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177Lu-OncoFAP-23 exhibits, in pre-clinical models, a very high and selective tumor uptake and with a significantly extended residence time at the site of disease, compared to other 177Lu-FAP-ligands.


Lead Product(s): 177Lu-OncoFAP-23

Therapeutic Area: Oncology Product Name: 177Lu-OncoFAP-23

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Philochem

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration December 13, 2022

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177Lu-FAP-2286 consists of two functional elements; a targeting peptide that binds to FAP and a site that can be used to attach medical radioisotopes, such as lutetium-177 for therapeutic use, or gallium-68 for imaging use.


Lead Product(s): 177Lu-FAP-2286

Therapeutic Area: Oncology Product Name: 177Lu-FAP-2286

Highest Development Status: Phase I/ Phase IIProduct Type: Peptide

Recipient: Clovis Oncology

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Agreement September 21, 2022

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177Lu n.c.a (No-carrier-added Lutetium-177) is a very versatile isotope, and worldwide numerous clinical trials are being held, studying the effects of this isotope, used radiometal for targeted radiotherapy.


Lead Product(s): No-Carrier-Added Lutetium-177

Therapeutic Area: Oncology Product Name: n.c.a 177 Lu

Highest Development Status: UndisclosedProduct Type: Small molecule

Partner/Sponsor/Collaborator: CPDC Centre for Probe Development and Commercialization

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable June 09, 2022

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Seibersdorf Labor, a GMP Contract manufacturing of radiopharmaceuticals, a global leader in the development, production, and commercialization of radiopharmaceuticals, will produce 177Lu n.c.a in collaboration with Isotopia Molecular Imaging for distribution in Europe.


Lead Product(s): No-carrier-added Lutetium-177

Therapeutic Area: Oncology Product Name: 177Lu n.c.a

Highest Development Status: UndisclosedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Seibersdorf Labor GmbH

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration October 18, 2021

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