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Details:
The research collaboration will leverage Imagine Pharma’s Type 1 Diabetes Activated Islet Progenitor Cells (T1D AIPCs) and LyGenesis’ allogeneic cell therapy platform to develop therapies for type 1 diabetes.
Lead Product(s): Undisclosed
Therapeutic Area: Endocrinology Product Name: Undisclosed
Highest Development Status: PreclinicalProduct Type: Cell and Gene therapy
Partner/Sponsor/Collaborator: Imagine Pharma
Deal Size: Undisclosed Upfront Cash: Undisclosed
Deal Type: Collaboration April 12, 2023
Details:
AgeX has two preclinical cell therapy programs: AGEX-VASC1 (vascular progenitor cells) for tissue ischemia and AGEX-BAT1 (brown fat cells) for Type II diabetes.
Lead Product(s): AGEX-VASC1
Therapeutic Area: Cardiology/Vascular Diseases Product Name: AGEX-VASC1
Highest Development Status: PreclinicalProduct Type: Cell and Gene therapy
Recipient: AgeX Therapeutics
Deal Size: Undisclosed Upfront Cash: Undisclosed
Deal Type: Termination July 23, 2021
Details:
LYG-LIV0001 is a regenerative mobile remedy comprising allogeneic hepatocytes suspended in a buffered cell preservation resolution which are transplanted into periduodenal lymph nodes.
Lead Product(s): LYG-LIV0001
Therapeutic Area: Hepatology (Liver, Pancreatic, Gall Bladder) Product Name: LYG-LIV0001
Highest Development Status: Phase IIProduct Type: Cell and Gene therapy
Partner/Sponsor/Collaborator: AgeX Therapeutics
Deal Size: Undisclosed Upfront Cash: Undisclosed
Deal Type: Merger March 02, 2021
Details:
Proceeds will be used to fund LyGenesis’s Phase 2a clinical trial with a first patient in targeted for early 2021, also to push forward on their other cell therapies using lymph nodes as bioreactors to regrow functioning organs.
Lead Product(s): LYG-LIV0001
Therapeutic Area: Hepatology (Liver, Pancreatic, Gall Bladder) Product Name: LYG-LIV0001
Highest Development Status: Phase IIProduct Type: Cell and Gene therapy
Partner/Sponsor/Collaborator: Juvenescence
Deal Size: $11.0 million Upfront Cash: Undisclosed
Deal Type: Financing December 30, 2020
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