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XNK Therapeutics
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Hälsovägen 7, Novum 141 57 Huddinge
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XNK01 (evencaleucel) is an autologous NK cell-based drug candidate. It is under phase 2 clinical development in combination with Sarclisa for the treatment of patients with Multiple Myeloma.


Lead Product(s): Evencaleucel,Isatuximab

Therapeutic Area: Oncology Product Name: CellProtect

Highest Development Status: Phase IIProduct Type: Cell and Gene therapy

Partner/Sponsor/Collaborator: Sanofi

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable January 15, 2024

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Under the research agreement, company's autologous natural killer (NK) cell therapy candidate XNK04 will be evaluated in combination with an ADCC competent PD-L1 inhibitor in liver cancer.


Lead Product(s): NK Cell-based Therapy,Antibody

Therapeutic Area: Oncology Product Name: XNK04

Highest Development Status: PreclinicalProduct Type: Cell and Gene therapy

Partner/Sponsor/Collaborator: Undisclosed

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Agreement May 04, 2023

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The autologous NK cell-based product XNK03 is being investigated for the treatment of urothelial cancer, the most common form of bladder cancer. According to the American Cancer Society more than 80,000 new cases of bladder cancer are expected in the US in 2022 alone.


Lead Product(s): XNK03

Therapeutic Area: Oncology Product Name: XNK03

Highest Development Status: PreclinicalProduct Type: Cell and Gene therapy

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable December 15, 2022

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Evencaleucel (XNK01), autologous ex vivo expanded and activated NK cells with potent anti-cancer activity for the treatment of patients with Multiple myeloma.


Lead Product(s): Evencaleucel

Therapeutic Area: Oncology Product Name: XNK01

Highest Development Status: Phase I/ Phase IIProduct Type: Cell and Gene therapy

Partner/Sponsor/Collaborator: Karolinska University Hospital

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable September 26, 2022

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First-in-human Phase I/II clinical trial with CellProtect (ACP-001), in a setting of consolidation treatment following high dose autologous stem cell transplantation in patients newly diagnosed with Multiple myeloma.


Lead Product(s): ACP-001

Therapeutic Area: Oncology Product Name: CellProtect

Highest Development Status: Phase I/ Phase IIProduct Type: Cell and Gene therapy

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable May 02, 2022

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