[{"orgOrder":0,"company":"Hasten Biopharmaceutic","sponsor":"F. Hoffmann-La Roche","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"SWITZERLAND","productType":"Antibiotic","year":"2023","type":"Acquisition","leadProduct":"Ceftriaxone","moa":"||Cell wall peptidoglycan synthesis","graph1":"Infections and Infectious Diseases","graph2":"Approved FDF","graph3":"Hasten Biopharmaceutic","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Intravenous Injection","sponsorNew":"Hasten Biopharmaceutic \/ Hasten Biopharmaceutic","highestDevelopmentStatusID":"15","companyTruncated":"Hasten Biopharmaceutic \/ Hasten Biopharmaceutic"},{"orgOrder":0,"company":"Hasten Biopharmaceutic","sponsor":"CBC Group","pharmaFlowCategory":"D","therapeuticArea":"Cardiology\/Vascular Diseases","country":"CHINA","productType":"Other Small Molecule","year":"2023","type":"Financing","leadProduct":"Azilsartan","moa":"||Angiotensin II receptor","graph1":"Cardiology\/Vascular Diseases","graph2":"Approved FDF","graph3":"Hasten Biopharmaceutic","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Hasten Biopharmaceutic \/ CBC Group","highestDevelopmentStatusID":"15","companyTruncated":"Hasten Biopharmaceutic \/ CBC Group"},{"orgOrder":0,"company":"Hasten Biopharmaceutic","sponsor":"Takeda Pharmaceutical","pharmaFlowCategory":"D","therapeuticArea":"Cardiology\/Vascular Diseases","country":"JAPAN","productType":"Other Small Molecule","year":"2022","type":"Acquisition","leadProduct":"Azilsartan","moa":"||Angiotensin II receptor","graph1":"Cardiology\/Vascular Diseases","graph2":"Approved FDF","graph3":"Hasten Biopharmaceutic","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Hasten Biopharmaceutic \/ Hasten Biopharmaceutic","highestDevelopmentStatusID":"15","companyTruncated":"Hasten Biopharmaceutic \/ Hasten Biopharmaceutic"},{"orgOrder":0,"company":"Hasten Biopharmaceutic","sponsor":"Celltrion","pharmaFlowCategory":"D","therapeuticArea":"Cardiology\/Vascular Diseases","country":"SOUTH KOREA","productType":"Other Small Molecule","year":"2024","type":"Acquisition","leadProduct":"Azilsartan","moa":"||Angiotensin II receptor","graph1":"Cardiology\/Vascular Diseases","graph2":"Approved FDF","graph3":"Hasten Biopharmaceutic","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Hasten Biopharmaceutic \/ Hasten Biopharmaceutic","highestDevelopmentStatusID":"15","companyTruncated":"Hasten Biopharmaceutic \/ Hasten Biopharmaceutic"},{"orgOrder":0,"company":"Hasten Biopharmaceutic","sponsor":"Celltrion","pharmaFlowCategory":"D","therapeuticArea":"Cardiology\/Vascular Diseases","country":"SOUTH KOREA","productType":"Other Small Molecule","year":"2024","type":"Acquisition","leadProduct":"Azilsartan","moa":"||Angiotensin II receptor","graph1":"Cardiology\/Vascular Diseases","graph2":"Approved FDF","graph3":"Hasten Biopharmaceutic","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Hasten Biopharmaceutic \/ Hasten Biopharmaceutic","highestDevelopmentStatusID":"15","companyTruncated":"Hasten Biopharmaceutic \/ Hasten Biopharmaceutic"},{"orgOrder":0,"company":"Hasten Biopharmaceutic","sponsor":"LIB Therapeutics","pharmaFlowCategory":"DU","therapeuticArea":"Cardiology\/Vascular Diseases","country":"U.S.A","productType":"Protein","year":"2024","type":"Inapplicable","leadProduct":"Inapplicable","moa":"||PCSK9","graph1":"Cardiology\/Vascular Diseases","graph2":"Phase III","graph3":"Hasten Biopharmaceutic","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Subcutaneous Injection","sponsorNew":"Hasten Biopharmaceutic \/ Hasten Biopharmaceutic","highestDevelopmentStatusID":"10","companyTruncated":"Hasten Biopharmaceutic \/ Hasten Biopharmaceutic"},{"orgOrder":0,"company":"Hasten Biopharmaceutic","sponsor":"LIB Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Cardiology\/Vascular Diseases","country":"U.S.A","productType":"Protein","year":"2023","type":"Licensing Agreement","leadProduct":"Inapplicable","moa":"||PCSK9","graph1":"Cardiology\/Vascular Diseases","graph2":"Phase III","graph3":"Hasten Biopharmaceutic","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Subcutaneous Injection","sponsorNew":"Hasten Biopharmaceutic \/ Hasten Biopharmaceutic","highestDevelopmentStatusID":"10","companyTruncated":"Hasten Biopharmaceutic \/ Hasten Biopharmaceutic"},{"orgOrder":0,"company":"Hasten Biopharmaceutic","sponsor":"Takeda Pharmaceutical","pharmaFlowCategory":"D","therapeuticArea":"Cardiology\/Vascular Diseases","country":"JAPAN","productType":"Other Small Molecule","year":"2020","type":"Divestment","leadProduct":"Urapidil Hydrochloride","moa":"||AR-alpha1","graph1":"Cardiology\/Vascular Diseases","graph2":"Approved FDF","graph3":"Hasten Biopharmaceutic","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Injection","sponsorNew":"Hasten Biopharmaceutic \/ Hasten Biopharmaceutic","highestDevelopmentStatusID":"15","companyTruncated":"Hasten Biopharmaceutic \/ Hasten Biopharmaceutic"},{"orgOrder":0,"company":"Hasten Biopharmaceutic","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Cardiology\/Vascular Diseases","country":"CHINA","productType":"Protein","year":"2024","type":"Inapplicable","leadProduct":"Inapplicable","moa":"||Subtilisin\/kexin type 9","graph1":"Cardiology\/Vascular Diseases","graph2":"Phase III","graph3":"Hasten Biopharmaceutic","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Hasten Biopharmaceutic \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Hasten Biopharmaceutic \/ Inapplicable"},{"orgOrder":0,"company":"Hasten Biopharmaceutic","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Cardiology\/Vascular Diseases","country":"CHINA","productType":"Undisclosed","year":"2024","type":"Inapplicable","leadProduct":"HST101","moa":"||PCSK9","graph1":"Cardiology\/Vascular Diseases","graph2":"Phase I","graph3":"Hasten Biopharmaceutic","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Hasten Biopharmaceutic \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Hasten Biopharmaceutic \/ Inapplicable"}]

Find Clinical Drug Pipeline Developments & Deals by Hasten Biopharmaceutic

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          August 23, 2024

                          Lead Product(s) : Lerodalcibep,Inapplicable

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Inapplicable

                          July 16, 2024

                          Lead Product(s) : HST101,Inapplicable

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : Through this acquisition, Hasten leverages commercial rights to treatments for various chronic disease, which include the approved product Edarbi (azilsartan medoxomil), indicated for hypertension.

                          Product Name : Edarbi

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          June 28, 2024

                          Lead Product(s) : Azilsartan,Inapplicable

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Approved FDF

                          Recipient : Celltrion

                          Deal Size : Undisclosed

                          Deal Type : Acquisition

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                          04

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : LIB003 (lerodalcibep) is a potential best in class, novel, small binding protein, third-generation PCSK9 inhibitor, which is being evaluated for the treatment and prevention of cardiovascular disease.

                          Product Name : Undisclosed

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          March 19, 2024

                          Lead Product(s) : Lerodalcibep,Inapplicable

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Phase III

                          Recipient : LIB Therapeutics

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : Through the acquisition, Hasten will own the Marketing Authorisation Holder rights of products in 8 countries, which includes Edarbi (azilsartan medoxomil) indicated for the treatment of hypertension.

                          Product Name : Edarbi

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          February 07, 2024

                          Lead Product(s) : Azilsartan,Inapplicable

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Approved FDF

                          Recipient : Celltrion

                          Deal Size : Undisclosed

                          Deal Type : Acquisition

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                          06

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : Under the terms of the agreement, LIB has granted Hasten the exclusive rights to develop and commercialize LIB003 (lerodalcibep), a next-generation, PCSK9 inhibitor, for patients at very high and high-risk of cardiovascular disease, in Greater China.

                          Product Name : Undisclosed

                          Product Type : Protein

                          Upfront Cash : $20.0 million

                          December 09, 2023

                          Lead Product(s) : Lerodalcibep,Inapplicable

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Phase III

                          Recipient : LIB Therapeutics

                          Deal Size : $325.0 million

                          Deal Type : Licensing Agreement

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                          07

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : The proceeds will fund the future acquisitions and business development of five cardiovascular and metabolic products, including Ebrantil®, Edarbi®, Blopress®, Basen®, and Actos®. Edarbi (azilsartan medoxomil) is an angiotensin II receptor blocker, ...

                          Product Name : Edarbi

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          April 20, 2023

                          Lead Product(s) : Azilsartan,Inapplicable

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Approved FDF

                          Sponsor : CBC Group

                          Deal Size : $315.0 million

                          Deal Type : Financing

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                          08

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : Under the agreement, Hasten acquired Roche's China mainland rights for Rocephin® (ceftriaxone sodium), a long-acting, broad spectrum cephalosporin antibiotic, including the product's marketing authorization and certain intellectual property, including t...

                          Product Name : Rocephin

                          Product Type : Antibiotic

                          Upfront Cash : Undisclosed

                          April 05, 2023

                          Lead Product(s) : Ceftriaxone,Inapplicable

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved FDF

                          Recipient : F. Hoffmann-La Roche

                          Deal Size : Undisclosed

                          Deal Type : Acquisition

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                          09

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : Under the acquisition agreement, Hasten Biopharma will have exclusive rights to five drugs including, Ebrantil (urapidil), Edarbi (azilsartan medoxomil), Blopress (candesartan cilexetil), Basen®, and Actos® in mainland China.

                          Product Name : Edarbi

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          March 31, 2022

                          Lead Product(s) : Azilsartan,Inapplicable

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Approved FDF

                          Recipient : Takeda Pharmaceutical

                          Deal Size : Undisclosed

                          Deal Type : Acquisition

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                          10

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : The portfolio to be divested to Hasten includes cardiovascular and metabolism products sold in mainland China which includes Ebrantil®.

                          Product Name : Ebrantil

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          December 21, 2020

                          Lead Product(s) : Urapidil Hydrochloride,Inapplicable

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Approved FDF

                          Recipient : Takeda Pharmaceutical

                          Deal Size : $322.0 million

                          Deal Type : Divestment

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