Company profile for CrossBridge Bio

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About

CrossBridge Bio, founded in 2023 and headquartered in Houston, Texas, pioneers next-generation antibody-drug conjugates (ADCs) for oncology through proprietary stable dual-linker payload technology. The company develops dual-payload ADCs to overcome tumor resistance and heterogeneity, enhancing therapeutic index with precise payload delivery into cancer cells while minimizing off-target effects. Its lead candidate, CBB-120 (TR...
CrossBridge Bio, founded in 2023 and headquartered in Houston, Texas, pioneers next-generation antibody-drug conjugates (ADCs) for oncology through proprietary stable dual-linker payload technology. The company develops dual-payload ADCs to overcome tumor resistance and heterogeneity, enhancing therapeutic index with precise payload delivery into cancer cells while minimizing off-target effects. Its lead candidate, CBB-120 (TROP-2 targeted TOP1i/ATRi), advances toward IND filing in 2026, backed by $15M CPRIT grant and "Best Drug Developer" award at 2025 World ADC Awards.

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Country
U.S.A
Address
Address
2450 Holcombe Blvd., Suite X Houston, TX 77021
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https://www.fiercebiotech.com/biotech/eli-lilly-lassoes-texas-adc-specialist-crossbridge-bio-300m

FIERCE BIOTECH
15 Apr 2026

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