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    About

    Step Pharma is developing novel therapeutics that inhibit the enzyme CTP Synthase 1 (CTPS1). Our most advanced programme is STP938 which is being developed as a targeted therapy for T-cell malignancies. Step Pharma was created on the basis of research on genetic immunodeficiencies led by Prof. Alain Fischer at the Imagine Institute (Paris, France) which established the essential role of CTPS1 in T- and B-cell proliferation. ...
    Step Pharma is developing novel therapeutics that inhibit the enzyme CTP Synthase 1 (CTPS1). Our most advanced programme is STP938 which is being developed as a targeted therapy for T-cell malignancies. Step Pharma was created on the basis of research on genetic immunodeficiencies led by Prof. Alain Fischer at the Imagine Institute (Paris, France) which established the essential role of CTPS1 in T- and B-cell proliferation. Step Pharma has developed a series of potent, selective, orally available small molecular weight inhibitors of CTPS1 with STP938 expected to enter clinical development in 2022. The role of CTPS1 in modulating lymphocytes

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    Step PharmaFrance Flag
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    France
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    Forum 2, 218 avenue Marie Curie, Archamps, 74160
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    enquiries@pharmacompass.com
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    https://www.step-ph.com/
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    NEWS #PharmaBuzz

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    Step Pharma Appoints Dr. Karen Smith As Chief Medical Officer
    Step Pharma Appoints Dr. Karen Smith As Chief Medical Officer

    28 Oct 2025

    // GLOBENEWSWIRE

    https://www.globenewswire.com/news-release/2025/10/28/3175309/0/en/Step-Pharma-announces-the-appointment-of-Dr-Karen-Smith-as-Chief-Medical-Officer.html

    GLOBENEWSWIRE
    28 Oct 2025
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    Step Pharma To Present Ctps2-Null Solid Tumors Research
    Step Pharma To Present Ctps2-Null Solid Tumors Research

    21 Oct 2025

    // GLOBENEWSWIRE

    https://www.globenewswire.com/news-release/2025/10/21/3170392/0/en/Step-Pharma-to-spotlight-work-in-CTPS2-null-solid-tumours-at-2025-EORTC-NCI-AACR-International-Conference-on-Molecular-Targets-and-Cancer-Therapeutics.html

    GLOBENEWSWIRE
    21 Oct 2025
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    Step Pharma Completes €38M Series C Funding
    Step Pharma Completes €38M Series C Funding

    15 Oct 2025

    // GLOBENEWSWIRE

    https://www.globenewswire.com/news-release/2025/10/15/3167032/0/en/Step-Pharma-announces-completion-of-38-million-Series-C-financing.html

    GLOBENEWSWIRE
    15 Oct 2025
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    Step Pharma Begins Ph1b Trial of Dencatistat for Thrombocythaemia
    Step Pharma Begins Ph1b Trial of Dencatistat for Thrombocythaemia

    02 Sep 2025

    // GLOBENEWSWIRE

    https://www.globenewswire.com/news-release/2025/09/02/3142569/0/en/Step-Pharma-announces-first-participant-dosed-in-a-phase-1b-clinical-trial-of-dencatistat-for-essential-thrombocythaemia.html

    GLOBENEWSWIRE
    02 Sep 2025
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    Step Pharma to Present Promising Data the Therapeutic Potential Small Molecule
    Step Pharma to Present Promising Data the Therapeutic Potential Small Molecule

    03 Nov 2022

    // GLOBENEWSWIRE

    https://www.globenewswire.com/news-release/2022/11/03/2547732/0/en/Step-Pharma-to-Present-Promising-Data-on-the-Therapeutic-Potential-of-Selective-Small-Molecule-Inhibition-of-CTPS1-at-the-64th-American-Society-of-Hematology-Annual-Meeting.html

    GLOBENEWSWIRE
    03 Nov 2022
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    Step Pharma Announces First Patient Dosed with STP938
    Step Pharma Announces First Patient Dosed with STP938

    24 Oct 2022

    // GLOBENEWSWIRE

    https://www.globenewswire.com/news-release/2022/10/24/2539648/0/en/Step-Pharma-Announces-First-Patient-Dosed-with-STP938-the-World-s-Most-Advanced-CTPS1-Inhibitor-in-a-Phase-1-2-Trial-for-T-cell-and-B-cell-lymphomas.html

    GLOBENEWSWIRE
    24 Oct 2022
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