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    MEBIAS DISCOVERY

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    MEBIAS holds a game-changing platform to discover next generation, pathway-selective GPCR drugs devoid of on-target side effects once thought to be unavoidable. G-protein Coupled Receptor (GPCR) therapeutics comprise ~30% of current prescribed drugs. By developing pathway-selective/biased drugs within well-understood mechanisms, the significant on-target adverse effects can be alleviated. Cell-based assays alone are inadequate...
    MEBIAS holds a game-changing platform to discover next generation, pathway-selective GPCR drugs devoid of on-target side effects once thought to be unavoidable. G-protein Coupled Receptor (GPCR) therapeutics comprise ~30% of current prescribed drugs. By developing pathway-selective/biased drugs within well-understood mechanisms, the significant on-target adverse effects can be alleviated. Cell-based assays alone are inadequate to identify biased drugs. Mebias’ understanding of protein dynamics of GPCRs offers a unique advantage.
    veranova-m-2024-04-22

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    Mebias Discovery
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    3001 Market Street, Suite 140, Philadelphia, PA 19104
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    https://mebiasdiscovery.com/
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    veranova-m-2024-04-22

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