertise in manufacturing a wide spectrum of products. Vijayasri today is one of the prominent manufacturers of Active Pharmaceutical Ingredients (API) and intermediates. Our excellent Performance in Contract manufacturing over the years has also earned us the status of a trustable name in the pharmaceutical industry.
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