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TZLS-401 (foralumab) is the only fully human anti-CD3 monoclonal antibody (mAb), binds to the T cell receptor and dampens inflammation by modulating T cell function. It is under phase 2 clinical development for the treatment of Multiple Sclerosis.
Lead Product(s): Foralumab
Therapeutic Area: Neurology Product Name: TZLS-401
Highest Development Status: Phase IIProduct Type: Large molecule
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable January 08, 2024
Details:
TZLS-401 (foralumab) is the only fully human anti-CD3 monoclonal antibody (mAb), binds to the T cell receptor and dampens inflammation by modulating T cell function. It is under phase 2 clinical development for the treatment of Multiple Sclerosis.
Lead Product(s): Foralumab
Therapeutic Area: Neurology Product Name: TZLS-401
Highest Development Status: Phase IIProduct Type: Large molecule
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable December 19, 2023
Details:
TZLS-401 (foralumab) is a CD3 Inhibitor antibody drug administered through intranasal spray for the treatment non-active secondary-progressive multiple sclerosis.
Lead Product(s): Foralumab
Therapeutic Area: Neurology Product Name: TZLS-401
Highest Development Status: Phase IIProduct Type: Large molecule
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable November 30, 2023
Details:
Tiziana’s intranasal TZLS-401 (foralumab), is the only fully human anti-CD3 mAb and has demonstrated a favorable safety profile and clinical response in patients with Multiple Sclerosis.
Lead Product(s): Foralumab
Therapeutic Area: Neurology Product Name: TZLS-401
Highest Development Status: Phase IProduct Type: Large molecule
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable October 18, 2023
Details:
Tiziana’s intranasal TZLS-401 (foralumab), is the only fully human anti-CD3 mAb and has demonstrated a favorable safety profile and clinical response in patients with Multiple Sclerosis.
Lead Product(s): Foralumab
Therapeutic Area: Neurology Product Name: TZLS-401
Highest Development Status: Phase IProduct Type: Large molecule
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable October 13, 2023
Details:
TZLS-401 (foralumab) intranasal, is the only fully human anti-CD3 mAb, which is investigated for the treatment of non-active Secondary Progressive Multiple Sclerosis (na-SPMS) patients.
Lead Product(s): Foralumab
Therapeutic Area: Neurology Product Name: TZLS-401
Highest Development Status: Phase IProduct Type: Large molecule
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable September 26, 2023
Details:
Tiziana’s intranasal TZLS-401 (foralumab), is the only fully human anti-CD3 mAb and has demonstrated a favorable safety profile and clinical response in patients with alzheimer’s disease.
Lead Product(s): Foralumab
Therapeutic Area: Neurology Product Name: TZLS-401
Highest Development Status: IND EnablingProduct Type: Large molecule
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable August 15, 2023
Details:
Tiziana’s intranasal TZLS-401 (foralumab), is the only fully human anti-CD3 mAb and has demonstrated a favorable safety profile and clinical response in patients in studies to date.
Lead Product(s): Foralumab
Therapeutic Area: Neurology Product Name: TZLS-401
Highest Development Status: Phase IProduct Type: Large molecule
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable June 05, 2023
Details:
NI-0401 (foralumab), the only fully human anti-CD3 monoclonal antibody (mAb), binds to the T cell receptor and dampens inflammation by modulating T cell function, thereby suppressing effector features in multiple immune cell subsets.
Lead Product(s): Foralumab
Therapeutic Area: Neurology Product Name: TZLS-401
Highest Development Status: PreclinicalProduct Type: Large molecule
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable April 20, 2023
Details:
NI-0401 (foralumab), the only fully human anti-CD3 monoclonal antibody (mAb), binds to the T cell receptor and dampens inflammation by modulating T cell function, thereby suppressing effector features in multiple immune cell subsets.
Lead Product(s): Foralumab
Therapeutic Area: Endocrinology Product Name: NI-0401
Highest Development Status: PreclinicalProduct Type: Large molecule
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable April 18, 2023
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