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Find Clinical Drug Pipeline Developments & Deals by ProtoKinetix
PKX-001 is the designation given to the lead drug product molecule of the Antiaging Glycopeptide family. Islet cell transplants are well recognized as a viable and effective treatment for Type-1 diabetes.
Selected two formulations of AAGP (Anti-Aging Glycopeptide ) product to be advanced into preclinical efficacy testing for the topical treatment of dry eye disease and ocular inflammation.
The ProtoKinetix-IQVIA collaboration will aim to accelerate the clinical development and regulatory progress of PKX-001. The collaboration is expected to drive directed clinical development as PKX-001 enters Phase 1 testing for the above conditions.
PKTX-001 has shown to significantly improve cell survival and integration into host tissue and will be a valuable asset in the field of regenerative medicine in the future.
This phase of the clinical trials, based on safety data received from the initial studies in Phase 1, demonstrated the safety of the molecule and are now approved to adjust the protocols for optimal efficacy.
Upon approval from Health Canada and upon final approval by the University of Alberta ethics committee, the Company will be immediately delivering over 75-grams of the PKX-001 to the University to accommodate the ongoing clinical trial.
The PKX-001 study will treat islet cells prior to transplantation into human test subjects. The clinical trials primary objective is the establishment of patient safety.
GMP AAGP® PKX-001 will be sent to the University of Alberta for use in the continuation of the Phase-1 first-in-human clinical trials of PKX-001 for the treatment of Type-1 diabetes.