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Helmholtz Zentrum München
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Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) Ingolstaedter Landstrasse 1 D-85764 Neuherberg
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ITM-31 is a carbonic anhydrase (CA) XII-specific antibody Fab fragment, which is currently being evaluated for the treatment of glioblastoma.


Lead Product(s): Lu-177 labeled 6A10-Fab-fragments

Therapeutic Area: Oncology Product Name: ITM-31

Highest Development Status: Phase IProduct Type: Large molecule

Recipient: Isotope Technologies Munich

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable April 23, 2024

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Under the agreement, Medigene accelerates the expansion of its end-to-end platform of multiple, combinable, exclusive and proprietary technologies with the potential to create best-in-class T cell receptor engineered T cell (TCR-T) therapies for patients with solid tumors.


Lead Product(s): TCR-T-based Therapy

Therapeutic Area: Oncology Product Name: Undisclosed

Highest Development Status: DiscoveryProduct Type: Cell and Gene therapy

Partner/Sponsor/Collaborator: Medigene

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Licensing Agreement May 02, 2023

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Under the terms of the license agreement, ITM will hold exclusive rights to the compound ITM-31 as well as the rights to related patents and know-how for the manufacturing and use of ITM-31.


Lead Product(s): ITM-31

Therapeutic Area: Oncology Product Name: ITM-31

Highest Development Status: PreclinicalProduct Type: Small molecule

Partner/Sponsor/Collaborator: Isotope Technologies Munich

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Licensing Agreement October 19, 2022

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