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PKX-001 is the designation given to the lead drug product molecule of the Antiaging Glycopeptide family. Islet cell transplants are well recognized as a viable and effective treatment for Type-1 diabetes.
Lead Product(s): Antiaging Glycopeptide
Therapeutic Area: Endocrinology Product Name: PKX-001
Highest Development Status: Phase IProduct Type: Peptide
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable July 20, 2022
Details:
Selected two formulations of AAGP (Anti-Aging Glycopeptide ) product to be advanced into preclinical efficacy testing for the topical treatment of dry eye disease and ocular inflammation.
Lead Product(s): Anti-Aging Glycopeptide
Therapeutic Area: Ophthalmology Product Name: AAGP
Highest Development Status: PreclinicalProduct Type: Peptide
Partner/Sponsor/Collaborator: Catalent Pharma Solutions
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable November 23, 2021
Details:
The ProtoKinetix-IQVIA collaboration will aim to accelerate the clinical development and regulatory progress of PKX-001. The collaboration is expected to drive directed clinical development as PKX-001 enters Phase 1 testing for the above conditions.
Lead Product(s): Antiaging Glycopeptide
Therapeutic Area: Ophthalmology Product Name: PKX-001
Highest Development Status: PreclinicalProduct Type: Peptide
Recipient: IQVIA
Deal Size: Undisclosed Upfront Cash: Undisclosed
Deal Type: Partnership May 12, 2021
Details:
PKTX-001 has shown to significantly improve cell survival and integration into host tissue and will be a valuable asset in the field of regenerative medicine in the future.
Lead Product(s): Pegloticase
Therapeutic Area: Ophthalmology Product Name: PKTX-001
Highest Development Status: PreclinicalProduct Type: Cell and Gene therapy
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable April 07, 2021
Details:
This phase of the clinical trials, based on safety data received from the initial studies in Phase 1, demonstrated the safety of the molecule and are now approved to adjust the protocols for optimal efficacy.
Lead Product(s): Antiaging Glycopeptide
Therapeutic Area: Endocrinology Product Name: PKX-001
Highest Development Status: Phase IProduct Type: Peptide
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable August 27, 2020
Details:
Upon approval from Health Canada and upon final approval by the University of Alberta ethics committee, the Company will be immediately delivering over 75-grams of the PKX-001 to the University to accommodate the ongoing clinical trial.
Lead Product(s): Antiaging Glycopeptide
Therapeutic Area: Endocrinology Product Name: PKX-001
Highest Development Status: Phase IProduct Type: Peptide
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable July 13, 2020
Details:
The PKX-001 study will treat islet cells prior to transplantation into human test subjects. The clinical trials primary objective is the establishment of patient safety.
Lead Product(s): Antiaging Glycopeptide
Therapeutic Area: Endocrinology Product Name: Undisclosed
Highest Development Status: Phase IProduct Type: Peptide
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable March 24, 2020
Details:
GMP AAGP® PKX-001 will be sent to the University of Alberta for use in the continuation of the Phase-1 first-in-human clinical trials of PKX-001 for the treatment of Type-1 diabetes.
Lead Product(s): PKX-001
Therapeutic Area: Endocrinology Product Name: Undisclosed
Highest Development Status: Phase IProduct Type: Peptide
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable January 24, 2020
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