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    Company profile for HepaRegeniX

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    About

    HepaRegeniX develops a new and unique therapeutic concept for the treatment of liver diseases. The laboratory of Prof. Lars Zender identified Mitogen-Activated Protein (MAP) Kinase Kinase 4 (MKK4) as a key regulator of liver regeneration. Suppression of MKK4 gene expression by small RNA molecules unlocks the regenerative capacity of hepatocytes even in severely diseased livers. These findings paved the way for the unique an...
    HepaRegeniX develops a new and unique therapeutic concept for the treatment of liver diseases. The laboratory of Prof. Lars Zender identified Mitogen-Activated Protein (MAP) Kinase Kinase 4 (MKK4) as a key regulator of liver regeneration. Suppression of MKK4 gene expression by small RNA molecules unlocks the regenerative capacity of hepatocytes even in severely diseased livers. These findings paved the way for the unique and promising therapeutic concept to develop small molecule MKK4 inhibitors to treat acute and chronic liver diseases. In particular, following thorough characterization of the underlying molecular mechanism of drug.

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    CONTACT DETAILS

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    HepaRegeniXGermany Flag
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    Country
    Germany
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    Address
    Alfred-Mendler-Weg 25/1, 89075 Ulm
    Telephone
    Telephone
    +49 (0)7071 6396731
    Client Email
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    enquiries@pharmacompass.com
    Client Website
    Website
    https://www.heparegenix.com/
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    Twitter

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    NEWS #PharmaBuzz

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    HepaRegeniX Completes Phase Ib HRX-215 Liver Study
    HepaRegeniX Completes Phase Ib HRX-215 Liver Study

    11 Feb 2026

    // GLOBENEWSWIRE

    https://www.globenewswire.com/news-release/2026/02/11/3236026/0/en/HepaRegeniX-Completes-Phase-Ib-Study-of-HRX-215-to-Enhance-Liver-Regeneration-in-Patients-Undergoing-Minor-Liver-Resection.html

    GLOBENEWSWIRE
    11 Feb 2026
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    HepaRegeniX Doses First Patient in Phase Ib Trial with HRX-215
    HepaRegeniX Doses First Patient in Phase Ib Trial with HRX-215

    10 Jun 2025

    // GLOBENEWSWIRE

    https://www.globenewswire.com/news-release/2025/06/10/3096394/0/en/HepaRegeniX-Doses-First-Patient-in-Phase-Ib-Trial-with-Small-Molecule-Inhibitor-HRX-215-to-Promote-Liver-Regeneration.html

    GLOBENEWSWIRE
    10 Jun 2025
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    HepaRegeniX Founder Presents HRX-215 Data at EASL Congress 2025
    HepaRegeniX Founder Presents HRX-215 Data at EASL Congress 2025

    08 May 2025

    // GLOBENEWSWIRE

    https://www.globenewswire.com/news-release/2025/05/08/3077246/0/en/HepaRegeniX-Scientific-Founder-Covers-HRX-215-Development-and-Clincial-Data-in-Plenary-at-the-European-Association-for-the-Study-of-the-Liver-Congress-2025.html

    GLOBENEWSWIRE
    08 May 2025
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    HepaRegeniX secures €21.5M for HRX-215 liver regeneration
    HepaRegeniX secures €21.5M for HRX-215 liver regeneration

    15 Apr 2025

    // GLOBENEWSWIRE

    https://www.globenewswire.com/news-release/2025/04/15/3061487/0/en/HepaRegeniX-completes-21-5-million-financing-to-support-clinical-advancement-of-HRX-215-for-liver-regeneration.html

    GLOBENEWSWIRE
    15 Apr 2025
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    HepaRegeniX Raises €15M For HRX-215 Liver Regeneration Development
    HepaRegeniX Raises €15M For HRX-215 Liver Regeneration Development

    10 Jul 2024

    // GLOBENEWSWIRE

    https://www.globenewswire.com/news-release/2024/07/10/2910869/0/en/HepaRegeniX-raises-15-million-Series-C-round-to-advance-clinical-development-of-HRX-215-for-liver-regeneration.html

    GLOBENEWSWIRE
    10 Jul 2024
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    HepaRegeniX publishes data for its first-in-class MKK4 inhibitor HRX-215
    HepaRegeniX publishes data for its first-in-class MKK4 inhibitor HRX-215

    14 Mar 2024

    // GLOBENEWSWIRE

    https://www.globenewswire.com//news-release/2024/03/14/2846504/0/en/HepaRegeniX-publishes-data-for-its-first-in-class-MKK4-inhibitor-HRX-215-for-the-treatment-of-acute-and-chronic-liver-diseases-in-Cell.html

    GLOBENEWSWIRE
    14 Mar 2024
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