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The proceeds will advance the development activities of the Company's assets, with a particular focus on progressing towards the clinical phase, including ExoPTEN, targeted at acute Spinal Cord Injury is being developed using ExoTherapy Technology and Platform.


Lead Product(s): ExoPTEN

Therapeutic Area: Trauma (Emergency, Injury, Surgery) Product Name: ExoPTEN

Highest Development Status: PreclinicalProduct Type: Large molecule

Partner/Sponsor/Collaborator: Undisclosed

Deal Size: $2.9 million Upfront Cash: Undisclosed

Deal Type: Private Placement March 27, 2024

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Vivox will provide Contract Research Organization services to NurExone, as a prerequisite to commencing human trials representing a significant step towards filing an IND application in the US for NurExone’s ExoPTEN exosome-based therapy for spinal cord injury.


Lead Product(s): ExoPTEN

Therapeutic Area: Trauma (Emergency, Injury, Surgery) Product Name: ExoPTEN

Highest Development Status: PreclinicalProduct Type: Large molecule

Recipient: Vivox

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Agreement March 22, 2024

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ExoPTEN comprises exosomes loaded with small interfering RNA (siRNA) that inhibits the production of the PTEN protein. It is being evaluated in preclinical studies for the treatment of acute spinal cord injury.


Lead Product(s): ExoPTEN

Therapeutic Area: Trauma (Emergency, Injury, Surgery) Product Name: ExoPTEN

Highest Development Status: PreclinicalProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable February 02, 2024

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The collaboration aims at combining Inteligex’s more than twenty years of experience in cell-based therapies and NurExone’s innovative exosome platform to develop therapies for patients with chronic spinal cord injuries.


Lead Product(s): Exosome-based Therapy

Therapeutic Area: Trauma (Emergency, Injury, Surgery) Product Name: Undisclosed

Highest Development Status: Discovery PlatformProduct Type: Cell and Gene therapy

Partner/Sponsor/Collaborator: Inteligex

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration January 17, 2024

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Details:

The proceeds will advance the development activities of the Company's assets, with a particular focus on progressing towards the clinical phase, including ExoPTEN, targeted at acute Spinal Cord Injury is being developed using ExoTherapy Technology and Platform.


Lead Product(s): ExoPTEN

Therapeutic Area: Trauma (Emergency, Injury, Surgery) Product Name: ExoPTEN

Highest Development Status: PreclinicalProduct Type: Large molecule

Partner/Sponsor/Collaborator: Undisclosed

Deal Size: $1.4 million Upfront Cash: Undisclosed

Deal Type: Private Placement January 05, 2024

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ExoPTEN is being developed to be a minimally invasive ExoTherapy for spinal cord injuries (SCI), yielding neuron regeneration and rewiring in traumatically damaged spinal cord.


Lead Product(s): Biologically-guided Exosome Therapy

Therapeutic Area: Trauma (Emergency, Injury, Surgery) Product Name: ExoTherapy

Highest Development Status: PreclinicalProduct Type: Cell and Gene therapy

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable October 30, 2023

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NurExone is in the process of developing the ExoPTEN product specifically for acute spinal cord injuries. This collaborative effort opens the possibility for the company to expand its focus to chronic spine injuries by developing Exo Therpies.


Lead Product(s): ExoTherapy

Therapeutic Area: Trauma (Emergency, Injury, Surgery) Product Name: Undisclosed

Highest Development Status: PreclinicalProduct Type: Cell and Gene therapy

Partner/Sponsor/Collaborator: Israeli Shekels

Deal Size: $0.2 million Upfront Cash: Undisclosed

Deal Type: Funding October 11, 2023

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Details:

ExoPTEN is being developed to be a minimally invasive ExoTherapy for spinal cord injuries (SCI), yielding neuron regeneration and rewiring in traumatically damaged spinal cord.


Lead Product(s): Exosome

Therapeutic Area: Trauma (Emergency, Injury, Surgery) Product Name: ExoPTEN

Highest Development Status: IND EnablingProduct Type: Cell and Gene therapy

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable September 13, 2023

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Details:

ExoPTEN is being developed to be a minimally invasive ExoTherapy for spinal cord injuries (SCI), yielding neuron regeneration and rewiring in traumatically damaged spinal cord.


Lead Product(s): Exosome

Therapeutic Area: Trauma (Emergency, Injury, Surgery) Product Name: ExoPTEN

Highest Development Status: PreclinicalProduct Type: Cell and Gene therapy

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable June 22, 2023

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Details:

ExoPTEN is being developed to be a minimally invasive ExoTherapy for spinal cord injuries (SCI), yielding neuron regeneration and rewiring in traumatically damaged spinal cord.


Lead Product(s): Biologically-guided Exosome Therapy

Therapeutic Area: Trauma (Emergency, Injury, Surgery) Product Name: ExoTherapy

Highest Development Status: PreclinicalProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable May 16, 2023

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