Polpharma European CDMO Partner & API Manufacturer since 1951 Polpharma European CDMO Partner & API Manufacturer since 1951

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LIB003 (lerodalcibep) is a potential best in class, novel, small binding protein, third-generation PCSK9 inhibitor, which is being evaluated for the treatment and prevention of cardiovascular disease.


Lead Product(s): Lerodalcibep

Therapeutic Area: Cardiology/Vascular Diseases Product Name: LIB003

Highest Development Status: Phase IIIProduct Type: Large molecule

Recipient: LIB Therapeutics

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 19, 2024

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Under the terms of the agreement, LIB has granted Hasten the exclusive rights to develop and commercialize LIB003 (lerodalcibep), a next-generation, PCSK9 inhibitor, for patients at very high and high-risk of cardiovascular disease, in Greater China.


Lead Product(s): Lerodalcibep

Therapeutic Area: Genetic Disease Product Name: LIB003

Highest Development Status: Phase IIIProduct Type: Large molecule

Recipient: LIB Therapeutics

Deal Size: $325.0 million Upfront Cash: $20.0 million

Deal Type: Licensing Agreement September 12, 2023

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The proceeds will fund the future acquisitions and business development of five cardiovascular and metabolic products, including Ebrantil®, Edarbi®, Blopress®, Basen®, and Actos®. Edarbi (azilsartan medoxomil) is an angiotensin II receptor blocker, used to treat hypertension.


Lead Product(s): Azilsartan

Therapeutic Area: Cardiology/Vascular Diseases Product Name: Edarbi

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: CBC Group

Deal Size: $315.0 million Upfront Cash: Undisclosed

Deal Type: Financing April 20, 2023

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