Z Factor Limited is a drug discovery company founded in 2015 to identify and develop therapeutic agents to treat alpha-1-antitrypsin deficiency. The company was created by Index Ventures in partnership with the University of Cambridge.
Alpha-1-antitrypsin deficiency is a genetic disorder that affects 1 in 2,000 people of European descent. The most common disease-causing mutation is the Z-variant. Z alpha-1-antitrypsin is full...
Z Factor Limited is a drug discovery company founded in 2015 to identify and develop therapeutic agents to treat alpha-1-antitrypsin deficiency. The company was created by Index Ventures in partnership with the University of Cambridge.
Alpha-1-antitrypsin deficiency is a genetic disorder that affects 1 in 2,000 people of European descent. The most common disease-causing mutation is the Z-variant. Z alpha-1-antitrypsin is fully functional when secreted, but most of the protein misfolds and accumulates in liver cells as polymers.
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