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Cadrenal Therapeutics
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Under the partnership, Sage Group will assist Cadrenal in exploring strategic partnerships, co-development and licensing agreements for ATI-5923 (tecarfarin), a late-stage, novel, oral and reversible anticoagulant designed to prevent heart attacks, strokes and deaths.


Lead Product(s): Tecarfarin,Warfarin Sodium

Therapeutic Area: Cardiology/Vascular Diseases Product Name: ATI-5923

Highest Development Status: Phase II/ Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: The Sage Group

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Partnership December 12, 2023

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Tecarfarin is an vitamin K antagonist (VKA), taken once a day as an oral anticoagulant like warfarin, which is investigated for the treatment of patients with antiphospholipid syndrome (APS) who require chronic anticoagulation.


Lead Product(s): Tecarfarin

Therapeutic Area: Immunology Product Name: Undisclosed

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable August 30, 2023

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Tecarfarin is an vitamin K antagonist (VKA), taken once a day as an oral anticoagulant like warfarin, which is investigated for the treatment of implanted medical devices for heart diseases.


Lead Product(s): Tecarfarin

Therapeutic Area: Cardiology/Vascular Diseases Product Name: Undisclosed

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable August 01, 2023

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The Company intends to use the net proceeds in developing tecarfarin, a novel cardiorenal therapy for the prevention of systemic thromboembolism of cardiac origin in patients with end-stage renal disease, or ESRD, and atrial fibrillation (irregular heartbeat), or AFib.


Lead Product(s): Tecarfarin

Therapeutic Area: Immunology Product Name: Undisclosed

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Boustead Securities

Deal Size: $7.0 million Upfront Cash: Undisclosed

Deal Type: Public Offering January 24, 2023

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Tecarfarin is a Vitamin K antagonist oral anticoagulant designed to target a different pathway than the most commonly prescribed drugs used in the treatment of thrombosis and AFib.


Lead Product(s): Tecarfarin

Therapeutic Area: Hematology Product Name: Undisclosed

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable January 23, 2023

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The net proceeds will be used for developing tecarfarin, a novel cardiorenal therapy with orphan drug designation for the prevention of systemic thromboembolism (blood clots) of cardiac origin in patients with end-stage renal disease, or ESRD, and atrial fibrillation.


Lead Product(s): Tecarfarin

Therapeutic Area: Immunology Product Name: Undisclosed

Highest Development Status: Phase IIIProduct Type: Small molecule

Partner/Sponsor/Collaborator: Boustead Securities

Deal Size: $7.0 million Upfront Cash: Undisclosed

Deal Type: Public Offering January 20, 2023

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