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Details:

OT-101, is a first-in-class anti-TGF-β2 RNA therapeutic that exhibited single agent activity in some relapsed/refractory cancer (metastatic pancreatic cancer) patients. TGF-β2 has been implicated as a key contributor to the immunosuppressive landscape of the TME in HGG.


Lead Product(s): Trabedersen,Fluorouracil,Irinotecan Hydrochloride

Therapeutic Area: Oncology Product Name: OT-101

Highest Development Status: Phase II/ Phase IIIProduct Type: Large molecule

Partner/Sponsor/Collaborator: Cromos Pharma

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable August 23, 2023

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