Company profile for GV20 Therapeutics

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About

GV20 Therapeutics, established in 2016 with locations in Cambridge, USA, and Shanghai, China, is at the forefront of cancer immunology research. Leveraging high-throughput functional genomics and artificial intelligence (AI) methodologies, the company identifies novel drug targets in cancer immunology and develops effective antibody drugs. Through its proprietary antibody drug discovery engine, GV20 has built a robust portfoli...
GV20 Therapeutics, established in 2016 with locations in Cambridge, USA, and Shanghai, China, is at the forefront of cancer immunology research. Leveraging high-throughput functional genomics and artificial intelligence (AI) methodologies, the company identifies novel drug targets in cancer immunology and develops effective antibody drugs. Through its proprietary antibody drug discovery engine, GV20 has built a robust portfolio of immuno-oncology antibody drug candidates for cancer treatment.

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CONTACT DETAILS

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Country
Country
U.S.A
Address
Address
Cambridge, MA 02139
Telephone
Telephone
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YouTube
Twitter
Twitter

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NEWS #PharmaBuzz

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https://www.prnewswire.com/news-releases/gv20-therapeutics-announces-achievement-of-milestone-under-antibody-drug-conjugate-collaboration-with-mitsubishi-tanabe-pharma-corporation-302625157.html

PR NEWSWIRE
25 Nov 2025

https://www.prnewswire.com/news-releases/gv20-therapeutics-to-present-updated-phase-1-monotherapy-data-on-gv20-0251-at-the-asco-annual-meeting-2025-302463357.html

PR NEWSWIRE
23 May 2025

https://www.prnewswire.com/news-releases/gv20-therapeutics-announces-collaboration-agreement-with-mitsubishi-tanabe-pharma-corporation-to-develop-novel-antibody-drug-conjugates-302411169.html

PR NEWSWIRE
27 Mar 2025

https://www.prnewswire.com/news-releases/gv20-therapeutics-presents-promising-phase-1-monotherapy-data-on-novel-checkpoint-inhibitor-gv20-0251-at-esmo-congress-2024-302247149.html

PR NEWSWIRE
16 Sep 2024

https://www.prnewswire.com/news-releases/gv20-therapeutics-to-present-clinical-data-on-gv20-0251-at-the-esmo-congress-2024-302225841.html

PR NEWSWIRE
21 Aug 2024

https://www.prnewswire.com/news-releases/gv20-therapeutics-announces-publication-in-cell-highlighting-the-discovery-of-igsf8-as-an-innate-immune-checkpoint-and-cancer-immunotherapy-target-302126064.html

PR NEWSWIRE
24 Apr 2024

Drugs in Development

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Details:

The collaboration aims to develop an undisclosed antibody-drug conjugate for cancer treatment.


Lead Product(s): Undisclosed,Inapplicable

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: Discovery PlatformProduct Type: Antibody-drug Conjugate

Sponsor: Mitsubishi Tanabe Pharma

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration November 25, 2025

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Global ChemShow
Not Confirmed
Global ChemShow
Not Confirmed

Details : The collaboration aims to develop an undisclosed antibody-drug conjugate for cancer treatment.

Product Name : Undisclosed

Product Type : Antibody-drug Conjugate

Upfront Cash : Undisclosed

November 25, 2025

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Details:

GV20-0251 is a Other Large Molecule drug candidate, which is currently being evaluated in Phase I clinical studies for the treatment of Carcinoma, Hepatocellular.


Lead Product(s): GV20-0251,Inapplicable

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: Phase IProduct Type: Miscellaneous

Recipient: West China Hospital

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable August 06, 2025

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Global ChemShow
Not Confirmed
Global ChemShow
Not Confirmed

Lead Product(s) : GV20-0251,Inapplicable

Therapeutic Area : Oncology

Highest Development Status : Phase I

Recipient : West China Hospital

Deal Size : Inapplicable

Deal Type : Inapplicable

Details : GV20-0251 is a Other Large Molecule drug candidate, which is currently being evaluated in Phase I clinical studies for the treatment of Carcinoma, Hepatocellular.

Product Name : Undisclosed

Product Type : Miscellaneous

Upfront Cash : Inapplicable

August 06, 2025

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Details:

GV20-0251 is a Other Large Molecule drug candidate, which is currently being evaluated in Phase I/ Phase II clinical studies for the treatment of Neoplasms.


Lead Product(s): GV20-0251,Inapplicable

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: Phase I/ Phase IIProduct Type: Miscellaneous

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable July 17, 2025

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Global ChemShow
Not Confirmed
Global ChemShow
Not Confirmed

Lead Product(s) : GV20-0251,Inapplicable

Therapeutic Area : Oncology

Highest Development Status : Phase I/ Phase II

Partner/Sponsor/Collaborator : Undisclosed

Deal Size : Inapplicable

Deal Type : Inapplicable

Details : GV20-0251 is a Other Large Molecule drug candidate, which is currently being evaluated in Phase I/ Phase II clinical studies for the treatment of Neoplasms.

Product Name : Undisclosed

Product Type : Miscellaneous

Upfront Cash : Inapplicable

July 17, 2025

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Details:

Under this collaboration, MTPC will leverage GV20's antibodies, which are specifically directed against novel tumor antigen targets discovered through STEAD AI platform, to generate ADCs.


Lead Product(s): Undisclosed

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: Discovery PlatformProduct Type: Antibody-drug Conjugate

Sponsor: Mitsubishi Tanabe Pharma

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration March 26, 2025

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04

Global ChemShow
Not Confirmed
Global ChemShow
Not Confirmed

Details : Under this collaboration, MTPC will leverage GV20's antibodies, which are specifically directed against novel tumor antigen targets discovered through STEAD AI platform, to generate ADCs.

Product Name : Undisclosed

Product Type : Antibody-drug Conjugate

Upfront Cash : Undisclosed

March 26, 2025

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Details:

Under the agreement, GV20 will evaluate its lead program GV20-0251, an antibody targeting immune checkpoint IGSF8, in combination with Merck's anti-PD-1, KEYTRUDA, for advanced tumors.


Lead Product(s): GV20-0251,Pembrolizumab

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: Phase IProduct Type: Miscellaneous

Sponsor: Merck & Co

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration April 18, 2024

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Global ChemShow
Not Confirmed
Global ChemShow
Not Confirmed

Details : Under the agreement, GV20 will evaluate its lead program GV20-0251, an antibody targeting immune checkpoint IGSF8, in combination with Merck's anti-PD-1, KEYTRUDA, for advanced tumors.

Product Name : Undisclosed

Product Type : Miscellaneous

Upfront Cash : Undisclosed

April 18, 2024

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Details:

GV20-025 is the first ever AI-designed antibody against an AI-predicated target, which is being evaluated for the treatment of patients with solid tumors.


Lead Product(s): GV20-0251,Inapplicable

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: Phase IProduct Type: Miscellaneous

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable April 08, 2024

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06

Global ChemShow
Not Confirmed
Global ChemShow
Not Confirmed

Lead Product(s) : GV20-0251,Inapplicable

Therapeutic Area : Oncology

Highest Development Status : Phase I

Partner/Sponsor/Collaborator : Undisclosed

Deal Size : Inapplicable

Deal Type : Inapplicable

Details : GV20-025 is the first ever AI-designed antibody against an AI-predicated target, which is being evaluated for the treatment of patients with solid tumors.

Product Name : Undisclosed

Product Type : Miscellaneous

Upfront Cash : Inapplicable

April 08, 2024

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Details:

GV20-0251 is a Other Large Molecule drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Neoplasms.


Lead Product(s): GV20-0251,Inapplicable

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: Phase I/ Phase IIProduct Type: Miscellaneous

Sponsor: Merck & Co

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable December 30, 2022

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07

Global ChemShow
Not Confirmed
Global ChemShow
Not Confirmed

Details : GV20-0251 is a Other Large Molecule drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Neoplasms.

Product Name : Undisclosed

Product Type : Miscellaneous

Upfront Cash : Inapplicable

December 30, 2022

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