T-knife is set out to revolutionize the TCR landscape with its unique and proprietary transgenic HuTCR mouse platform to produce fully human TCRs. These TCRs mimic the properties of virus-specific TCRs avoiding immunological tolerance to self tumor antigens in humans.
T-knife’s TCRs do not require additional modification but are naturally selected in vivo for an optimal affinity/specificity combination. The Company´s...
T-knife is set out to revolutionize the TCR landscape with its unique and proprietary transgenic HuTCR mouse platform to produce fully human TCRs. These TCRs mimic the properties of virus-specific TCRs avoiding immunological tolerance to self tumor antigens in humans.
T-knife’s TCRs do not require additional modification but are naturally selected in vivo for an optimal affinity/specificity combination. The Company´s lead TCR has entered clinical development in an academic investigator-initiated study in patients with multiple myeloma.
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