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The collaboration aims to discover and develop chimeric antigen receptor (CAR) T-cell therapies, and armoring technologies, for up to three oncology targets, including in ovarian cancer and other solid tumors.


Lead Product(s): CAR T-Cell Therapy

Therapeutic Area: Oncology Product Name: Undisclosed

Highest Development Status: DiscoveryProduct Type: Cell and Gene therapy

Partner/Sponsor/Collaborator: Roswell Park Comprehensive Cancer Center

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration November 01, 2023

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The financing will be used to advance company's Generative AI pipeline of preclinical and clinical protein therapeutics, including GB-0669, a monoclonal antibody targeting a highly conserved region of the spike protein, in SARS-CoV-2.


Lead Product(s): GB-0669

Therapeutic Area: Infections and Infectious Diseases Product Name: GB-0669

Highest Development Status: Phase IProduct Type: Large molecule

Partner/Sponsor/Collaborator: Amgen Inc

Deal Size: $273.0 million Upfront Cash: Undisclosed

Deal Type: Series C Financing September 14, 2023

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The collaboration aims to jointly discover and co-develop protein therapeutics for up to 5 oncology targets in advanced cancers, including small-cell and NSCLC. The agreement combines Generate:Biomedicines’ The Generate Platform with MD Anderson’s clinical research expertise.


Lead Product(s): Undisclosed

Therapeutic Area: Oncology Product Name: Undisclosed

Highest Development Status: DiscoveryProduct Type: Undisclosed

Partner/Sponsor/Collaborator: The University of Texas MD Anderson Cancer Center

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration April 27, 2023

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Generate Biomedicine's integrated in silico design and wet lab capabilities combined with Amgen to harness its machine-learning-enabled technology to discover and develop protein therapeutics for five clinical targets across a range of therapeutic areas and modalities.


Lead Product(s): Engineered Protein-based Therapy

Therapeutic Area: Technology Product Name: Undisclosed

Highest Development Status: Discovery PlatformProduct Type: Large molecule

Partner/Sponsor/Collaborator: Amgen Inc

Deal Size: $1,900.0 million Upfront Cash: $50.0 million

Deal Type: Collaboration January 06, 2022

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