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    Company profile for T-knife

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    About

    T-knife is set out to revolutionize the TCR landscape with its unique and proprietary transgenic HuTCR mouse platform to produce fully human TCRs. These TCRs mimic the properties of virus-specific TCRs avoiding immunological tolerance to self tumor antigens in humans. T-knife’s TCRs do not require additional modification but are naturally selected in vivo for an optimal affinity/specificity combination. The Company´s...
    T-knife is set out to revolutionize the TCR landscape with its unique and proprietary transgenic HuTCR mouse platform to produce fully human TCRs. These TCRs mimic the properties of virus-specific TCRs avoiding immunological tolerance to self tumor antigens in humans. T-knife’s TCRs do not require additional modification but are naturally selected in vivo for an optimal affinity/specificity combination. The Company´s lead TCR has entered clinical development in an academic investigator-initiated study in patients with multiple myeloma.

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    T-knifeGermany Flag
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    Germany
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    Robert-Rössle-Str. 10 Berlin, Berlin 13125, DE
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    +49 30 94892432
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    enquiries@pharmacompass.com
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    Website
    https://www.t-knife.com/
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    https://de.linkedin.com/organization-guest/company/t-knife
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    NEWS #PharmaBuzz

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    T-knife Therapeutics Files CTA for TK-6302 T-Cell Therapy
    T-knife Therapeutics Files CTA for TK-6302 T-Cell Therapy

    03 Mar 2026

    // GLOBENEWSWIRE

    https://www.globenewswire.com/news-release/2026/03/03/3248248/0/en/T-knife-Therapeutics-Announces-Authorization-of-Clinical-Trial-Application-for-TK-6302-A-Multi-Armored-CRISPR-based-T-cell-Therapy-for-Solid-Tumors.html

    GLOBENEWSWIRE
    03 Mar 2026
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    T-knife Files Trial Application for Ph 1 ATLAS Trial for TK-6302
    T-knife Files Trial Application for Ph 1 ATLAS Trial for TK-6302

    17 Nov 2025

    // GLOBENEWSWIRE

    https://www.globenewswire.com/news-release/2025/11/17/3189058/0/en/T-knife-Therapeutics-Files-Clinical-Trial-Application-for-Phase-1-ATLAS-Trial-for-TK-6302-a-Supercharged-PRAME-targeted-T-Cell-Receptor-Therapy.html

    GLOBENEWSWIRE
    17 Nov 2025
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    T-Knife Unveils Prame-Targeted TK-6302 Data At SITC Meeting
    T-Knife Unveils Prame-Targeted TK-6302 Data At SITC Meeting

    07 Nov 2025

    // GLOBENEWSWIRE

    https://www.globenewswire.com/news-release/2025/11/07/3183683/0/en/T-knife-Therapeutics-Presents-Preclinical-Data-on-PRAME-Targeted-TK-6302-Highlighting-its-Potential-as-a-Promising-Category-leading-Therapy-at-the-Society-for-Immunotherapy-of-Canc.html

    GLOBENEWSWIRE
    07 Nov 2025
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    T-Knife To Present Four Prame-Targeted TK-6302 Data At SITC
    T-Knife To Present Four Prame-Targeted TK-6302 Data At SITC

    30 Oct 2025

    // GLOBENEWSWIRE

    https://www.globenewswire.com/news-release/2025/10/30/3177301/0/en/T-knife-Therapeutics-Announces-Four-Upcoming-Data-Presentations-on-PRAME-Targeted-TK-6302-at-the-Society-for-Immunotherapy-of-Cancer-SITC-Annual-Meeting.html

    GLOBENEWSWIRE
    30 Oct 2025
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    T-Knife Therapeutics Showcases MyT Platform at ESGCT 2025
    T-Knife Therapeutics Showcases MyT Platform at ESGCT 2025

    07 Oct 2025

    // GLOBENEWSWIRE

    https://www.globenewswire.com/news-release/2025/10/07/3162553/0/en/T-knife-Therapeutics-Presents-Preclinical-Data-Highlighting-the-Transformative-Potential-of-the-MyT-Platform-to-Discover-and-Develop-Next-Generation-TCR-Therapies-to-Treat-Solid-Tu.html

    GLOBENEWSWIRE
    07 Oct 2025
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    T-knife Therapeutics Appoints Christoph Broja to Board
    T-knife Therapeutics Appoints Christoph Broja to Board

    01 Jul 2025

    // GLOBENEWSWIRE

    https://www.globenewswire.com/news-release/2025/07/01/3108260/0/en/T-knife-Therapeutics-Appoints-Christoph-Broja-to-its-Board-of-Directors.html

    GLOBENEWSWIRE
    01 Jul 2025
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