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Under the agreement, Helocyte gains patent rights to use CMV-MVA Triplex, a cytomegalovirus vaccine, in combination with cytomegalovirus-specific, Anti-HIV CAR T Cells for the treatment of adults living with HIV.


Lead Product(s): CMV-MVA Triplex

Therapeutic Area: Infections and Infectious Diseases Product Name: CMV-MVA Triplex

Highest Development Status: Phase IIProduct Type: Vaccine

Recipient: City of Hope

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Licensing Agreement October 16, 2023

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The funding will be used for clinical studies of Triplex, a cytomegalovirus (CMV), universal (non-HLA-restricted) recombinant Modified Vaccinia Ankara viral vector vaccine, being developed by Helocyte and City of Hope.


Lead Product(s): CMV-MVA Triplex Vaccine

Therapeutic Area: Infections and Infectious Diseases Product Name: Triplex

Highest Development Status: Phase IIProduct Type: Vaccine

Partner/Sponsor/Collaborator: National Cancer Institute

Deal Size: $3.2 million Upfront Cash: Undisclosed

Deal Type: Funding June 15, 2023

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Triplex is a universal (non-HLA-restricted) recombinant Modified Vaccinia Ankara viral vector vaccine engineered to induce a robust and durable CMV-specific T cell response to three immuno-dominant proteins.


Lead Product(s): CMV-modified Vaccinia Ankara Vaccine

Therapeutic Area: Infections and Infectious Diseases Product Name: Triplex

Highest Development Status: Phase IIProduct Type: Vaccine

Partner/Sponsor/Collaborator: National Institute of Allergy and Infectious Diseases

Deal Size: $20.0 million Upfront Cash: Undisclosed

Deal Type: Funding August 11, 2022

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