CODA Biotherapeutics’ revolutionary chemogenetic platform aims to control the activity of neurons to treat disease. With chemogenetics, target neuronal populations are modified using gene therapy to express a tunable ligand-gated ion channel. These ligand-gated ion channels are engineered to be highly responsive to a specific proprietary small molecule but are otherwise inactive. The interaction of the small molecule and eng...
CODA Biotherapeutics’ revolutionary chemogenetic platform aims to control the activity of neurons to treat disease. With chemogenetics, target neuronal populations are modified using gene therapy to express a tunable ligand-gated ion channel. These ligand-gated ion channels are engineered to be highly responsive to a specific proprietary small molecule but are otherwise inactive. The interaction of the small molecule and engineered receptor allow for exquisite, dose-dependent control of the neurons to generate therapeutic effect.
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