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    Company profile for Rgenta Therapeutics

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    Rgenta Therapeutics is developing a pipeline of oral, small-molecule RNA-targeting medicines with an initial focus on oncology and neurological disorders. Our proprietary platform mines the massive genomics data to identify targetable RNA processing events and design small-molecule glues to modulate the interactions among the spliceosome, regulatory proteins, and RNAs. Our lead programs and unique approach are unlocking the t...
    Rgenta Therapeutics is developing a pipeline of oral, small-molecule RNA-targeting medicines with an initial focus on oncology and neurological disorders. Our proprietary platform mines the massive genomics data to identify targetable RNA processing events and design small-molecule glues to modulate the interactions among the spliceosome, regulatory proteins, and RNAs. Our lead programs and unique approach are unlocking the therapeutic potential of historically undruggable targets in human diseases.

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    Rgenta TherapeuticsUnited_States_of_America Flag
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    300 TradeCenter Suite 6600, Woburn, MA 01801
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    enquiries@pharmacompass.com
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    https://www.rgentatx.com/
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    NEWS #PharmaBuzz

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    Rgenta Therapeutics Presents Preclinical Data RGT-0474060
    Rgenta Therapeutics Presents Preclinical Data RGT-0474060

    25 Feb 2026

    // GLOBENEWSWIRE

    https://www.globenewswire.com/news-release/2026/02/25/3244536/0/en/Rgenta-Therapeutics-Presents-Preclinical-Data-Unveiling-its-New-Drug-Candidate-RGT-0474060-as-a-Promising-Oral-PMS1-Inhibitor-for-the-Treatment-of-Huntington-s-Disease.html

    GLOBENEWSWIRE
    25 Feb 2026
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    Rgenta Pharma Granted FDA Orphan Drug Status for RGT-61159
    Rgenta Pharma Granted FDA Orphan Drug Status for RGT-61159

    17 Sep 2025

    // GLOBENEWSWIRE

    https://www.globenewswire.com/news-release/2025/09/17/3151594/0/en/Rgenta-Therapeutics-Receives-Orphan-Drug-Designation-from-the-U-S-FDA-for-RGT-61159-for-the-Treatment-of-Adenoid-Cystic-Carcinoma-ACC.html

    GLOBENEWSWIRE
    17 Sep 2025
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    Rgenta Therapeutics Presents Preclinical Data from RGT-61159
    Rgenta Therapeutics Presents Preclinical Data from RGT-61159

    12 Jun 2025

    // GLOBENEWSWIRE

    https://www.globenewswire.com/news-release/2025/06/12/3098260/0/en/Rgenta-Therapeutics-Presents-Preclinical-Data-from-Lead-Program-RGT-61159-a-Potent-and-Selective-Small-Molecule-Inhibitor-of-MYB-RNA-Supporting-its-Application-in-the-Treatment-of-.html

    GLOBENEWSWIRE
    12 Jun 2025
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    Rgenta Therapeutics Presents Data on RSwitch Technology
    Rgenta Therapeutics Presents Data on RSwitch Technology

    13 May 2025

    // PR NEWSWIRE

    https://www.prnewswire.com/news-releases/rgenta-therapeutics-presents-data-from-proprietary-rswitch-technology-demonstrating-versatile-tunable-transgene-expression-in-aav-delivered-gene-therapies-with-orally-administered-small-molecules-rdrugs-302454498.html

    PR NEWSWIRE
    13 May 2025
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    Rgenta Announces First Patients Dosed In Ph1a/b in Adenoid Carcinoma
    Rgenta Announces First Patients Dosed In Ph1a/b in Adenoid Carcinoma

    08 Oct 2024

    // PR NEWSWIRE

    https://www.prnewswire.com/news-releases/rgenta-therapeutics-announces-first-patients-dosed-in-phase-1ab-clinical-trial-of-rgt-61159-an-oral-small-molecule-targeting-myb-in-adenoid-cystic-carcinoma-acc-and-colorectal-cancer-crc-302269345.html

    PR NEWSWIRE
    08 Oct 2024
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    FDA Clears Rgenta's IND For RGT-61159 In ACC And Colorectal Cancer
    FDA Clears Rgenta's IND For RGT-61159 In ACC And Colorectal Cancer

    10 Jul 2024

    // PR NEWSWIRE

    https://www.prnewswire.com/news-releases/rgenta-therapeutics-announces-fda-clearance-of-ind-application-for-rgt-61159-an-oral-small-molecule-rna-modulator-designed-to-halt-disease-driver-myb-production-in-adenoid-cystic-carcinoma-acc-and-colorectal-cancer-crc-302192676.html

    PR NEWSWIRE
    10 Jul 2024
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