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Details:
OR502 a novel, humanized anti-leukocyte immunoglobulin like receptor B2 (LILRB2) antibody. It is being evaluated for the treatment of advanced solid tumors.
Lead Product(s): OR502,Cemiplimab
Therapeutic Area: Oncology Product Name: OR502
Highest Development Status: Phase I/ Phase IIProduct Type: Large molecule
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable November 29, 2023
Details:
The CPRIT award will support the advancement of OR502, a best-in-class anti-LILRB2 antibody that rescues innate and adaptive immune responses from LILRB2-mediated immune suppression, poised to move to IND and clinical studies.
Lead Product(s): OR502
Therapeutic Area: Oncology Product Name: OR502
Highest Development Status: IND EnablingProduct Type: Large molecule
Partner/Sponsor/Collaborator: CPRIT
Deal Size: $13.0 million Upfront Cash: Undisclosed
Deal Type: Funding May 18, 2023
Details:
The investment will support the advancement of OR502, a best-in-class anti-LILRB2 antibody that rescues innate and adaptive immune responses from LILRB2-mediated immune suppression, poised to move to IND and clinical studies.
Lead Product(s): OR502
Therapeutic Area: Oncology Product Name: OR502
Highest Development Status: IND EnablingProduct Type: Large molecule
Partner/Sponsor/Collaborator: RiverVest Venture Partners
Deal Size: $14.0 million Upfront Cash: Undisclosed
Deal Type: Financing May 18, 2023
Details:
The supply agreement will support the evaluation of Libtayo in combination with OR2805, a fully human monoclonal antibody identified from an elite cancer responder using OncoResponse’s proprietary B-cell discovery platform.
Lead Product(s): OR2805,Cemiplimab
Therapeutic Area: Oncology Product Name: OR2805
Highest Development Status: PreclinicalProduct Type: Large molecule
Partner/Sponsor/Collaborator: Regeneron Pharmaceuticals
Deal Size: Undisclosed Upfront Cash: Undisclosed
Deal Type: Agreement September 07, 2022